{
  "id": 7064,
  "label": "focal epilepsy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005384",
  "properties": {
    "xrefs": [
      "DOID:2234",
      "EFO:0004263",
      "ICD9:345.50",
      "MEDGEN:41836",
      "MESH:D004828",
      "NCIT:C122812",
      "SCTID:230381009",
      "UMLS:C0014547"
    ],
    "synonyms": [
      "focal epilepsy",
      "partial epilepsy"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A seizure caused by a localized disorder."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 6761,
      "label": "epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7209
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1826",
          "EFO:0000474",
          "ICD10CM:G40",
          "ICD10WHO:G40",
          "ICD9:345",
          "ICD9:345.8",
          "ICD9:345.80",
          "ICD9:345.9",
          "ICD9:345.90",
          "ICD9:345.91",
          "MEDGEN:4506",
          "MESH:D004827",
          "NCIT:C3020",
          "SCTID:84757009",
          "UMLS:C0014544",
          "birnlex:12718"
        ],
        "synonyms": [
          "epilepsy",
          "seizure disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions."
      },
      "child_count": 13,
      "reference_id": "MONDO:0005027"
    }
  ],
  "children": [
    {
      "id": 4663,
      "label": "frontal lobe epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7064
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3331",
          "MEDGEN:39074",
          "MESH:D017034",
          "SCTID:230394006",
          "UMLS:C0085541"
        ],
        "synonyms": [
          "epilepsy of frontal lobe",
          "frontal lobe epilepsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A localization-related (focal) form of epilepsy characterized by seizures which arise in the frontal lobe. A variety of clinical syndromes exist depending on the exact location of the seizure focus. Frontal lobe seizures may be idiopathic (cryptogenic) or caused by an identifiable disease process such as traumatic injuries, neoplasms, or other macroscopic or microscopic lesions of the frontal lobes (symptomatic frontal lobe seizures). (From Adams et al., Principles of Neurology, 6th ed, pp318-9)"
      },
      "child_count": 2,
      "reference_id": "MONDO:0002612"
    },
    {
      "id": 5231,
      "label": "simple partial epilepsy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7064
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5129",
          "ICD9:345.51"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0003290"
    },
    {
      "id": 8171,
      "label": "complex partial epilepsy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7064
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12382",
          "EFO:1000877",
          "ICD9:345.40",
          "MEDGEN:43169",
          "MESH:D017029",
          "SCTID:407675009",
          "UMLS:C0085417"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and automatism may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0006710"
    },
    {
      "id": 8329,
      "label": "partial motor epilepsy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7064
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3327",
          "EFO:1001089",
          "ICD9:780.39",
          "MEDGEN:5237",
          "MESH:D020938",
          "SCTID:128612007",
          "UMLS:C0016399"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A simple partial seizure consisting of clonus or spasm of a muscle or muscle group; it may be single or in a continuous and repetitive series or may spread to adjacent muscles."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006891"
    },
    {
      "id": 8330,
      "label": "partial sensory epilepsy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7064
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3330",
          "MEDGEN:107460",
          "MESH:D020937",
          "UMLS:C0544645"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder characterized by recurrent focal onset seizures which have sensory (i.e., olfactory, visual, tactile, gustatory, or auditory) manifestations. Partial seizures that feature alterations of consciousness are referred to as complex partial seizures (epilepsy, complex partial)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006892"
    },
    {
      "id": 17942,
      "label": "familial partial epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7064,
        19725,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002173",
          "MEDGEN:1826100",
          "Orphanet:309",
          "UMLS:C5680862"
        ],
        "synonyms": [
          "familial focal epilepsy",
          "hereditary partial epilepsy",
          "epilepsy, partial, familial"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An instance of partial epilepsy that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 21,
      "reference_id": "MONDO:0017704"
    },
    {
      "id": 24297,
      "label": "combined generalized and focal epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7064,
        24298
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1836943",
          "UMLS:C5816884"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any epilepsy where patients have both generalized and focal seizure types, with interictal and/or ictal EEG findings that accompany both seizure types. Patients with Dravet syndrome and Lennox-Gastaut syndrome may have combined focal and generalized epilepsy."
      },
      "child_count": 2,
      "reference_id": "MONDO:0100573"
    },
    {
      "id": 25076,
      "label": "variable-age onset focal epilepsy syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7064,
        24339
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027391"
        ],
        "synonyms": [
          "VAOFAS"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An epilepsy syndrome characterized by focal seizures where age at seizure onset varies."
      },
      "child_count": 8,
      "reference_id": "MONDO:0800492"
    },
    {
      "id": 25086,
      "label": "childhood-onset self-limited focal epilepsy syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7064,
        19725
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027305"
        ],
        "synonyms": [
          "childhood-onset SeLFE"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of conditions characterized by age-dependent occurrence in otherwise normal children. Cognition and neurological evaluation are typically normal. Remission occurs in almost all patients by puberty. Presumed genetic factors have an important role. Seizure semiology and electroencephalographic (EEG) features are specific for each of the syndromes included in this group."
      },
      "child_count": 8,
      "reference_id": "MONDO:0800502"
    }
  ],
  "roots": [
    {
      "id": 6761,
      "label": "epilepsy"
    }
  ]
}