{
  "id": 7243,
  "label": "malignant epithelioid mesothelioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005599",
  "properties": {
    "xrefs": [
      "DOID:4489",
      "EFO:0006452",
      "GARD:0024208",
      "ICDO:9052/3",
      "MEDGEN:163578",
      "NCIT:C7985",
      "UMLS:C0862312"
    ],
    "synonyms": [
      "epithelial mesothelioma",
      "epithelioid mesothelioma",
      "epithelioid mesothelioma, malignant",
      "epithelioid mesothelioma, malignant (morphologic abnormality)",
      "malignant epithelial mesothelioma"
    ],
    "definition": "A malignant neoplasm arising from mesothelial cells in the pleura. It is characterized by the presence of neoplastic cells with an epithelioid appearance. In the majority of cases, the neoplastic epithelioid cells lack significant cytologic atypia; mitotic figures are infrequently seen. In a minority of cases, the neoplastic cells are poorly differentiated and there is evidence of nuclear atypia and increased mitotic activity."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 7834,
      "label": "malignant mesothelioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        6794
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1790",
          "EFO:1000355",
          "GARD:0007026",
          "HP:0100001",
          "ICD9:199.1",
          "ICDO:9050/3",
          "MEDGEN:91062",
          "MESH:C562839",
          "MedDRA:10027406",
          "NCIT:C4456",
          "OMIM:156240",
          "Orphanet:50251",
          "SCTID:109378008",
          "UMLS:C0345967",
          "icd11.foundation:369414280"
        ],
        "synonyms": [
          "malignant mesothelial tumor",
          "malignant mesothelial tumour",
          "malignant mesothelioma",
          "malignant mesothelioma (disease)",
          "malignant neoplasm of mesothelium",
          "malignant neoplasm of the mesothelium",
          "malignant tumor of mesothelium",
          "malignant tumor of the mesothelium",
          "malignant tumour of mesothelium",
          "malignant tumour of the mesothelium",
          "mesothelioma, malignant",
          "mesothelioma, somatic",
          "advanced malignant mesothelioma",
          "asbestos-related malignant mesothelioma",
          "diffuse malignant mesothelioma",
          "malignant mesothelial neoplasm",
          "MESOM"
        ],
        "definition": "A malignant neoplasm of the pleura or peritoneum, arising from mesothelial cells. It is associated with exposure to asbestos."
      },
      "child_count": 22,
      "reference_id": "MONDO:0006292"
    }
  ],
  "children": [
    {
      "id": 7900,
      "label": "pleural epithelioid mesothelioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6838,
        7243
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000484",
          "GARD:0024387",
          "MEDGEN:318031",
          "NCIT:C45662",
          "UMLS:C1709574"
        ],
        "synonyms": [
          "malignant epithelioid mesothelioma of pleura",
          "pleura malignant epithelioid mesothelioma",
          "pleural epithelioid mesothelioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Malignant mesothelioma that arises from the pleura and is characterized by the presence of cells with epithelioid morphology. The epithelioid cells usually have eosinophilic cytoplasm, bland nuclei, and form tubulopapillary, microglandular, or sheet-like patterns."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006378"
    }
  ],
  "roots": [
    {
      "id": 7834,
      "label": "malignant mesothelioma"
    }
  ]
}