{
  "id": 7075,
  "label": "goiter",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005397",
  "properties": {
    "xrefs": [
      "DOID:12176",
      "EFO:0004283",
      "HP:0000853",
      "ICD9:240.9",
      "MEDGEN:42270",
      "MESH:D006042",
      "NCIT:C26785",
      "SCTID:3716002",
      "UMLS:C0018021"
    ],
    "synonyms": [
      "Thyromegaly",
      "goiter",
      "goiter (disease)",
      "goitre (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 5187,
      "label": "thyroid gland disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:50",
          "EFO:1000627",
          "ICD10CM:E00-E07",
          "ICD9:240-246",
          "ICD9:246.8",
          "ICD9:246.9",
          "MEDGEN:1378579",
          "MESH:D013959",
          "NCIT:C26893",
          "SCTID:14304000",
          "UMLS:C4317107",
          "Wikipedia:Thyroid_disease"
        ],
        "synonyms": [
          "disease of thyroid gland",
          "disease or disorder of thyroid gland",
          "disorder of thyroid gland",
          "thyroid disease",
          "thyroid gland disease",
          "thyroid gland disease or disorder",
          "thyroid gland diseases",
          "thyroid gland disorder",
          "thyroid gland disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease involving the thyroid gland."
      },
      "child_count": 12,
      "reference_id": "MONDO:0003240"
    }
  ],
  "children": [
    {
      "id": 3354,
      "label": "toxic diffuse goiter",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6233,
        7075
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10719",
          "ICD10CM:E05.0",
          "ICD9:242.00",
          "MEDGEN:488851",
          "SCTID:267374005",
          "UMLS:C0342122"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0001104"
    },
    {
      "id": 3675,
      "label": "dyshormonogenic goiter",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7075
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12175",
          "ICD9:246.1",
          "MEDGEN:508873",
          "SCTID:190304001",
          "UMLS:C0152077"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001460"
    },
    {
      "id": 3854,
      "label": "nontoxic goiter",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7075
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13195",
          "MEDGEN:113172",
          "NCIT:C35271",
          "UMLS:C0221777"
        ],
        "synonyms": [
          "euthyroid goiter",
          "euthyroid goitre",
          "non-toxic goiter",
          "non-toxic simple goiter",
          "nontoxic goiter"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Sporadic enlargement of the thyroid gland that is not associated with changes in thyroid function or malignancy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001658"
    },
    {
      "id": 8199,
      "label": "endemic goiter",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7075,
        8312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13198",
          "EFO:1000916",
          "MEDGEN:5357",
          "MESH:D006043",
          "MedDRA:10068848",
          "NCIT:C35023",
          "SCTID:56805008",
          "UMLS:C0018022"
        ],
        "synonyms": [
          "iodine-deficiency-related endemic goiter",
          "simple goiter"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Thyroid gland enlargement caused by inadequate dietary iodine intake. It occurs in areas in which the soil lacks iodine compounds or there is low seafood consumption."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006742"
    },
    {
      "id": 8277,
      "label": "lingual goiter",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7075
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13196",
          "ICD9:759.2",
          "MEDGEN:75766",
          "MESH:D047268",
          "SCTID:75667007",
          "UMLS:C0271760"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Pathological enlargement of the lingual thyroid, ectopic thyroid tissue at the base of the tongue. It may cause upper airway obstruction; dysphagia; or hypothyroidism symptoms."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006833"
    },
    {
      "id": 8310,
      "label": "nodular goiter",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7075
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13197",
          "EFO:1001062",
          "HP:0005994",
          "MEDGEN:42271",
          "MESH:D006044",
          "MedDRA:10018495",
          "NCIT:C131437",
          "SCTID:419153005",
          "UMLS:C0018023"
        ],
        "synonyms": [
          "goiter, nodular",
          "nodular goiter",
          "nodular goiter (disease)",
          "nodular goitre (disease)",
          "nodular goitre NOS"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones."
      },
      "child_count": 1,
      "reference_id": "MONDO:0006869"
    },
    {
      "id": 8410,
      "label": "substernal goiter",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7075
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13200",
          "MEDGEN:9066",
          "MESH:D006045",
          "SCTID:66392007",
          "UMLS:C0018024"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An enlarged thyroid gland with at least 50% of the gland situated behind the sternum. It is an unusual presentation of an intrathoracic goiter. Substernal goiters frequently cause compression on the trachea leading to deviation, narrowing, and respiratory symptoms."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006986"
    }
  ],
  "roots": [
    {
      "id": 5187,
      "label": "thyroid gland disorder"
    }
  ]
}