{
  "id": 6961,
  "label": "autism spectrum disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005258",
  "properties": {
    "xrefs": [
      "DOID:0060041",
      "EFO:0003756",
      "MEDGEN:307153",
      "NCIT:C88412",
      "Orphanet:106",
      "SCTID:408856003",
      "UMLS:C1510586",
      "icd11.foundation:437815624"
    ],
    "synonyms": [
      "autism spectrum disorder",
      "autistic spectrum disorder",
      "pervasive developmental disorder - not otherwise specified",
      "pervasive developmental disorders",
      "atypical autism"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A spectrum of developmental disorders that includes autism, and Asperger syndrome. Signs and symptoms include poor communication skills, defective social interactions, and repetitive behaviors."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 3009,
      "label": "pervasive developmental disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7159,
        23791
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060040",
          "GARD:0027041",
          "ICD9:299.80",
          "MEDGEN:99336",
          "MESH:D002659",
          "NCIT:C97179",
          "SCTID:35919005",
          "UMLS:C0524528"
        ],
        "synonyms": [
          "pervasive child development disorders",
          "pervasive development disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A category of developmental disorders characterized by impaired communication and socialization skills. The impairments are incongruent with the individual's developmental level or mental age. These disorders can be associated with general medical or genetic conditions."
      },
      "child_count": 10,
      "reference_id": "MONDO:0000594"
    }
  ],
  "children": [
    {
      "id": 6962,
      "label": "autism",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6961
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12849",
          "EFO:0003758",
          "HP:0000717",
          "ICD10CM:F84.0",
          "ICD9:299.0",
          "MEDGEN:13966",
          "MESH:D001321",
          "NCIT:C97161",
          "OMIM:209850",
          "UMLS:C0004352"
        ],
        "synonyms": [
          "autism spectrum disorder",
          "Kanner's syndrome",
          "autism",
          "autism (disease)",
          "infantile autism",
          "autism, susceptiblity to",
          "autistic disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Persistent deficits in social interaction and communication and interaction as well as a markedly restricted repertoire of activity and interest as well as repetitive patterns of behavior."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005260"
    },
    {
      "id": 24036,
      "label": "PAX5-related B lymphopenia and autism spectrum disorder",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4332,
        6961,
        24226
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026131"
        ],
        "synonyms": [
          "hypogammaglobulinemia and autism spectrum disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "PAX5 deficiency causing neurodevelopmental abnormalities including autism spectrum disorder in addition to hypogammaglobulinemia due to early B cell developmental block and impaired immune responses."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100299"
    },
    {
      "id": 24332,
      "label": "autism spectrum disorder 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6961
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050432",
          "GARD:0028001",
          "MESH:D020817",
          "NCIT:C97159",
          "Orphanet:1162",
          "SCTID:23560001",
          "icd11.foundation:366940030"
        ],
        "synonyms": [
          "Asperger syndrome",
          "autism spectrum disorder without disorder of intellectual development and with mild or no impairment of functional language"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "The mildest form of autism spectrum disorder, characterized by difficulties with social communication and restricted, repetitive behaviors, requiring minimal support for daily functioning."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100610"
    },
    {
      "id": 24333,
      "label": "autism spectrum disorder 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6961
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0028002"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A moderate form of autism spectrum disorder marked by more significant challenges in social communication and more noticeable restricted, repetitive behaviors, requiring substantial support for daily functioning."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100611"
    },
    {
      "id": 24334,
      "label": "autism spectrum disorder 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6961
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0028003"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "The most severe form of autism spectrum disorder, characterized by severe impairments in social communication and extreme restricted, repetitive behaviors, requiring very substantial support for daily functioning."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100612"
    }
  ],
  "roots": [
    {
      "id": 3009,
      "label": "pervasive developmental disorder"
    }
  ]
}