{
  "id": 7213,
  "label": "blastoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005565",
  "properties": {
    "xrefs": [
      "DOID:0070003",
      "DOID:4766",
      "EFO:0005785",
      "ICDO:8981/3",
      "MEDGEN:181704",
      "NCIT:C8997",
      "UMLS:C0936282"
    ],
    "synonyms": [
      "blastoma",
      "embryoma"
    ],
    "definition": "A malignant neoplasm composed of undifferentiated cells."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 6733,
      "label": "cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050686",
          "DOID:0050687",
          "DOID:162",
          "ICD9:195.8",
          "ICD9:199",
          "ICD9:199.1",
          "ICDO:8000/3",
          "MEDGEN:14297",
          "NCIT:C9305",
          "ONCOTREE:MT",
          "SCTID:363346000",
          "UMLS:C0006826",
          "birnlex:406"
        ],
        "synonyms": [
          "CA",
          "cancer",
          "cell type cancer",
          "malignancy",
          "malignant growth",
          "malignant neoplasm",
          "malignant neoplasm (disease)",
          "malignant neoplastic disease",
          "malignant tumor",
          "malignant tumour",
          "neoplasm (disease), malignant",
          "neoplasm, malignant",
          "MT"
        ],
        "definition": "A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas."
      },
      "child_count": 33,
      "reference_id": "MONDO:0004992"
    },
    {
      "id": 7212,
      "label": "embryonal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:688",
          "EFO:0005784",
          "MEDGEN:45034",
          "NCIT:C3264",
          "ONCOTREE:EMBT",
          "UMLS:C0027654"
        ],
        "synonyms": [
          "embryonal neoplasm",
          "embryonal tumor",
          "embryonal tumour",
          "EMBT",
          "embryonal cancer"
        ],
        "definition": "A usually malignant neoplasm composed of primitive (immature) tissues that resemble fetal tissues. Medulloblastoma, Ependymoblastoma, Pineoblastoma, and Wilms tumor are representative embryonal neoplasms. --2003"
      },
      "child_count": 12,
      "reference_id": "MONDO:0005564"
    }
  ],
  "children": [
    {
      "id": 7531,
      "label": "pulmonary blastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7213,
        7822
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4765",
          "EFO:0007458",
          "GARD:0018864",
          "ICD9:162.9",
          "ICDO:8972/3",
          "MEDGEN:61645",
          "MESH:D018202",
          "NCIT:C3732",
          "Orphanet:64741",
          "SCTID:189815007",
          "UMLS:C0206629"
        ],
        "synonyms": [
          "Pneumoblastoma",
          "blastoma of lung",
          "blastoma of the lung",
          "lung blastoma",
          "pulmonary blastoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A malignant neoplasm of the lung composed of tubular structures and immature mesenchymal elements, which may differentiate towards skeletal and smooth muscle, cartilage or a combination of muscle and cartilage. This is a nodular tumor found in the periphery of the lung. It can occur at any age. The prognosis is related to the stage of the disease at the time of resection. Pulmonary blastoma is divided into two subtypes: epithelial predominant and biphasic."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005933"
    },
    {
      "id": 11906,
      "label": "gonadoblastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4279,
        4375,
        4558,
        7213,
        7464,
        7639
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3301",
          "ICDO:9073/1",
          "MEDGEN:104912",
          "MESH:D018238",
          "NCIT:C3754",
          "ONCOTREE:OGBL",
          "UMLS:C0206661"
        ],
        "synonyms": [
          "gonad blastoma",
          "gonadoblastoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A mixed germ cell/sex cord-stromal tumor characterized by the presence of large germ cells which resemble seminoma cells and small cells which resemble Sertoli or granulosa cells. It occurs in the testis and the ovary and is identified in children and adults. It is often associated with gonadal dysgenesis and abnormal karyotype."
      },
      "child_count": 12,
      "reference_id": "MONDO:0010768"
    },
    {
      "id": 25249,
      "label": "pituitary blastoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4246,
        7213
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081244",
          "GARD:0026634",
          "MEDGEN:1656462",
          "NCIT:C155304",
          "UMLS:C4743978"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A pituitary cancer that is characterized by features of Cushing disease, with elevated blood ACTH levels and hypercortisolism arising within the fetal anterior pituitary and associated with DICER1 mutations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0858916"
    }
  ],
  "roots": [
    {
      "id": 6733,
      "label": "cancer"
    },
    {
      "id": 7212,
      "label": "embryonal neoplasm"
    }
  ]
}