{
  "id": 7216,
  "label": "cholesterol embolism",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005568",
  "properties": {
    "xrefs": [
      "DOID:1461",
      "EFO:0005801",
      "ICD10CM:I75",
      "ICD9:445",
      "ICD9:459.89",
      "MEDGEN:57437",
      "MESH:D017700",
      "SCTID:307406004",
      "UMLS:C0149649"
    ],
    "synonyms": [
      "atheroembolism",
      "purple toe syndrome",
      "trash foot",
      "warfarin blue toe syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Blocking of a blood vessel by cholesterol-rich atheromatous deposits, generally occurring in the flow from a large artery to small arterial branches. It is also called arterial-arterial embolization or atheroembolism which may be spontaneous or iatrogenic. Patients with spontaneous atheroembolism often have painful, cyanotic digits of acute onset."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7065,
      "label": "vascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:178",
          "EFO:0004264",
          "ICD10CM:I00-I99",
          "ICD10CM:I70-I79",
          "ICD9:442.9",
          "MEDGEN:22621",
          "MESH:D014652",
          "NANDO:2100294",
          "NCIT:C35117",
          "SCTID:27550009",
          "UMLS:C0042373"
        ],
        "synonyms": [
          "disease of vasculature",
          "disease or disorder of vasculature",
          "disorder of vasculature",
          "vascular disorder",
          "vasculature disease",
          "vasculature disease or disorder",
          "vasculopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A general term used to describe any disease affecting blood vessels]. It includes vascular abnormalities caused by degenerative, metabolic and inflammatory conditions, embolic diseases, coagulative disorders, and functional disorders such as posteri or reversible encephalopathy syndrome."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005385"
    }
  ],
  "children": [
    {
      "id": 4058,
      "label": "blue toe syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7216
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14121",
          "MEDGEN:66940",
          "MESH:D018438",
          "UMLS:C0242645"
        ],
        "synonyms": [
          "purple toe syndrome",
          "trash foot",
          "warfarin blue toe syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A condition that is caused by recurring atheroembolism in the lower extremities. It is characterized by cyanotic discoloration of the toes, usually the first, fourth, and fifth toes. Discoloration may extend to the lateral aspect of the foot. Despite the gangrene-like appearance, blue toes may respond to conservative therapy without amputation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001883"
    },
    {
      "id": 4161,
      "label": "atheroembolism of kidney",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6948,
        7216
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1460",
          "ICD10CM:I75.81",
          "MEDGEN:541484",
          "UMLS:C0268792"
        ],
        "synonyms": [
          "cholesterol embolism of kidney",
          "kidney cholesterol embolism"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A cholesterol embolism that involves the kidney."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002004"
    }
  ],
  "roots": [
    {
      "id": 7065,
      "label": "vascular disorder"
    }
  ]
}