{
  "id": 7121,
  "label": "primitive neuroectodermal tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005462",
  "properties": {
    "xrefs": [
      "DOID:171",
      "EFO:0005235",
      "ICDO:9473/3",
      "ICDO:9503/3",
      "MEDGEN:64627",
      "MESH:D017599",
      "NCIT:C3716",
      "ONCOTREE:PNET",
      "UMLS:C0206663"
    ],
    "synonyms": [
      "PNET",
      "neuroectodermal neoplasm",
      "neuroectodermal tumor",
      "neuroectodermal tumour",
      "primitive neuroectodermal neoplasm",
      "primitive neuroectodermal tumor",
      "primitive neuroectodermal tumor (PNET)",
      "primitive neuroectodermal tumour (PNET)",
      "neuroepithelioma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A malignant neoplasm that originates in the neuroectoderm. The neuroectoderm constitutes the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems and includes some glial cell precursors."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 7212,
      "label": "embryonal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:688",
          "EFO:0005784",
          "MEDGEN:45034",
          "NCIT:C3264",
          "ONCOTREE:EMBT",
          "UMLS:C0027654"
        ],
        "synonyms": [
          "embryonal neoplasm",
          "embryonal tumor",
          "embryonal tumour",
          "EMBT",
          "embryonal cancer"
        ],
        "definition": "A usually malignant neoplasm composed of primitive (immature) tissues that resemble fetal tissues. Medulloblastoma, Ependymoblastoma, Pineoblastoma, and Wilms tumor are representative embryonal neoplasms. --2003"
      },
      "child_count": 12,
      "reference_id": "MONDO:0005564"
    },
    {
      "id": 20418,
      "label": "neuroepithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:60215",
          "MESH:D018302",
          "NCIT:C3787",
          "ONCOTREE:PRNET",
          "UMLS:C0206715"
        ],
        "synonyms": [
          "neoplasm of neuroepithelial tissue",
          "neoplasm of neuroepithelium",
          "neoplasm of the neuroepithelium",
          "neuroepithelial neoplasm",
          "neuroepithelial neoplasms",
          "neuroepithelial tissue neoplasm",
          "neuroepithelial tissue tumor",
          "neuroepithelial tissue tumour",
          "neuroepithelial tumor",
          "neuroepithelial tumors",
          "neuroepithelial tumour",
          "neuroepithelial tumours",
          "tumor of neuroepithelial tissue",
          "tumor of neuroepithelium",
          "tumor of the neuroepithelium",
          "tumour of neuroepithelial tissue",
          "tumour of neuroepithelium",
          "tumour of the neuroepithelium",
          "primary neuroepithelial tumor",
          "primary neuroepithelial tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neoplasm of the nervous system that arises from the neuroepithelial tissues. Representative examples include astrocytic tumors, oligodendroglial tumors, ependymal tumors, and primitive neuroectodermal tumors."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021193"
    }
  ],
  "children": [
    {
      "id": 3043,
      "label": "central nervous system primitive neuroectodermal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        7121
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060103",
          "GARD:0027536",
          "MEDGEN:854517",
          "NANDO:2200099",
          "NANDO:2200100",
          "NCIT:C5398",
          "UMLS:C3887678",
          "icd11.foundation:1711526170"
        ],
        "synonyms": [
          "CNS PNET",
          "CNS primitive neuroectodermal neoplasm",
          "CNS primitive neuroectodermal tumor",
          "CNS primitive neuroectodermal tumour",
          "central nervous system PNET",
          "central nervous system neuroectodermal tumor",
          "central nervous system neuroectodermal tumour",
          "central nervous system primitive neuroectodermal neoplasm",
          "central nervous system primitive neuroectodermal tumor",
          "central nervous system primitive neuroectodermal tumor (WHO grade IV)",
          "central nervous system primitive neuroectodermal tumour",
          "central nervous system primitive neuroectodermal tumour (WHO grade IV)",
          "central primitive neuroectodermal neoplasm",
          "central primitive neuroectodermal tumor",
          "central primitive neuroectodermal tumour",
          "primitive neuroectodermal tumor of central nervous system",
          "primitive neuroectodermal tumour of central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neuroectodermal tumor that involves the central nervous system."
      },
      "child_count": 16,
      "reference_id": "MONDO:0000640"
    },
    {
      "id": 4215,
      "label": "melanotic neuroectodermal tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7121
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:166",
          "ICDO:9363/0",
          "MEDGEN:60073",
          "MESH:D017600",
          "NCIT:C3717",
          "SCTID:404042005",
          "UMLS:C0206094"
        ],
        "synonyms": [
          "MNTI",
          "infantile melanotic neuroectodermal neoplasm",
          "melanotic Progonoma",
          "melanotic neuroectodermal tumor (morphologic abnormality)",
          "melanotic neuroectodermal tumor of infancy",
          "melanotic neuroectodermal tumor of infancy (morphologic abnormality)",
          "melanotic neuroectodermal tumour (morphologic abnormality)",
          "melanotic neuroectodermal tumour of infancy (morphologic abnormality)",
          "pigmented neuroectodermal tumor",
          "pigmented neuroectodermal tumor of infancy",
          "pigmented neuroectodermal tumour",
          "retinal anlage neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare neoplasm usually occurring in infants. It is characterized by the presence of a mixture of melanin-containing epithelial cells and smaller neuroblast-like cells. It may involve the skull and facial bones, or the epididymis. It usually has a benign clinical course."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002072"
    },
    {
      "id": 7851,
      "label": "neuroblastic tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7121
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000393",
          "MEDGEN:233228",
          "NCIT:C6963",
          "UMLS:C1334953"
        ],
        "synonyms": [
          "neuroblastic tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of nervous system tumors which display neuronal differentiation. It includes tumors that are composed of immature round cells and tumors that display advanced differentiation and the formation of ganglion cells."
      },
      "child_count": 3,
      "reference_id": "MONDO:0006316"
    },
    {
      "id": 16827,
      "label": "primitive neuroectodermal tumor of the corpus uteri",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7121,
        20461
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020478",
          "MEDGEN:1640822",
          "Orphanet:213630",
          "UMLS:C4707724"
        ],
        "synonyms": [
          "body of uterus primitive neuroectodermal tumor",
          "body of uterus primitive neuroectodermal tumour",
          "malignant peripheral neuroectodermal tumor of the corpus uteri",
          "malignant peripheral neuroectodermal tumour of the corpus uteri",
          "peripheral neuroectodermal cancer of the corpus uteri",
          "primitive neuroectodermal tumor of body of uterus",
          "primitive neuroectodermal tumour of body of uterus"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A primitive neuroectodermal tumor that involves the body of uterus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016263"
    },
    {
      "id": 18390,
      "label": "peripheral primitive neuroectodermal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7121,
        20283,
        20329
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017601",
          "ICDO:9364/3",
          "MEDGEN:151926",
          "NANDO:2200054",
          "NANDO:2200055",
          "NCIT:C9341",
          "Orphanet:370348",
          "UMLS:C0684337"
        ],
        "synonyms": [
          "PPNET",
          "pPNET",
          "peripheral PNET",
          "peripheral neuroectodermal neoplasm",
          "peripheral neuroectodermal tumor",
          "peripheral neuroectodermal tumour",
          "peripheral neuroepithelioma",
          "peripheral primitive neuroectodermal neoplasm",
          "peripheral primitive neuroectodermal tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A small round cell tumor with neural differentiation arising from the soft tissues or bone."
      },
      "child_count": 9,
      "reference_id": "MONDO:0018271"
    }
  ],
  "roots": [
    {
      "id": 7212,
      "label": "embryonal neoplasm"
    },
    {
      "id": 20418,
      "label": "neuroepithelial neoplasm"
    }
  ]
}