{
  "id": 6999,
  "label": "ankylosing spondylitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005306",
  "properties": {
    "xrefs": [
      "DOID:7147",
      "EFO:0003898",
      "ICD10CM:M45",
      "ICD10WHO:M45",
      "ICD9:720.0",
      "MEDGEN:11561",
      "MESH:D013167",
      "NANDO:1200870",
      "NCIT:C84564",
      "Orphanet:825",
      "SCTID:9631008",
      "UMLS:C0038013"
    ],
    "synonyms": [
      "ankylosing spondylarthritis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 5796,
      "label": "spondylitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20399,
        23502
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6590",
          "ICD9:720.8",
          "ICD9:720.89",
          "MEDGEN:11560",
          "MESH:D013166",
          "NCIT:C116779",
          "SCTID:84172003",
          "UMLS:C0038012"
        ],
        "synonyms": [
          "inflammation of vertebra",
          "vertebra inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "The inflammation of a vertebra."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003937"
    },
    {
      "id": 6822,
      "label": "spondyloarthropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6778,
        8264
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1123",
          "EFO:0000706",
          "MEDGEN:181888",
          "NCIT:C116778",
          "UMLS:C0949691"
        ],
        "synonyms": [
          "seronegative spondyloarthropathy",
          "spondyloarthritis",
          "spondylarthropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A group of inflammatory rheumatic diseases associated with arthritis and enthesitis, and often involving the axial skeleton. The most common form of spondyloarthritis is ankylosing spondylitis. Other forms include axial spondyloarthritis, peripheral spondyloarthritis, reactive arthritis, psoriatic arthritis/spondylitis and enteropathic arthritis/spondylitis."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005095"
    },
    {
      "id": 9682,
      "label": "rheumatoid arthritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3005,
        7203,
        7223
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7148",
          "EFO:0000685",
          "HP:0001370",
          "ICD9:714.0",
          "MEDGEN:2078",
          "MESH:D001172",
          "NCIT:C2884",
          "OMIM:180300",
          "Orphanet:284130",
          "SCTID:69896004",
          "UMLS:C0003873",
          "icd11.foundation:576319925"
        ],
        "synonyms": [
          "RA",
          "rheumatoid arthritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor."
      },
      "child_count": 21,
      "reference_id": "MONDO:0008383"
    },
    {
      "id": 22983,
      "label": "vertebral joint disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3140,
        8264
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0009477",
          "MEDGEN:1853166",
          "SCTID:372109003",
          "UMLS:C0541407"
        ],
        "synonyms": [
          "disease of intervertebral joint",
          "disease or disorder of intervertebral joint",
          "disorder of intervertebral joint",
          "disorder of joint of spine",
          "intervertebral joint disease",
          "intervertebral joint disease or disorder",
          "spondyloarthropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A disease that involves the intervertebral joint."
      },
      "child_count": 4,
      "reference_id": "MONDO:0037847"
    }
  ],
  "children": [
    {
      "id": 20069,
      "label": "juvenile ankylosing spondylitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6999
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0040092",
          "ICD10CM:M08.1",
          "MEDGEN:592563",
          "SCTID:239805001",
          "UMLS:C0409675"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020655"
    },
    {
      "id": 23207,
      "label": "juvenile spondyloarthropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6999
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:592564",
          "NCIT:C114347",
          "SCTID:239806000",
          "UMLS:C0409676"
        ],
        "synonyms": [
          "JSpA",
          "juvenile Spondyloarthritis",
          "juvenile spondyloarthropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A group of chronic, inflammatory childhood diseases characterized by arthritis and enthesitis. This disorder can affect the axial skeleton in late childhood or young adulthood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0043377"
    }
  ],
  "roots": [
    {
      "id": 5796,
      "label": "spondylitis"
    },
    {
      "id": 6822,
      "label": "spondyloarthropathy"
    },
    {
      "id": 9682,
      "label": "rheumatoid arthritis"
    },
    {
      "id": 22983,
      "label": "vertebral joint disorder"
    }
  ]
}