{
  "id": 7093,
  "label": "hypothyroidism",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005420",
  "properties": {
    "xrefs": [
      "DOID:1459",
      "EFO:0004705",
      "ICD9:244.9",
      "MEDGEN:6991",
      "MESH:D007037",
      "NANDO:2100120",
      "NCIT:C26800",
      "SCTID:40930008",
      "UMLS:C0020676",
      "icd11.foundation:1722092627"
    ],
    "synonyms": [
      "hypothyroidism",
      "underactive thyroid",
      "hypothyroid"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Abnormally low levels of thyroid hormone."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 5187,
      "label": "thyroid gland disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:50",
          "EFO:1000627",
          "ICD10CM:E00-E07",
          "ICD9:240-246",
          "ICD9:246.8",
          "ICD9:246.9",
          "MEDGEN:1378579",
          "MESH:D013959",
          "NCIT:C26893",
          "SCTID:14304000",
          "UMLS:C4317107",
          "Wikipedia:Thyroid_disease"
        ],
        "synonyms": [
          "disease of thyroid gland",
          "disease or disorder of thyroid gland",
          "disorder of thyroid gland",
          "thyroid disease",
          "thyroid gland disease",
          "thyroid gland disease or disorder",
          "thyroid gland diseases",
          "thyroid gland disorder",
          "thyroid gland disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease involving the thyroid gland."
      },
      "child_count": 12,
      "reference_id": "MONDO:0003240"
    }
  ],
  "children": [
    {
      "id": 4160,
      "label": "postsurgical hypothyroidism",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7093
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1458",
          "ICD9:244.0",
          "MEDGEN:509534",
          "SCTID:27059002",
          "UMLS:C0154157"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0002002"
    },
    {
      "id": 5212,
      "label": "iodine hypothyroidism",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7093
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5083",
          "ICD9:244.2",
          "MEDGEN:509535",
          "SCTID:190279008",
          "UMLS:C0154159"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0003271"
    },
    {
      "id": 10931,
      "label": "myxedema",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7093
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11634",
          "EFO:1001055",
          "MEDGEN:6506",
          "MESH:D009230",
          "MedDRA:10028663",
          "NCIT:C34834",
          "OMIM:255900",
          "SCTID:43153006",
          "UMLS:C0027145"
        ],
        "synonyms": [
          "myxedema"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A condition characterized by severe hypothyroidism that is caused by autoimmune thyroid gland disorders, surgical reduction of thyroid tissue, radiation exposure, and viral infections. Signs and symptoms include generalized fatigue, lethargy, increased body weight, pale, edematous and thickened skin, low blood pressure, constipation and cold intolerance."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009718"
    },
    {
      "id": 18613,
      "label": "congenital hypothyroidism",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7093
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050328",
          "GARD:0001487",
          "ICD9:243",
          "ICD9:269.3",
          "ICD9:759.89",
          "MEDGEN:41344",
          "MESH:D003409",
          "MedDRA:10010510",
          "NANDO:2200333",
          "NCIT:C26734",
          "Orphanet:442",
          "SCTID:190268003",
          "SCTID:217710005",
          "UMLS:C0010308",
          "icd11.foundation:602450215"
        ],
        "synonyms": [
          "congenital hypothyroidism",
          "congenital iodine deficiency syndrome",
          "congenital goiter",
          "congenital goitre",
          "congenital hypothyroidism not due to iodine deficiency",
          "cretinism",
          "fetal iodine deficiency syndrome",
          "foetal iodine deficiency syndrome",
          "infantile hypothyroidism"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A thyroid hormone deficiency present from birth."
      },
      "child_count": 8,
      "reference_id": "MONDO:0018612"
    },
    {
      "id": 26522,
      "label": "myxedema coma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7093
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:536791",
          "UMLS:C0238298"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare complication of hypothyroidism characterized by altered mental status, hypothermia, and symptoms related to the slowing of other organ systems."
      },
      "child_count": 0,
      "reference_id": "MONDO:1010100"
    },
    {
      "id": 26530,
      "label": "myxedema heart disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7093
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:526137",
          "UMLS:C0221048"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare complication of hypothyroidism characterized by unexplained heart failure refractory to conventional treatment."
      },
      "child_count": 0,
      "reference_id": "MONDO:1010108"
    }
  ],
  "roots": [
    {
      "id": 5187,
      "label": "thyroid gland disorder"
    }
  ]
}