{
  "id": 7178,
  "label": "sweat gland carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005524",
  "properties": {
    "xrefs": [
      "DOID:5667",
      "EFO:0005591",
      "ICDO:8400/3",
      "MEDGEN:234685",
      "NCIT:C6938",
      "ONCOTREE:AECA",
      "UMLS:C1412016"
    ],
    "synonyms": [
      "carcinoma of sweat gland",
      "carcinoma of the sweat gland",
      "carcinoma, sweat gland, malignant",
      "sweat gland carcinoma",
      "sweat gland carcinoma/apocrine eccrine carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A carcinoma arising from the sweat glands. Representative examples include tubular carcinoma, spiradenocarcinoma, eccrine carcinoma, hidradenocarcinoma, and apocrine carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 4329,
      "label": "sweat gland cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4478,
        4907
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2095",
          "MEDGEN:231171",
          "NCIT:C4810",
          "UMLS:C1321904"
        ],
        "synonyms": [
          "cancer of sweat gland",
          "malignant neoplasm of sweat gland",
          "malignant neoplasm of the sweat gland",
          "malignant sweat gland neoplasm",
          "malignant tumor of sweat gland",
          "malignant tumor of the sweat gland",
          "malignant tumour of sweat gland",
          "malignant tumour of the sweat gland",
          "sweat gland cancer",
          "sweat gland neoplasms, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A malignant neoplasm that affects the sweat glands."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002206"
    },
    {
      "id": 6712,
      "label": "adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-0386",
          "DOID:299",
          "EFO:0000228",
          "ICDO:8140/3",
          "MEDGEN:122",
          "MESH:D000230",
          "NCIT:C2852",
          "ONCOTREE:ADNOS",
          "SCTID:443961001",
          "UMLS:C0001418"
        ],
        "synonyms": [
          "adenocarcinoma",
          "adenocarcinoma NOS (morphologic abnormality)",
          "adenocarcinoma, malignant",
          "adenocarcinoma, no subtype (morphologic abnormality)",
          "adenocarcinomas",
          "ADNOS"
        ],
        "definition": "A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma."
      },
      "child_count": 128,
      "reference_id": "MONDO:0004970"
    },
    {
      "id": 8398,
      "label": "skin appendage carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4406,
        4707
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001183",
          "ICDO:8390/3",
          "MEDGEN:60209",
          "MESH:D018280",
          "MedDRA:10040798",
          "NCIT:C3775",
          "ONCOTREE:SKAC",
          "UMLS:C0206697"
        ],
        "synonyms": [
          "adnexal carcinoma",
          "carcinoma of adnexa",
          "carcinoma of cutaneous appendage",
          "carcinoma of skin appendage",
          "carcinoma, adnexal, malignant",
          "cutaneous appendage carcinoma",
          "skin appendage carcinoma",
          "skin adnexal carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A carcinoma arising from the sebaceous glands, sweat glands, or the hair follicles. Representative examples include sebaceous carcinoma, apocrine carcinoma, eccrine carcinoma, and pilomatrical carcinoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0006973"
    }
  ],
  "children": [
    {
      "id": 5141,
      "label": "cutaneous adenocystic carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6713,
        7178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4871",
          "GARD:0023400",
          "MEDGEN:91071",
          "NCIT:C4471",
          "SCTID:254711000",
          "UMLS:C0346017"
        ],
        "synonyms": [
          "adenoid cystic carcinoma of skin",
          "adenoid cystic carcinoma of the skin",
          "adenoid cystic cutaneous carcinoma",
          "adenoid cystic eccrine carcinoma (morphologic abnormality)",
          "adenoid cystic skin carcinoma",
          "primary cutaneous adenocystic carcinoma",
          "skin of body adenoid cystic carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A adenoid cystic carcinoma that involves the skin of body."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003180"
    },
    {
      "id": 5169,
      "label": "apocrine adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5170,
        7178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4933",
          "GARD:0012138",
          "ICDO:8401/3",
          "MEDGEN:569650",
          "NCIT:C4169",
          "UMLS:C0334346"
        ],
        "synonyms": [
          "apocrine adenocarcinoma (morphologic abnormality)",
          "apocrine carcinoma",
          "apocrine gland adenocarcinoma",
          "apocrine gland carcinoma",
          "carcinoma of apocrine gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A carcinoma with apocrine differentiation arising from the sweat glands. It presents as single or multiple nodular lesions which may be ulcerated or hemorrhagic and is usually in the axilla and less often in the anogenital region. It grows in the dermis and infiltrates subcutaneous tissues. It is characterized by the presence of large cells with abundant eosinophilic cytoplasm and large often vesicular nuclei. Most cases are slow growing tumors and have a prolonged course."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003214"
    },
    {
      "id": 7795,
      "label": "hidradenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6742,
        7178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000295",
          "ICDO:8402/3",
          "MEDGEN:137746",
          "NCIT:C54664",
          "UMLS:C0334344"
        ],
        "synonyms": [
          "clear cell eccrine carcinoma",
          "hidradenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A carcinoma with apocrine and less often eccrine differentiation, arising from the sweat glands. It usually presents as a solitary slow growing nodule in the dermis or subcutaneous tissues. It is characterized by a nodular growth pattern and it is often associated with necrotic changes."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006245"
    },
    {
      "id": 21295,
      "label": "eccrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7162,
        7178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4920",
          "ICDO:8413/3",
          "MEDGEN:690083",
          "NCIT:C27255",
          "SCTID:400173004",
          "UMLS:C1266066"
        ],
        "synonyms": [
          "carcinoma of eccrine sweat gland",
          "carcinoma, eccrine gland, malignant",
          "eccrine adenocarcinoma",
          "eccrine adenocarcinoma (morphologic abnormality)",
          "eccrine carcinoma",
          "eccrine carcinoma of skin",
          "eccrine sweat gland adenocarcinoma",
          "eccrine sweat gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An adenocarcinoma with eccrine differentiation arising from the sweat glands. It includes the following subtypes: ductal eccrine adenocarcinoma, papillary eccrine carcinoma, and eccrine porocarcinoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0024240"
    }
  ],
  "roots": [
    {
      "id": 4329,
      "label": "sweat gland cancer"
    },
    {
      "id": 6712,
      "label": "adenocarcinoma"
    },
    {
      "id": 8398,
      "label": "skin appendage carcinoma"
    }
  ]
}