{
  "id": 7005,
  "label": "necrotizing enterocolitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005313",
  "properties": {
    "xrefs": [
      "EFO:0003928",
      "GARD:0009767",
      "ICD10CM:K55.3",
      "ICD9:777.5",
      "MEDGEN:105440",
      "MESH:D020345",
      "NCIT:C84915",
      "Orphanet:391673",
      "SCTID:2707005",
      "UMLS:C0520459",
      "icd11.foundation:141267925"
    ],
    "synonyms": [
      "NEC",
      "necrotizing enterocolitis",
      "necrotizing enterocolitis in fetus or newborn",
      "necrotizing enterocolitis in foetus or newborn"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "Necrotizing enterocolitis (NEC) is a devastating disease that affects mostly the intestine of premature infants. The wall of the intestine is invaded by bacteria, which cause local infection and inflammation that can ultimately destroy the wall of the bowel (intestine). Such bowel wall destruction can lead to perforation of the intestine and spillage of stool into the infant's abdomen, which can result in an overwhelming infection and death."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6756,
      "label": "intestinal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6151
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5295",
          "EFO:0009431",
          "ICD9:520-579",
          "ICD9:560-569",
          "ICD9:564",
          "ICD9:564.4",
          "ICD9:569",
          "ICD9:569.4",
          "ICD9:569.49",
          "ICD9:569.89",
          "ICD9:569.9",
          "ICD9:570-579",
          "ICD9:575",
          "MEDGEN:7130",
          "MESH:D007410",
          "NCIT:C26801",
          "SCTID:85919009",
          "UMLS:C0021831"
        ],
        "synonyms": [
          "disease of intestine",
          "disease or disorder of intestine",
          "disorder of intestine",
          "intestinal disease",
          "intestinal disorder",
          "intestine disease",
          "intestine disease or disorder",
          "disease, intestinal",
          "diseases, intestinal"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the small or large intestine."
      },
      "child_count": 58,
      "reference_id": "MONDO:0005020"
    },
    {
      "id": 10415,
      "label": "enterocolitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001481",
          "HP:0004387",
          "ICD9:558.9",
          "MEDGEN:4966",
          "MESH:D004760",
          "NCIT:C79573",
          "OMIM:226150",
          "SCTID:43752006",
          "UMLS:C0014356"
        ],
        "synonyms": [
          "enterocolitis",
          "enterocolitis (disease)"
        ],
        "definition": "An inflammatory process affecting the small intestine and colon. Causes include viruses, bacteria, radiation, and antibiotics use."
      },
      "child_count": 2,
      "reference_id": "MONDO:0009172"
    }
  ],
  "children": [
    {
      "id": 6425,
      "label": "perinatal necrotizing enterocolitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8677",
          "GARD:0024078",
          "MEDGEN:906305",
          "SCTID:397729009",
          "UMLS:C4082937"
        ],
        "synonyms": [
          "enterocolitis necrotizing",
          "necrotizing enterocolitis",
          "necrotizing enterocolitis in foetus or newborn",
          "enterocolitis, necrotizing"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A fulminating disease of neonates in which there is extensive mucosal ulceration, pseudomembrane formation, submucosal hemorrhage, and necrosis usually of the right colon, cecum, terminal ileum, and appendix, possibly due to perinatal intestinal ischemia and bacterial invasion. Progression can lead to necrosis, perforation and/or scarring of the intestinal tract."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004639"
    }
  ],
  "roots": [
    {
      "id": 6756,
      "label": "intestinal disorder"
    },
    {
      "id": 10415,
      "label": "enterocolitis"
    }
  ]
}