{
  "id": 7247,
  "label": "tubular adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005606",
  "properties": {
    "xrefs": [
      "DOID:4929",
      "EFO:0006500",
      "ICDO:8211/3",
      "MEDGEN:61428",
      "NCIT:C65192",
      "UMLS:C0205645"
    ],
    "synonyms": [
      "carcinoma, tubular cell, malignant",
      "tubular adenocarcinoma",
      "tubular adenocarcinoma (morphologic abnormality)"
    ],
    "definition": "An infiltrating adenocarcinoma in which the malignant cells form tubular structures. Representative examples include the tubular breast carcinoma and the gastric tubular adenocarcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6712,
      "label": "adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-0386",
          "DOID:299",
          "EFO:0000228",
          "ICDO:8140/3",
          "MEDGEN:122",
          "MESH:D000230",
          "NCIT:C2852",
          "ONCOTREE:ADNOS",
          "SCTID:443961001",
          "UMLS:C0001418"
        ],
        "synonyms": [
          "adenocarcinoma",
          "adenocarcinoma NOS (morphologic abnormality)",
          "adenocarcinoma, malignant",
          "adenocarcinoma, no subtype (morphologic abnormality)",
          "adenocarcinomas",
          "ADNOS"
        ],
        "definition": "A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma."
      },
      "child_count": 128,
      "reference_id": "MONDO:0004970"
    }
  ],
  "children": [
    {
      "id": 5795,
      "label": "invasive tubular breast carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6698,
        7247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6587",
          "MEDGEN:230969",
          "NCIT:C9135",
          "UMLS:C1328544"
        ],
        "synonyms": [
          "breast tubular adenocarcinoma",
          "infiltrating tubular breast carcinoma",
          "infiltrating tubular carcinoma of breast",
          "infiltrating tubular carcinoma of the breast",
          "invasive tubular breast carcinoma",
          "invasive tubular carcinoma of breast",
          "invasive tubular carcinoma of the breast",
          "tubular breast cancer",
          "tubular breast carcinoma",
          "tubular carcinoma of breast",
          "tubular carcinoma of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "An invasive adenocarcinoma of the breast with a favorable prognosis. It is composed of tubular structures lined by a single layer of epithelium."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003936"
    },
    {
      "id": 6905,
      "label": "pancreatic ductal adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7247,
        7633
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3498",
          "DOID:3587",
          "EFO:0002517",
          "GARD:0027716",
          "ICD9:157.3",
          "MEDGEN:277490",
          "MESH:D021441",
          "NCIT:C9120",
          "UMLS:C1335302",
          "icd11.foundation:581089833"
        ],
        "synonyms": [
          "ductal adenocarcinoma of pancreas",
          "ductal adenocarcinoma of the pancreas",
          "pancreas ductal adenocarcinoma",
          "pancreas tubular adenocarcinoma",
          "pancreatic duct adenocarcinoma",
          "pancreatic ductal adenocarcinoma",
          "pancreatic ductal carcinoma",
          "pancreatic tubular adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An infiltrating adenocarcinoma that arises from the epithelial cells of the pancreas. It affects males more often than females and the patients are usually over 50 years of age. Microscopically it is characterized by the presence of glandular (ductal) differentiation and desmoplastic stroma formation. Signs and symptoms include pain, loss of weight, and jaundice. It grows rapidly and is usually detected after it has metastasized to other anatomic sites. The prognosis is usually poor."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005184"
    },
    {
      "id": 7621,
      "label": "gastric tubular adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6770,
        7247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6595",
          "EFO:1000030",
          "GARD:0027735",
          "MEDGEN:234303",
          "NCIT:C5473",
          "ONCOTREE:TSTAD",
          "UMLS:C1333791"
        ],
        "synonyms": [
          "gastric tubular adenocarcinoma",
          "stomach tubular adenocarcinoma",
          "tubular adenocarcinoma of stomach",
          "tubular adenocarcinoma of the stomach",
          "tubular stomach adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A variant of gastric adenocarcinoma characterized by prominent dilated or slit-like tubules."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006035"
    },
    {
      "id": 17615,
      "label": "well-differentiated fetal adenocarcinoma of the lung",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6791,
        7247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021120",
          "ICDO:8333/3",
          "MEDGEN:843585",
          "NCIT:C45509",
          "Orphanet:284395",
          "UMLS:C3873372"
        ],
        "synonyms": [
          "WDFA",
          "fetal adenocarcinoma",
          "fetal lung adenocarcinoma",
          "foetal adenocarcinoma",
          "foetal lung adenocarcinoma",
          "pulmonary adenocarcinoma of fetal type",
          "pulmonary adenocarcinoma of foetal type",
          "pulmonary endodermal tumor resembling fetal lung",
          "pulmonary endodermal tumour resembling foetal lung",
          "well-differentiated fetal lung adenocarcinoma",
          "well-differentiated foetal lung adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Well-differentiated fetal adenocarcinoma (WDFA) of the lung is a rare, primary, low-grade, bronchopulmonary neoplasm characterized by a well-circumscribed, usually large, pulmonary mass that is histologically composed of glycogen-rich neoplastic glands and tubules that resemble fetal lungs at 10 to 16 weeks of gestation and benign adjacent stroma. It typically presents with chest pain, cough, dyspnea, hemoptysis and/or generalized, non-specific symptoms, such as night sweats, lethargy, poor appetite and weight loss."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017292"
    }
  ],
  "roots": [
    {
      "id": 6712,
      "label": "adenocarcinoma"
    }
  ]
}