{
  "id": 7131,
  "label": "temporomandibular joint disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005473",
  "properties": {
    "xrefs": [
      "EFO:0005279",
      "ICD9:524.60",
      "ICD9:524.69",
      "MEDGEN:21092",
      "MESH:D013705",
      "NCIT:C63709",
      "SCTID:41888000",
      "UMLS:C0039494"
    ],
    "synonyms": [
      "TMD"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Any condition affecting the anatomic and functional characteristics of the temporomandibular joint."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 8264,
      "label": "arthropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6893
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:381",
          "EFO:1000999",
          "ICD9:711",
          "ICD9:716.80",
          "ICD9:716.88",
          "ICD9:716.9",
          "ICD9:716.90",
          "ICD9:716.98",
          "ICD9:719.80",
          "ICD9:719.88",
          "ICD9:719.89",
          "ICD9:719.9",
          "ICD9:719.90",
          "ICD9:719.98",
          "MEDGEN:7190",
          "MESH:D007592",
          "MedDRA:10003285",
          "NCIT:C35760",
          "SCTID:399269003",
          "UMLS:C0022408"
        ],
        "synonyms": [
          "Joint disorder",
          "arthropathy",
          "disease of skeletal joint",
          "disease or disorder of skeletal joint",
          "disorder of skeletal joint",
          "disorder, Joint",
          "skeletal joint disease",
          "skeletal joint disease or disorder",
          "Joint ankylosis of the ankle and foot",
          "Joint ankylosis of the forearm",
          "Joint ankylosis of the hand",
          "Joint ankylosis of the lower leg",
          "Joint ankylosis of the pelvic region and thigh",
          "Joint ankylosis of the shoulder region",
          "Joint ankylosis of the upper arm",
          "ankylosis of ankle and foot joint",
          "ankylosis of forearm joint",
          "ankylosis of hand joint",
          "ankylosis of joint of multiple sites",
          "ankylosis of joint of pelvic region and thigh",
          "ankylosis of joint of shoulder region",
          "ankylosis of lower leg joint",
          "ankylosis of multiple joints",
          "ankylosis of upper arm joint",
          "infectious arthropathy",
          "arthrosis",
          "disorder of joint",
          "joint disease",
          "joint disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Any disorder of the joints."
      },
      "child_count": 24,
      "reference_id": "MONDO:0006816"
    }
  ],
  "children": [
    {
      "id": 16803,
      "label": "congenital temporomandibular joint ankylosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4373,
        7131
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020450",
          "MEDGEN:1638477",
          "Orphanet:210576",
          "SCTID:763215008",
          "UMLS:C4706319"
        ],
        "synonyms": [
          "congenital trismus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Congenital temporomandibular joint ankylosis is a rare maxillofacial disorder characterized by significant reduction in mouth opening (i.e. from a few millimeters to a few centimeters) in the absence of acquired factors (e.g. trauma, infection) contributing to the ankylosis. It is associated with variable degrees of facial dysmorphism (i.e. lateral deviation of the mandible and chin, lower facial asymmetry, retrognathia, micrognathia, dental malocclusion) and patients typically present with feeding and breathing difficulties. Developmental delay, hypotonia, seizures, and additional dysmorphic features (e.g. pectus excavatum, low-set ears, hypoplastic alae nasi) have also been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016220"
    },
    {
      "id": 18744,
      "label": "primary condylar hyperplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7131
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021966",
          "MEDGEN:1799993",
          "Orphanet:477781",
          "UMLS:C5568570"
        ],
        "synonyms": [
          "type 1 condylar hyperplasia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018793"
    },
    {
      "id": 20770,
      "label": "temporomandibular joint dysfunction syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        7131,
        8304
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:21093",
          "MESH:D013706",
          "NCIT:C35066",
          "UMLS:C0039496"
        ],
        "synonyms": [
          "temporomandibular joint dysfunction syndrome",
          "Costen Syndrome",
          "Costen's Syndrome",
          "Costen's complex",
          "Costen's syndrome",
          "Costens Syndrome",
          "Joint Syndrome, Temporomandibular",
          "Mandibular dysfunction",
          "Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint",
          "Myofascial pain - dysfunction syndrome of TMJ",
          "Snapping jaw",
          "Syndrome, Costen's",
          "Syndrome, TMJ",
          "Syndrome, Temporomandibular Joint",
          "TMJ Syndrome",
          "TMJ syndrome",
          "TMJPDS - Temporomandibular joint pain dysfunction syndrome",
          "Temporomandibular Joint Dysfunction Syndrome",
          "Temporomandibular Joint Syndrome",
          "Temporomandibular joint pain dysfunction syndrome",
          "Temporomandibular joint syndrome",
          "Temporomandibular joint-pain-dysfunction syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A common disorder noted with jaw movement. It may be caused by malocclusion, repetitive use injury, trauma or arthritis. It is more prevalent among females between their second and fourth decades. Clinical signs include preauricular pain, temporomandibular joint clicking (as the mandibular condyle slips from the articulation made with the capsular disk and temporal bone) and restriction of jaw motion. Clinical course is typically benign but may progress to associated headaches, ear and neck pain, tinnitus and dislocation of temporomandibular joint. Prognosis is favorable as a majority of cases will respond to conservative management."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021895"
    }
  ],
  "roots": [
    {
      "id": 8264,
      "label": "arthropathy"
    }
  ]
}