{
  "id": 7160,
  "label": "diphtheria",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005504",
  "properties": {
    "xrefs": [
      "DOID:11405",
      "EFO:0005549",
      "GARD:0001875",
      "ICD10CM:A36",
      "ICD10WHO:A36",
      "ICD9:032",
      "ICD9:032.9",
      "MEDGEN:4334",
      "MESH:D004165",
      "MedDRA:10013023",
      "NCIT:C34541",
      "Orphanet:1679",
      "SCTID:397428000",
      "UMLS:C0012546",
      "icd11.foundation:508032285"
    ],
    "definition": "A Gram-positive bacterial infection caused by Corynebacterium diphtheriae. It usually involves the oral cavity, pharynx, and nasal cavity. Patients develop pseudomembranes in the affected areas and manifest signs and symptoms of an upper respiratory infection. The diphtheria toxin may cause myocarditis, polyneuritis, and other systemic effects."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 2837,
      "label": "primary bacterial infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050338"
        ]
      },
      "child_count": 37,
      "reference_id": "MONDO:0000314"
    }
  ],
  "children": [
    {
      "id": 3692,
      "label": "cutaneous diphtheria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4929,
        7160,
        20419,
        21329
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12275",
          "GARD:0022952",
          "ICD10CM:A36.3",
          "ICD9:032.85",
          "MEDGEN:41599",
          "NCIT:C34544",
          "SCTID:18901009",
          "UMLS:C0012555",
          "icd11.foundation:618920860"
        ],
        "synonyms": [
          "cutaneous diphtheria"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A usually mild form of diphtheria characterized by infection of the skin by corynebacterium diphtheria and the resulting formation of a chronic, shallow ulcer that is sometimes bordered or followed by a bulla."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001479"
    },
    {
      "id": 20222,
      "label": "anterior nasal diphtheria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7160
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025258",
          "ICD9:032.2",
          "MEDGEN:41598",
          "NCIT:C34542",
          "SCTID:15682004",
          "UMLS:C0012553"
        ],
        "synonyms": [
          "anterior nasal diphtheria",
          "Anterior Nasal Diphtheria",
          "Anterior nasal diphtheria"
        ],
        "definition": "Infection of the anterior nasal structures by Corynebacterium diphtheriae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020838"
    },
    {
      "id": 20225,
      "label": "pseudomembranous diphtheritic conjunctivitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3457,
        7160
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025259",
          "ICD9:032.81",
          "MEDGEN:3856",
          "NCIT:C34543",
          "SCTID:7773002",
          "UMLS:C0012554"
        ],
        "synonyms": [
          "conjunctival diphtheria",
          "pseudomembranous diphtheritic conjunctivitis",
          "Conjunctival diphtheria"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Pseudomembranous colitis resulting from infection by Corynebacterium diphtheriae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020843"
    },
    {
      "id": 20240,
      "label": "faucial diphtheria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7160
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025265",
          "ICD9:032.0",
          "MEDGEN:3857",
          "NCIT:C34545",
          "SCTID:3419005",
          "UMLS:C0012556"
        ],
        "synonyms": [
          "faucial diphtheria",
          "Diphtheritic membrane",
          "Diphtheritic membranous angina",
          "Faucial Diphtheria",
          "Faucial diphtheria",
          "diphtheritic membrane",
          "diphtheritic membranous angina"
        ],
        "definition": "Infection of the fauces by Corynebacterium diphtheriae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020860"
    },
    {
      "id": 20241,
      "label": "laryngeal diphtheria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6195,
        7160,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025266",
          "ICD10CM:A36.2",
          "ICD9:032.3",
          "MEDGEN:4336",
          "NCIT:C34546",
          "SCTID:50215002",
          "UMLS:C0012557",
          "icd11.foundation:1101542926"
        ],
        "synonyms": [
          "laryngeal diphtheria",
          "Diphtheritic laryngotracheitis",
          "Laryngeal Diphtheria",
          "Laryngeal diphtheria",
          "diphtheritic laryngotracheitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Infection of the larynx by Corynebacterium diphtheriae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020863"
    },
    {
      "id": 20242,
      "label": "nasopharyngeal diphtheria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6581,
        7160,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025267",
          "ICD10CM:A36.1",
          "ICD9:032.1",
          "MEDGEN:4337",
          "NCIT:C34547",
          "SCTID:75589004",
          "UMLS:C0012558"
        ],
        "synonyms": [
          "nasopharyngeal diphtheria",
          "Nasopharyngeal Diphtheria",
          "Nasopharyngeal diphtheria"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Infection of the nasopharynx by Corynebacterium diphtheriae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020866"
    },
    {
      "id": 23029,
      "label": "diphtheritic myocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3362,
        7160
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025837",
          "MEDGEN:509091",
          "SCTID:26117009",
          "UMLS:C0152952",
          "icd11.foundation:1165221541"
        ],
        "synonyms": [
          "Corynebacterium diphtheriae caused myocarditis",
          "Corynebacterium diphtheriae myocarditis",
          "diphtheritic myocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An myocarditis caused by infection with Corynebacterium diphtheriae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0041259"
    }
  ],
  "roots": [
    {
      "id": 2837,
      "label": "primary bacterial infectious disease"
    }
  ]
}