{
  "id": 7308,
  "label": "bone giant cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005674",
  "properties": {
    "xrefs": [
      "DOID:4305",
      "EFO:0007176",
      "GARD:0013046",
      "HP:0011847",
      "MEDGEN:64624",
      "MESH:D018212",
      "NCIT:C121932",
      "ONCOTREE:GCTB",
      "Orphanet:363976",
      "SCTID:697970009",
      "UMLS:C0206638"
    ],
    "synonyms": [
      "GCT of bone",
      "Osteoclastoma, benign",
      "benign bone giant cell tumor",
      "benign bone giant cell tumour",
      "giant cell tumor of bone",
      "giant cell tumor of bone (morphologic abnormality)",
      "giant cell tumor of bone NOS (morphologic abnormality)",
      "giant cell tumor of the bone",
      "giant cell tumor, benign",
      "giant cell tumour of bone (morphologic abnormality)",
      "giant cell tumour of bone NOS (morphologic abnormality)",
      "giant cell tumour of the bone"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A benign but locally aggressive tumor that arises from the bone and is composed of mononuclear cells admixed with macrophages and osteoclast-like giant cells. It usually arises from the ends of long bones or the vertebrae. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 20297,
      "label": "bone sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4262,
        6816
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080639",
          "GARD:0020547",
          "ICD9:170.9",
          "MEDGEN:352831",
          "MedDRA:10006007",
          "NCIT:C9312",
          "Orphanet:223727",
          "SCTID:448710000",
          "UMLS:C1704327"
        ],
        "synonyms": [
          "bone sarcoma",
          "osseous sarcoma",
          "sarcoma of bone",
          "sarcoma of the bone",
          "skeletal sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A sarcoma that arises from the bone. Representative examples are osteosarcoma and chondrosarcoma."
      },
      "child_count": 26,
      "reference_id": "MONDO:0021054"
    }
  ],
  "children": [
    {
      "id": 8223,
      "label": "giant cell reparative granuloma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7308
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1866",
          "EFO:1000950",
          "GARD:0024470",
          "ICD9:526.3",
          "MEDGEN:102385",
          "MESH:D006101",
          "NCIT:C121893",
          "Orphanet:696078",
          "SCTID:15350006",
          "UMLS:C0162375"
        ],
        "synonyms": [
          "GCLSB",
          "central giant cell (reparative) granuloma",
          "central giant cell granuloma",
          "giant cell lesion of small bones"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A rare tumor-like lesion of the hands and feet characterized by the presence of hemorrhagic fibrous tissue, hemosiderin deposition, osteoclast-like giant cells which are irregularly distributed, and reactive bone formation. Pain and swelling are the most frequent symptoms. It may recur following curettage, but is usually cured after a second procedure."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006770"
    }
  ],
  "roots": [
    {
      "id": 20297,
      "label": "bone sarcoma"
    }
  ]
}