{
  "id": 7024,
  "label": "open-angle glaucoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005338",
  "properties": {
    "xrefs": [
      "DOID:1067",
      "EFO:0004190",
      "ICD10CM:H40.1",
      "ICD9:365.1",
      "ICD9:365.10",
      "ICD9:365.13",
      "MEDGEN:6611",
      "MESH:D005902",
      "NCIT:C34641",
      "SCTID:46168003",
      "SCTID:84494001",
      "UMLS:C0017612"
    ],
    "synonyms": [
      "POAG",
      "glaucoma, primary open angle",
      "open angle glaucoma",
      "pigmentary glaucoma",
      "primary open angle glaucoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "Chronic outflow obstruction of the eye's drainage canals that can lead to increased internal eye pressure and optic nerve damage."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 6774,
      "label": "glaucoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7019
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1686",
          "HP:0000501",
          "ICD10CM:H40",
          "ICD10CM:H40-H42",
          "ICD10WHO:H40",
          "ICD10WHO:H40-H42",
          "ICD9:365",
          "ICD9:365.89",
          "ICD9:365.9",
          "MEDGEN:42224",
          "MESH:D005901",
          "NCIT:C26782",
          "SCTID:23986001",
          "UMLS:C0017601",
          "icd11.foundation:499924848"
        ],
        "synonyms": [
          "glaucoma",
          "glaucoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor."
      },
      "child_count": 11,
      "reference_id": "MONDO:0005041"
    }
  ],
  "children": [
    {
      "id": 3346,
      "label": "residual stage of open angle glaucoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7024
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1066",
          "ICD9:365.15",
          "MEDGEN:509733",
          "SCTID:66990007",
          "UMLS:C0154944"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001094"
    },
    {
      "id": 8281,
      "label": "low tension glaucoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4268,
        7024
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13544",
          "EFO:1001022",
          "ICD9:365.12",
          "MEDGEN:56263",
          "MESH:D057066",
          "MedDRA:10024931",
          "SCTID:50485007",
          "UMLS:C0152136"
        ],
        "synonyms": [
          "normal tension glaucoma",
          "Glaucomas, Low tension",
          "Glaucomas, normal tension",
          "glaucoma, Low tension",
          "glaucoma, normal tension",
          "low tension Glaucomas",
          "normal tension Glaucomas",
          "tension Glaucomas, Low",
          "tension Glaucomas, normal",
          "tension glaucoma, Low",
          "tension glaucoma, normal"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A form of glaucoma in which chronic optic nerve damage and loss of vision normally attributable to buildup of intraocular pressure occurs despite prevailing conditions of normal intraocular pressure."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006837"
    },
    {
      "id": 9633,
      "label": "glaucoma 1, open angle, P",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7024,
        18318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024617",
          "MEDGEN:854866",
          "MESH:C566748",
          "OMIM:177700",
          "UMLS:C3888338"
        ],
        "synonyms": [
          "glaucoma 1, open angle, P",
          "glaucoma 1, open angle, type P",
          "GLC1P"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008328"
    },
    {
      "id": 12252,
      "label": "glaucoma type 1C",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7024,
        19827
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002484",
          "MEDGEN:356544",
          "OMIM:601682",
          "UMLS:C1866483"
        ],
        "synonyms": [
          "glaucoma 1C, primary open angle",
          "GLC1C",
          "glaucoma 1, primary open angle, C"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0011129"
    },
    {
      "id": 14171,
      "label": "glaucoma 1, open angle, O",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7024,
        18318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024902",
          "MEDGEN:416515",
          "MESH:C567753",
          "OMIM:613100",
          "UMLS:C2751294"
        ],
        "synonyms": [
          "NTF4 open-angle glaucoma",
          "glaucoma 1, open angle, 1O",
          "glaucoma 1, open angle, O",
          "glaucoma 1, open angle, type O",
          "open-angle glaucoma caused by mutation in NTF4",
          "GLC1O"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any open-angle glaucoma in which the cause of the disease is a mutation in the NTF4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013134"
    },
    {
      "id": 19828,
      "label": "juvenile open angle glaucoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7024,
        18318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1068",
          "GARD:0016883",
          "ICD9:365.14",
          "MEDGEN:453382",
          "MedDRA:10064032",
          "Orphanet:98977",
          "SCTID:71111008",
          "UMLS:C2981140"
        ],
        "synonyms": [
          "JOAG",
          "childhood glaucoma (disease)",
          "glaucoma (disease) of childhood",
          "glaucoma of childhood",
          "juvenile glaucoma",
          "paediatric glaucoma (disease)",
          "pediatric glaucoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Juvenile glaucoma (JG) is a rare autosomal dominant open angle glaucoma, characterized by early onset, severe elevation of intra ocular pressure of rapid progression, leading to optic nerve excavation and, when untreated, substantial visual impairment."
      },
      "child_count": 12,
      "reference_id": "MONDO:0020367"
    },
    {
      "id": 24278,
      "label": "OPTN-related open angle glaucoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7024,
        18318
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026277",
          "MEDGEN:87389",
          "OMIM:137760",
          "UMLS:C0339573"
        ],
        "synonyms": [
          "OPTN-related open angle glaucoma",
          "glaucoma 1, open angle, E"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any open angle glaucoma in which the cause of the disease is a mutation in the OPTN gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100553"
    }
  ],
  "roots": [
    {
      "id": 6774,
      "label": "glaucoma"
    }
  ]
}