{
  "id": 7060,
  "label": "osteonecrosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005380",
  "properties": {
    "xrefs": [
      "DOID:0080008",
      "DOID:10159",
      "EFO:0004259",
      "GARD:0021657",
      "ICD10CM:M87",
      "ICD10WHO:M87",
      "ICD9:732.3",
      "ICD9:733.4",
      "ICD9:733.41",
      "ICD9:733.42",
      "ICD9:733.43",
      "ICD9:733.44",
      "ICD9:733.49",
      "MEDGEN:45249",
      "MESH:D010020",
      "NCIT:C34880",
      "NCIT:C35476",
      "NORD:1537",
      "Orphanet:399158",
      "SCTID:240196003",
      "UMLS:C0029445",
      "icd11.foundation:536467755"
    ],
    "synonyms": [
      "bone necrosis",
      "ischaemic bone disease",
      "ischemic bone disease",
      "osteonecrosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "A none disease characterized by death of bone tissue due to a lack of blood supply."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 7061,
      "label": "bone disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6893
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080001",
          "EFO:0004260",
          "ICD10CM:M80-M85",
          "ICD9:731.8",
          "ICD9:733.99",
          "MEDGEN:14182",
          "MESH:D001847",
          "NANDO:2100291",
          "NANDO:2100293",
          "SCTID:76069003",
          "UMLS:C0005940"
        ],
        "synonyms": [
          "bone element disease",
          "bone element disease or disorder",
          "disease of bone element",
          "disease or disorder of bone element",
          "disorder of bone element",
          "rare bone disease related to a common gene or pathway defect"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Diseases of bones."
      },
      "child_count": 27,
      "reference_id": "MONDO:0005381"
    }
  ],
  "children": [
    {
      "id": 5799,
      "label": "Kummell disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6822,
        7060,
        23502
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6603",
          "GARD:0023745",
          "ICD10CM:M48.3",
          "ICD9:721.7",
          "MEDGEN:508880",
          "SCTID:111232005",
          "UMLS:C0152088"
        ],
        "synonyms": [
          "Kummell's disease",
          "avascular necrosis of a vertebral body",
          "bony vertebral centrum osteonecrosis",
          "osteonecrosis of bony vertebral centrum",
          "traumatic spondylopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A disease that presents as vertebral osteonecrosis typically affecting a thoracic vertebra with compression deformity, intravertebral vacuum cleft, and exaggerated kyphosis weeks to months after a minor traumatic injury."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003940"
    },
    {
      "id": 18453,
      "label": "avascular necrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7060
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021658",
          "MEDGEN:10200",
          "NCIT:C34841",
          "Orphanet:399164",
          "SCTID:397758007",
          "UMLS:C0027543"
        ],
        "synonyms": [
          "AVN",
          "avascular necrosis of bone"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure."
      },
      "child_count": 3,
      "reference_id": "MONDO:0018373"
    },
    {
      "id": 18460,
      "label": "osteochondrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7060
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8125",
          "GARD:0012704",
          "ICD10CM:M42",
          "ICD9:732.6",
          "MEDGEN:18216",
          "MESH:D055034",
          "NCIT:C34879",
          "Orphanet:399319",
          "SCTID:19579005",
          "UMLS:C0029429",
          "icd11.foundation:1446309782"
        ],
        "synonyms": [
          "osteochondrosis not specified as adult or juvenile, of unspecified site",
          "osteochondritis",
          "osteochondritis juvenilis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A condition that is characterized by defective bone growth that affects the growth centers of bone."
      },
      "child_count": 11,
      "reference_id": "MONDO:0018381"
    },
    {
      "id": 18462,
      "label": "osteonecrosis of genetic origin",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7060
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021667",
          "MEDGEN:1842788",
          "Orphanet:399380",
          "UMLS:C5680035"
        ],
        "synonyms": [
          "bone necrosis of genetic origin",
          "genetic osteonecrosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "An instance of osteonecrosis that is caused by a modification of the individual's genome."
      },
      "child_count": 24,
      "reference_id": "MONDO:0018383"
    },
    {
      "id": 18632,
      "label": "idiopathic phalangeal acro-osteolysis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7060,
        24405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021860",
          "MEDGEN:1803504",
          "Orphanet:444316",
          "UMLS:C5680064"
        ],
        "synonyms": [
          "idiopathic phalangeal acroosteolysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018635"
    },
    {
      "id": 21080,
      "label": "Dieterich disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7060
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000204",
          "MEDGEN:418997",
          "MESH:C536172",
          "UMLS:C2931124"
        ],
        "synonyms": [
          "Dieterich disease",
          "Dieterich's disease",
          "avascular necrosis of the metacarpal head"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0022983"
    },
    {
      "id": 23240,
      "label": "osteoradionecrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7060,
        23212
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025865",
          "MEDGEN:10500",
          "MESH:D010025",
          "NCIT:C63707",
          "SCTID:109333005",
          "UMLS:C0029461"
        ],
        "synonyms": [
          "osteoradionecrosis",
          "Osteoradionecroses",
          "radiation necrosis of bone"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Necrosis of bone following radiation injury."
      },
      "child_count": 2,
      "reference_id": "MONDO:0043735"
    }
  ],
  "roots": [
    {
      "id": 7061,
      "label": "bone disorder"
    }
  ]
}