{
  "id": 6993,
  "label": "brain ischemia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005299",
  "properties": {
    "xrefs": [
      "DOID:2316",
      "ICD9:348.89",
      "MEDGEN:182975",
      "MESH:D002545",
      "NCIT:C78394",
      "SCTID:389100007",
      "UMLS:C0917798"
    ],
    "synonyms": [
      "brain ischaemic disease",
      "brain ischemia",
      "brain ischemic disease",
      "cerebrovascular ischemia",
      "ischaemic disease of brain",
      "ischemia cerebrovascular",
      "ischemic disease of brain"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Diminished or absent blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurologic damage."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 6784,
      "label": "ischemic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:326",
          "MEDGEN:5899",
          "MESH:D007511",
          "NCIT:C34738",
          "SCTID:52674009",
          "UMLS:C0022116"
        ],
        "synonyms": [
          "ischemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Lack of blood supply to an area of the body, resulting in impairment of tissue oxygenation."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005053"
    },
    {
      "id": 12183,
      "label": "cerebrovascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7209,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6713",
          "EFO:0003763",
          "ICD10CM:I60-I69",
          "ICD9:430-438",
          "ICD9:434.91",
          "ICD9:437.8",
          "ICD9:437.9",
          "MEDGEN:858",
          "MESH:D002561",
          "NCIT:C2938",
          "SCTID:62914000",
          "UMLS:C0007820",
          "icd11.foundation:843843448"
        ],
        "synonyms": [
          "cerebrovascular disease",
          "cerebrovascular disorder",
          "CVA",
          "CVA (cerebral vascular accident)",
          "cerebral infarction",
          "cerebrovascular accident",
          "stroke"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction."
      },
      "child_count": 48,
      "reference_id": "MONDO:0011057"
    }
  ],
  "children": [
    {
      "id": 6964,
      "label": "transient ischemic attack",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6993,
        29356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:224",
          "EFO:0003764",
          "HP:0002326",
          "ICD9:435",
          "ICD9:435.8",
          "ICD9:435.9",
          "MEDGEN:853",
          "MESH:D002546",
          "NCIT:C50781",
          "SCTID:266257000",
          "UMLS:C0007787",
          "icd11.foundation:826335789"
        ],
        "synonyms": [
          "TIA",
          "TIA - transient ischemic attack",
          "attack, transient ischaemic",
          "attack, transient ischemic",
          "ischaemic attack, transient",
          "ischemic attack, transient",
          "transient cerebral ischemia (disorder) [ambiguous]",
          "transient ischaemic attack (disease)",
          "transient ischaemic attacks",
          "transient ischemic attack",
          "transient ischemic attack (disease)",
          "transient ischemic attacks",
          "transient cerebral ischemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A brief attack (from a few minutes to an hour) of cerebral dysfunction of vascular origin, with no persistent neurological deficit."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005264"
    },
    {
      "id": 8152,
      "label": "brain hypoxia - ischemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6993
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:199862",
          "MESH:D020925",
          "UMLS:C0752308"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ischemia) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ischemic attack, transient; brain infarction; brain edema; coma; and other conditions."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006685"
    },
    {
      "id": 18588,
      "label": "pediatric arterial ischemic stroke",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2933,
        6993,
        29356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021824",
          "MEDGEN:1803840",
          "Orphanet:439175",
          "SCTID:1197363004",
          "UMLS:C5680049"
        ],
        "synonyms": [
          "childhood AIS",
          "childhood arterial ischaemic stroke",
          "childhood arterial ischemic stroke",
          "paediatric AIS",
          "pediatric AIS"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare ischemic disease characterized by focal cerebral ischemia and infarction due to blockage of a brain artery with subsequent impairment of blood supply and oxygenation of brain tissue."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018585"
    }
  ],
  "roots": [
    {
      "id": 6784,
      "label": "ischemic disease"
    },
    {
      "id": 12183,
      "label": "cerebrovascular disorder"
    }
  ]
}