{
  "id": 6994,
  "label": "chronic kidney disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005300",
  "properties": {
    "xrefs": [
      "DOID:784",
      "EFO:0003884",
      "ICD10CM:N18",
      "ICD10CM:N18.9",
      "ICD10WHO:N18",
      "ICD9:585",
      "MEDGEN:473458",
      "MESH:D007676",
      "NANDO:2100008",
      "NANDO:2100023",
      "NCIT:C80078",
      "SCTID:709044004",
      "UMLS:C1561643",
      "icd11.foundation:412389819"
    ],
    "synonyms": [
      "CKD - chronic kidney disease",
      "chronic kidney disease",
      "chronic renal disease",
      "kidney disease, chronic",
      "chronic renal failure syndrome",
      "chronic renal insufficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "Impairment of the renal function secondary to chronic kidney damage persisting for three or more months."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 6948,
      "label": "kidney disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4253
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:557",
          "EFO:0003086",
          "ICD9:583.81",
          "MEDGEN:9635",
          "MESH:D007674",
          "NCIT:C3149",
          "SCTID:90708001",
          "UMLS:C0022658"
        ],
        "synonyms": [
          "disease of kidney",
          "disease or disorder of kidney",
          "disorder of kidney",
          "kidney disease",
          "kidney disease or disorder",
          "kidney disorder",
          "renal disease",
          "renal disorder",
          "nephropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disease involving the kidney."
      },
      "child_count": 57,
      "reference_id": "MONDO:0005240"
    }
  ],
  "children": [
    {
      "id": 3359,
      "label": "chronic pyelonephritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6994,
        8370
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1076",
          "ICD9:590.0",
          "MEDGEN:39090",
          "NANDO:2100012",
          "NANDO:2200137",
          "NCIT:C123216",
          "SCTID:63302006",
          "UMLS:C0085697",
          "icd11.foundation:1346439976"
        ],
        "synonyms": [
          "pyelonephritis, chronic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Persistent pyelonephritis."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001110"
    },
    {
      "id": 3428,
      "label": "chronic rapidly progressive glomerulonephritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6994,
        17574
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11036",
          "GARD:0022895",
          "ICD9:582.4",
          "MEDGEN:574584",
          "SCTID:197614002",
          "UMLS:C0341694"
        ],
        "synonyms": [
          "chronic glomerulonephritis with lesion of rapidly progressive glomerulonephritis",
          "rapidly progressive glomerulonephritis, chronic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Chronic form of rapidly progressive glomerulonephritis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001184"
    },
    {
      "id": 6188,
      "label": "end stage renal failure",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6994
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:783",
          "ICD10CM:N18.5",
          "ICD10CM:N18.6",
          "ICD9:585.6",
          "MEDGEN:384526",
          "NCIT:C9439",
          "SCTID:46177005",
          "UMLS:C2316810"
        ],
        "synonyms": [
          "ESRD",
          "ESRD, end stage renal disease",
          "chronic kidney disease, stage 5",
          "disease (ESRD), end stage renal",
          "end stage kidney disease",
          "end stage kidney failure",
          "end stage renal disease",
          "end stage renal disease (ESRD)",
          "renal disease (ESRD), end stage",
          "renal disease, end stage"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Long-standing and persistent renal disease with glomerular filtration rate (GFR) less than 15 ml/min."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004375"
    },
    {
      "id": 6753,
      "label": "diabetic kidney disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6795,
        6994
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000401",
          "ICD9:250.4",
          "ICD9:250.40",
          "ICD9:583.81",
          "MEDGEN:8352",
          "MESH:D003928",
          "NCIT:C84417",
          "SCTID:127013003",
          "UMLS:C0011881",
          "icd11.foundation:615062102"
        ],
        "synonyms": [
          "DKD",
          "diabetic nephropathy",
          "type 1 diabetes nephropathy",
          "type 2 diabetes nephropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Progressive kidney disorder caused by vascular damage to the glomerular capillaries, in patients with diabetes mellitus. It is usually manifested with nephritic syndrome and glomerulosclerosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005016"
    },
    {
      "id": 21358,
      "label": "chronic renal failure syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3356,
        6994
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:585.9",
          "MEDGEN:9637",
          "MESH:D051436",
          "NANDO:2100023",
          "NCIT:C9438",
          "SCTID:90688005",
          "UMLS:C0022661"
        ],
        "synonyms": [
          "CRF - chronic renal failure",
          "Chronic renal disease",
          "chronic kidney failure",
          "chronic renal failure",
          "chronic renal failure disease",
          "kidney failure, chronic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Impairment of the renal function due to chronic kidney damage."
      },
      "child_count": 0,
      "reference_id": "MONDO:0024327"
    },
    {
      "id": 26365,
      "label": "arterionephrosclerosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6994
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0051066"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A chronic kidney disease that is characterized by arteriosclerosis, global glomerulosclerosis, and cortical fibrosis with tubular atrophy and loss."
      },
      "child_count": 0,
      "reference_id": "MONDO:0980737"
    }
  ],
  "roots": [
    {
      "id": 6948,
      "label": "kidney disorder"
    }
  ]
}