{
  "id": 7034,
  "label": "otosclerosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005349",
  "properties": {
    "xrefs": [
      "DOID:12185",
      "EFO:0004213",
      "GARD:0027719",
      "HP:0000362",
      "ICD10CM:H80",
      "ICD10WHO:H80",
      "ICD9:387",
      "ICD9:387.8",
      "ICD9:387.9",
      "MEDGEN:10508",
      "MESH:D010040",
      "NCIT:C185242",
      "OMIMPS:166800",
      "Orphanet:2794",
      "SCTID:11543004",
      "UMLS:C0029899",
      "icd11.foundation:1242649410"
    ],
    "synonyms": [
      "otosclerosis",
      "otosclerosis (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0002409",
        "name": "auditory system disorder"
      },
      {
        "ref": "MONDO:0024623",
        "name": "otorhinolaryngologic disease"
      }
    ],
    "definition": "Formation of spongy bone in the labyrinth capsule which can progress toward the stapes (stapedial fixation) or anteriorly toward the cochlea leading to conductive, sensorineural, or mixed hearing loss. Several genes are associated with familial otosclerosis with varied clinical signs."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 11,
  "parents": [
    {
      "id": 4547,
      "label": "inner ear disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4499,
        20423
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2952",
          "EFO:0009672",
          "ICD10CM:H80-H83",
          "MEDGEN:141671",
          "MESH:D007759",
          "NCIT:C27166",
          "SCTID:232297009",
          "UMLS:C0494559"
        ],
        "synonyms": [
          "disease of internal ear",
          "disease or disorder of internal ear",
          "disorder of internal ear",
          "inner Ear disorder",
          "internal Ear disorder",
          "internal ear disease",
          "internal ear disease or disorder",
          "vestibular disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder affecting the inner ear. Causes are inner ear infections, head injuries, and neoplasms (e.g., acoustic schwannoma). Symptoms include dizziness, imbalance, nausea, and vision problems."
      },
      "child_count": 30,
      "reference_id": "MONDO:0002467"
    },
    {
      "id": 18718,
      "label": "hereditary otorhinolaryngologic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        21538
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021935",
          "MEDGEN:1842579",
          "Orphanet:466084",
          "UMLS:C5681130"
        ],
        "synonyms": [
          "genetic otorhinolaryngologic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "An instance of otorhinolaryngologic disease that is caused by a modification of the individual's genome."
      },
      "child_count": 42,
      "reference_id": "MONDO:0018751"
    },
    {
      "id": 22991,
      "label": "inherited auditory system disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4499,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:707712",
          "SCTID:362991006",
          "UMLS:C1285174"
        ],
        "synonyms": [
          "auditory system hereditary disorder",
          "hereditary auditory system disease",
          "inherited auditory system disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          }
        ],
        "definition": "An instance of auditory system disease that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 24,
      "reference_id": "MONDO:0037940"
    }
  ],
  "children": [
    {
      "id": 9475,
      "label": "otosclerosis 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060920",
          "GARD:0024606",
          "MEDGEN:1639517",
          "OMIM:166800",
          "UMLS:C4551901"
        ],
        "synonyms": [
          "OTSC1",
          "otosclerosis 1",
          "OTS"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008164"
    },
    {
      "id": 12682,
      "label": "otosclerosis 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060921",
          "GARD:0024811",
          "MEDGEN:340117",
          "MESH:C565302",
          "OMIM:605727",
          "UMLS:C1854022"
        ],
        "synonyms": [
          "OTSC2",
          "otosclerosis 2"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0011586"
    },
    {
      "id": 13070,
      "label": "otosclerosis 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060922",
          "GARD:0024835",
          "MEDGEN:334054",
          "MESH:C564268",
          "OMIM:608244",
          "UMLS:C1842353"
        ],
        "synonyms": [
          "OTSC3",
          "otosclerosis 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0011999"
    },
    {
      "id": 13114,
      "label": "congenital corneal opacities, cornea guttata, and corectopia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024838",
          "MEDGEN:324911",
          "MESH:C563921",
          "OMIM:608484",
          "UMLS:C1837970"
        ],
        "synonyms": [
          "congenital corneal opacities, cornea guttata, and corectopia",
          "corneal opacities, congenital, with cornea guttata and corectopia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0012046"
    },
    {
      "id": 13187,
      "label": "otosclerosis 5",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060924",
          "GARD:0024844",
          "MEDGEN:325168",
          "MESH:C563858",
          "OMIM:608787",
          "UMLS:C1837422"
        ],
        "synonyms": [
          "OTSC5",
          "otosclerosis 5"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0012121"
    },
    {
      "id": 13736,
      "label": "otosclerosis 4",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060923",
          "GARD:0024883",
          "MEDGEN:369916",
          "MESH:C566914",
          "OMIM:611571",
          "UMLS:C1969046"
        ],
        "synonyms": [
          "OTSC4",
          "otosclerosis 4"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0012696"
    },
    {
      "id": 13737,
      "label": "otosclerosis 7",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060925",
          "GARD:0024884",
          "MEDGEN:409738",
          "MESH:C566913",
          "OMIM:611572",
          "UMLS:C1969044"
        ],
        "synonyms": [
          "OTSC7",
          "otosclerosis 7"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0012697"
    },
    {
      "id": 13837,
      "label": "otosclerosis 8",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060926",
          "GARD:0024888",
          "MEDGEN:436965",
          "MESH:C567421",
          "OMIM:612096",
          "UMLS:C2677515"
        ],
        "synonyms": [
          "OTSC8",
          "otosclerosis 8"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0012797"
    },
    {
      "id": 15269,
      "label": "otosclerosis 10",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060927",
          "GARD:0024981",
          "MEDGEN:854867",
          "OMIM:615589",
          "UMLS:C3888339"
        ],
        "synonyms": [
          "OTSC10",
          "otosclerosis 10"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0014264"
    },
    {
      "id": 25773,
      "label": "otosclerosis 11",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060928",
          "GARD:0026894",
          "MEDGEN:1846918",
          "OMIM:620576",
          "UMLS:C5882715"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0957928"
    },
    {
      "id": 25968,
      "label": "otosclerosis 12",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7034
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027079",
          "MEDGEN:1856162",
          "OMIM:620792",
          "UMLS:C5935610"
        ],
        "categories": [
          {
            "ref": "MONDO:0002409",
            "name": "auditory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0968980"
    }
  ],
  "roots": [
    {
      "id": 4547,
      "label": "inner ear disorder"
    },
    {
      "id": 18718,
      "label": "hereditary otorhinolaryngologic disease"
    },
    {
      "id": 22991,
      "label": "inherited auditory system disease"
    }
  ]
}