{
  "id": 6971,
  "label": "lung disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005275",
  "properties": {
    "xrefs": [
      "DOID:850",
      "EFO:0003818",
      "ICD9:518.89",
      "MEDGEN:7399",
      "MESH:D008171",
      "NCIT:C3198",
      "SCTID:19829001",
      "UMLS:C0024115"
    ],
    "synonyms": [
      "disease of lung",
      "disease or disorder of lung",
      "disorder of lung",
      "lung disease",
      "lung disease or disorder",
      "lung disorder",
      "lung disorders",
      "pulmonary disease",
      "pulmonary diseases",
      "pulmonary disorder",
      "pulmonary disorders"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A disease involving the lung."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 33,
  "parents": [
    {
      "id": 2809,
      "label": "lower respiratory tract disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6815
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050161",
          "EFO:0009433",
          "ICD9:478.1",
          "ICD9:478.19",
          "MEDGEN:712703",
          "SCTID:128272009",
          "UMLS:C1290325",
          "icd11.foundation:1582386590"
        ],
        "synonyms": [
          "disease of lower respiratory tract",
          "disease or disorder of lower respiratory tract",
          "disorder of lower respiratory tract",
          "lower respiratory tract disease",
          "lower respiratory tract disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A disease involving the lower respiratory tract."
      },
      "child_count": 5,
      "reference_id": "MONDO:0000270"
    }
  ],
  "children": [
    {
      "id": 2807,
      "label": "aspiration pneumonia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050152",
          "HP:0011951",
          "MEDGEN:10814",
          "MESH:D011015",
          "SCTID:422588002",
          "UMLS:C0032290"
        ],
        "synonyms": [
          "Mendelson syndrome",
          "Mendelson's syndrome",
          "Mendelsons syndrome",
          "Pneumonias, aspiration",
          "acid aspiration syndrome",
          "acid aspiration syndromes",
          "aspiration Pneumonias",
          "aspiration pneumonia",
          "aspiration pneumonia (disease)",
          "gastric acid aspiration syndrome",
          "syndrome, Mendelson",
          "syndrome, Mendelson's",
          "syndrome, acid aspiration",
          "syndromes, acid aspiration",
          "inhalation pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A type of lung inflammation resulting from the aspiration of food, liquid, or gastric contents into the upper respiratory tract."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000265"
    },
    {
      "id": 3117,
      "label": "lung abscess",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6939,
        6971,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060317",
          "EFO:1001362",
          "HP:0025044",
          "ICD9:513.0",
          "MEDGEN:7397",
          "MESH:D008169",
          "NCIT:C99090",
          "SCTID:73452002",
          "UMLS:C0024110"
        ],
        "synonyms": [
          "lung abscess",
          "lung abscess (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A bacterial, fungal or parasitic abscess that develops in the lung parenchyma. Causes include aspiration pneumonia, necrotizing pneumonia, necrotizing malignant tumors, and Wegener's granulomatosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000744"
    },
    {
      "id": 3283,
      "label": "pneumonic plague",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971,
        18984,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10398",
          "GARD:0022865",
          "ICD10CM:A20.2",
          "ICD9:020.3",
          "ICD9:020.4",
          "ICD9:020.5",
          "MEDGEN:105580",
          "SCTID:35339003",
          "UMLS:C0524688",
          "icd11.foundation:1983098110"
        ],
        "synonyms": [
          "primary pneumonic plague",
          "secondary pneumonic plague"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A plague in which the bacteria have infected the lungs."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001024"
    },
    {
      "id": 3655,
      "label": "pulmonary alveolar proteinosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12120",
          "ICD9:516.0",
          "MEDGEN:1763046",
          "MESH:D011649",
          "NANDO:1200746",
          "NCIT:C85037",
          "SCTID:10501004",
          "UMLS:C5400698",
          "icd11.foundation:1869739196"
        ],
        "synonyms": [
          "PAP",
          "pulmonary alveolar proteinosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare lung disorder characterized by the filling of the pulmonary alveoli with proteinaceous material which stains positive with periodic acid-Schiff stain. It may be idiopathic or secondary due to hematologic malignancies or the inhalation of mineral dusts. Signs and symptoms include dyspnea, cough and low grade fever."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001437"
    },
    {
      "id": 4194,
      "label": "pulmonary systemic sclerosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6827,
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1578",
          "GARD:0023060",
          "ICD9:517.2",
          "MEDGEN:573414",
          "SCTID:196133001",
          "UMLS:C0339904"
        ],
        "synonyms": [
          "lung involvement in systemic sclerosis",
          "scleroderma lung disease",
          "scleroderma of lung"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0002047"
    },
    {
      "id": 4382,
      "label": "obstructive lung disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2320",
          "MEDGEN:1387",
          "MESH:D008173",
          "UMLS:C0001883"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Any disorder marked by obstruction of conducting airways of the lung. airway obstruction may be acute, chronic, intermittent, or persistent."
      },
      "child_count": 1,
      "reference_id": "MONDO:0002267"
    },
    {
      "id": 4545,
      "label": "bronchiolitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2942",
          "HP:0011950",
          "ICD9:466.19",
          "MEDGEN:14235",
          "MESH:D001988",
          "NCIT:C39658",
          "SCTID:4120002",
          "UMLS:C0006271"
        ],
        "synonyms": [
          "bronchiolitis",
          "bronchiolitis (disease)",
          "wheezy bronchitis",
          "RSV bronchiolitis",
          "viral bronchiolitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Inflammation of the bronchioles characterized by swelling of the bronchioles and mucus accumulation. It is usually caused by the respiratory syncytial virus and affects children. Signs and symptoms include coughing, wheezing, and shortness of breath."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002465"
    },
    {
      "id": 4935,
      "label": "pulmonary immaturity",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:424",
          "ICD10CM:P28.0",
          "ICD9:770.4",
          "MEDGEN:542574",
          "SCTID:42908004",
          "UMLS:C0270163"
        ],
        "synonyms": [
          "primary atelectasis of newborn"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0002929"
    },
    {
      "id": 6382,
      "label": "rheumatoid arthritis-associated interstitial lung disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971,
        9682
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:849",
          "ICD9:714.81",
          "MEDGEN:681135",
          "SCTID:398726004",
          "UMLS:C0994344"
        ],
        "synonyms": [
          "RA-ILD",
          "rheumatoid lung disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A group of lung problems related to rheumatoid arthritis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004586"
    },
    {
      "id": 6389,
      "label": "pulmonary embolism and infarction",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8516",
          "ICD9:415.1",
          "ICD9:415.19",
          "MEDGEN:19577",
          "MESH:D054060",
          "NCIT:C50714",
          "SCTID:64662007",
          "UMLS:C0034074"
        ],
        "synonyms": [
          "infarction, pulmonary",
          "lung infarction",
          "pulmonary infarction"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Localized necrosis of lung tissue caused by obstruction of the arterial blood supply, most often due to pulmonary embolism."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004597"
    },
    {
      "id": 7271,
      "label": "acute chest syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        6971,
        20092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1584",
          "EFO:0007129",
          "ICD9:517.3",
          "MEDGEN:196643",
          "MESH:D056586",
          "NCIT:C138179",
          "SCTID:372146004",
          "UMLS:C0742343"
        ],
        "synonyms": [
          "ACS"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A vaso-occlusive crisis of the pulmonary vasculature occurring in patients with sickle cell disease. It is characterized by the presence of a new radiodensity on a chest radiograph accompanied by fever, cough, sputum production, dyspnea, or hypoxia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005632"
    },
    {
      "id": 7386,
      "label": "fungal lung infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4188,
        6971,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007278",
          "MEDGEN:6144",
          "MESH:D008172",
          "UMLS:C0024116"
        ],
        "synonyms": [
          "Fungi caused lung disease",
          "Fungi lung disease",
          "fungal disease, pulmonary",
          "fungal diseases, pulmonary",
          "fungal infection, pulmonary",
          "fungal infections, pulmonary",
          "fungal lung disease",
          "fungal lung diseases",
          "lung disease, fungal",
          "pulmonary fungal disease",
          "pulmonary fungal diseases",
          "pulmonary fungal infection",
          "pulmonary fungal infections"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Pulmonary diseases caused by fungal infections, usually through hematogenous spread."
      },
      "child_count": 15,
      "reference_id": "MONDO:0005766"
    },
    {
      "id": 7459,
      "label": "middle lobe syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2810",
          "EFO:0007367",
          "MEDGEN:6393",
          "MESH:D008878",
          "SCTID:28295001",
          "UMLS:C0026069"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Atelectasis of the right middle pulmonary lobe, with chronic pneumonitis. (Dorland, 27th ed)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0005847"
    },
    {
      "id": 8363,
      "label": "pulmonary coin lesion",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5364",
          "MEDGEN:3522",
          "MESH:D003074",
          "UMLS:C0009250"
        ],
        "synonyms": [
          "coin lesion of lung (context-dependent category)",
          "coin lesion of lung (finding)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A single lung lesion that is characterized by a small round mass of tissue, usually less than 1 cm in diameter, and can be detected by chest radiography. A solitary pulmonary nodule can be associated with neoplasm, tuberculosis, cyst, or other anomalies in the lung, the chest wall, or the pleura."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006931"
    },
    {
      "id": 8365,
      "label": "pulmonary plasma cell granuloma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3677",
          "ICD9:518.89",
          "MEDGEN:38832",
          "MESH:D016726",
          "SCTID:1648002",
          "UMLS:C0085269",
          "icd11.foundation:215620908"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A tumor-like inflammatory lesion of the lung that is composed of plasma cells and fibrous tissue. It is also known as an inflammatory pseudotumor, often with calcification and measuring between 2 and 5 cm in diameter."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006933"
    },
    {
      "id": 8397,
      "label": "silo filler disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4374",
          "MEDGEN:11428",
          "MESH:D012832",
          "SCTID:61233003",
          "UMLS:C0037120",
          "icd11.foundation:1960063586"
        ],
        "synonyms": [
          "silo filler disease",
          "silo filler's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A form of alveolitis or pneumonitis caused by hypersensitivity to high level of inhaled nitrogen oxides, decomposition products of silage."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006972"
    },
    {
      "id": 11131,
      "label": "pulmonary alveolar microlithiasis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5714,
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12117",
          "GARD:0011894",
          "ICD10CM:J84.02",
          "ICD9:516.2",
          "MEDGEN:56374",
          "MESH:C562405",
          "MedDRA:10037315",
          "NANDO:2200202",
          "OMIM:265100",
          "Orphanet:60025",
          "SCTID:87153008",
          "UMLS:C0155912",
          "icd11.foundation:1220010076"
        ],
        "synonyms": [
          "pulmonary alveolar microlithiasis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Pulmonary alveolar microlithiasis is a disorder in which tiny fragments (microliths) of calcium phosphate gradually accumulate in the small air sacs (alveoli) of the lungs. These deposits eventually cause widespread damage to the alveoli and surrounding lung tissue (interstitial lung disease). People with this disorder may also develop a persistent cough and difficulty breathing (dyspnea), especially during physical exertion. Chest pain that worsens when coughing, sneezing, or taking deep breaths is another common feature. People with pulmonary alveolar microlithiasismay also develop calcium phosphate deposits in other organs and tissue of the body. Though the course of the disease can be variable,many casesslowly progress to lung fibrosis, respiratory failure, or cor pulmonale. The only effective therapy is lung transplantation. In some cases, pulmonary alveolar microlithiasis is caused by mutations in the SLC34A2 gene and inherited in an autosomal recessive manner."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009928"
    },
    {
      "id": 11139,
      "label": "pulmonary venoocclusive disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6971,
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5453",
          "GARD:0010153",
          "ICD9:416.8",
          "MEDGEN:18769",
          "MESH:D011668",
          "MedDRA:10037458",
          "NANDO:1200427",
          "NCIT:C85039",
          "OMIMPS:265450",
          "Orphanet:31837",
          "SCTID:89420002",
          "UMLS:C0034091",
          "icd11.foundation:1368993024"
        ],
        "synonyms": [
          "PVOD",
          "pulmonary capillary hemangiomatosis",
          "pulmonary veno-occlusive disease",
          "obstructive disease of the pulmonary veins"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A disorder characterized by pulmonary venous constriction or occlusion, resulting in pulmonary hypertension."
      },
      "child_count": 6,
      "reference_id": "MONDO:0009937"
    },
    {
      "id": 16549,
      "label": "acute lung injury",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971,
        20092,
        20408
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0004610",
          "MESH:D055371",
          "MedDRA:10069351",
          "NCIT:C155766",
          "Orphanet:178320",
          "SCTID:315345002"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A condition of lung damage that is characterized by bilateral pulmonary infiltrates (pulmonary edema) rich in neutrophils, and in the absence of clinical heart failure. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015796"
    },
    {
      "id": 16615,
      "label": "interstitial lung disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3082",
          "EFO:0004244",
          "ICD10CM:J80-J84",
          "MEDGEN:1788738",
          "MESH:D017563",
          "MedDRA:10022611",
          "NCIT:C164315",
          "Orphanet:182095",
          "SCTID:233703007",
          "UMLS:C5441745"
        ],
        "synonyms": [
          "ILD",
          "interstitial lung disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features."
      },
      "child_count": 14,
      "reference_id": "MONDO:0015925"
    },
    {
      "id": 18093,
      "label": "hantavirus pulmonary syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        6971,
        7400,
        18247,
        21376,
        23869
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14472",
          "EFO:0007296",
          "GARD:0000069",
          "ICD9:480.8",
          "MEDGEN:66205",
          "MESH:D018804",
          "MedDRA:10019143",
          "NCIT:C84747",
          "NORD:1216",
          "Orphanet:319247",
          "SCTID:120639003",
          "UMLS:C0243025",
          "icd11.foundation:582624609"
        ],
        "synonyms": [
          "HARDS",
          "Hantavirus",
          "Hantavirus-associated respiratory distress syndrome",
          "four corners hantavirus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An infection caused by Hantaviruses. It manifests with flu-like symptoms but it rapidly progresses to life-threatening respiratory problems."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017879"
    },
    {
      "id": 18509,
      "label": "pulmonary non-tuberculous mycobacterial infection",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971,
        20027,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012829",
          "MEDGEN:758704",
          "NORD:1887",
          "Orphanet:411703",
          "UMLS:C3472679",
          "icd11.foundation:1798822437"
        ],
        "synonyms": [
          "Nontuberculous Mycobacterial Lung Disease",
          "non-tuberculous mycobacterial lung disease",
          "nontuberculous mycobacterial lung disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018469"
    },
    {
      "id": 20352,
      "label": "respiratory failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11162",
          "EFO:0009686",
          "ICD9:518.83",
          "MEDGEN:257837",
          "MESH:D012131",
          "NCIT:C26872",
          "SCTID:39871006",
          "UMLS:C1145670",
          "icd11.foundation:370028006"
        ],
        "synonyms": [
          "failure, respiratory",
          "respiratory failure",
          "acute respiratory failure",
          "chronic respiratory failure",
          "acute and chronic respiratory failure",
          "acute-on-chronic respiratory failure"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021113"
    },
    {
      "id": 20356,
      "label": "lung neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971,
        20056,
        20518
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:7400",
          "MESH:D008175",
          "NCIT:C3200",
          "ONCOTREE:LUNG",
          "UMLS:C0024121"
        ],
        "synonyms": [
          "lung neoplasm",
          "lung neoplasm (disease)",
          "lung neoplasms",
          "lung tumor",
          "lung tumour",
          "neoplasm of lung",
          "neoplasm of the lung",
          "tumor of lung",
          "tumor of the lung",
          "tumour of lung",
          "tumour of the lung",
          "lung",
          "neoplasm, lung",
          "neoplasm, pulmonary",
          "neoplasms, lung",
          "neoplasms, pulmonary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm involving the lungs. Representative examples of benign neoplasms include adenoma, papilloma, chondroma, and endobronchial lipoma. Representative examples of malignant neoplasms include carcinoma, carcinoid tumor, sarcoma, and lymphoma."
      },
      "child_count": 30,
      "reference_id": "MONDO:0021117"
    },
    {
      "id": 20956,
      "label": "occupational lung disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971,
        24094
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:508.9",
          "MEDGEN:538557",
          "SCTID:86157004",
          "UMLS:C0264421"
        ],
        "synonyms": [
          "Occupational inhalation disease",
          "Occupational lung disease",
          "Occupational lung disorder",
          "Occupational pulmonary disease",
          "Occupational respiratory disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 16,
      "reference_id": "MONDO:0022736"
    },
    {
      "id": 21094,
      "label": "Wilson-Mikity syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010495",
          "ICD10CM:P27.0",
          "MEDGEN:78714",
          "SCTID:51577008",
          "UMLS:C0270171",
          "icd11.foundation:846899990"
        ],
        "synonyms": [
          "Wilson-Mikity syndrome",
          "wilson-mikity syndrome",
          "Pulmonary dysmaturity",
          "Pulmonary dysmaturity syndrome",
          "pulmonary dysmaturity"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0023011"
    },
    {
      "id": 21304,
      "label": "neonatal aspiration syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:578767",
          "NCIT:C118312",
          "SCTID:276533002",
          "UMLS:C0349468"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Aspiration of meconium, blood, amniotic fluid or gastric contents around the time of delivery resulting in clinical symptoms from airway obstruction, parenchymal injury, and ventilation-perfusion mismatch. This may lead to persistent pulmonary hypertension in the newborn."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024263"
    },
    {
      "id": 23261,
      "label": "pneumonitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001991",
          "MEDGEN:811420",
          "NCIT:C113159",
          "SCTID:205237003",
          "UMLS:C3714636",
          "icd11.foundation:1324545867"
        ],
        "synonyms": [
          "inflammation of lung parenchyma",
          "lung parenchyma inflammation",
          "pneumonitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An inflammatory process affecting the lung parenchyma. It is a milder form of lung inflammation compared to pneumonia."
      },
      "child_count": 12,
      "reference_id": "MONDO:0043905"
    },
    {
      "id": 24394,
      "label": "vanishing lung syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "VLS",
          "idiopathic giant bullous emphysema"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare form of irreversible damage to the pulmonary parenchyma often due to chronic obstructive pulmonary disease (COPD). It is associated with a spectrum of clinical manifestations, including worsening dyspnea, cough, declining pulmonary function, and occasionally spontaneous pneumothorax due to ruptured bullae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0600026"
    },
    {
      "id": 24396,
      "label": "restrictive pulmonary disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:43209",
          "NCIT:C91762",
          "SCTID:36485005",
          "UMLS:C0085581"
        ],
        "synonyms": [
          "Restrictive lung disease (disorder)",
          "restrictive lung disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Decreased lung volume and inadequate ventilation due to parenchymal lung disorders (e.g., interstitial pulmonary fibrosis) or extrapulmonary disorders (e.g., scoliosis). Patients present with shortness of breath and cough."
      },
      "child_count": 0,
      "reference_id": "MONDO:0600029"
    },
    {
      "id": 24399,
      "label": "shrinking lung syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:743060",
          "UMLS:C1960277"
        ],
        "synonyms": [
          "shrinking of the lung",
          "SLS",
          "small lungs"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare pulmonary complication of an underlying autoimmune disorder that is reported in association with systemic lupus erythematosus (SLE). Reduced lung volumes result in restrictive ventilatory defect and a preserved carbon monoxide transfer coefficient."
      },
      "child_count": 0,
      "reference_id": "MONDO:0700001"
    },
    {
      "id": 24832,
      "label": "dystrophic pulmonary ossification",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A rare lung disorder characterized by ectopic bone formation within lung parenchyma. DPO can be idiopathic or associated with a variety of cardiovascular, respiratory diseases or other disorders. There are mainly two forms of DPO: nodular and dendriform."
      },
      "child_count": 0,
      "reference_id": "MONDO:0800126"
    },
    {
      "id": 25245,
      "label": "pulmonary artery disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2933,
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:60001"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0851102"
    }
  ],
  "roots": [
    {
      "id": 2809,
      "label": "lower respiratory tract disorder"
    }
  ]
}