{
  "id": 7423,
  "label": "idiopathic CD4-positive T-lymphocytopenia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005807",
  "properties": {
    "xrefs": [
      "DOID:3109",
      "GARD:0024233",
      "MEDGEN:64647",
      "MESH:D018344",
      "NCIT:C84780",
      "UMLS:C0206744"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A rare immunodeficiency syndrome characterized by the decrease of the CD4-positive lymphocytes below 300 per cubic millimeter in the absence of identifiable immunodeficiency causes. Patients with this syndrome are at an increased risk of opportunistic infections."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5659,
      "label": "T-cell immunodeficiency",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20334
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:613",
          "GARD:0005107",
          "MEDGEN:226894",
          "NCIT:C27145",
          "SCTID:402792003",
          "UMLS:C1274233"
        ],
        "synonyms": [
          "T-cell immunodeficiency",
          "T-lymphocyte deficiency (finding)",
          "T-lymphocyte immunodeficiency",
          "T lymphocyte deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A broad classification of disorders that affect the cell-mediated aspect of the immune response. Circulating numbers of T lymphocytes are decreased or ineffective."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003780"
    },
    {
      "id": 5662,
      "label": "lymphopenia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5664
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:614",
          "HP:0001888",
          "ICD10CM:D72.810",
          "ICD9:288.51",
          "ICD9:288.8",
          "MEDGEN:7418",
          "MESH:D008231",
          "SCTID:48813009",
          "UMLS:C0024312",
          "icd11.foundation:298296736"
        ],
        "synonyms": [
          "lymphocytopenia",
          "lymphopenia",
          "lymphopenia (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Reduction in the number of lymphocytes."
      },
      "child_count": 1,
      "reference_id": "MONDO:0003783"
    },
    {
      "id": 24405,
      "label": "idiopathic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29381
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:548250",
          "UMLS:C0277553"
        ],
        "synonyms": [
          "idiopathic disorder"
        ],
        "definition": "A disease or disorder for which the cause is of uncertain or unknown."
      },
      "child_count": 79,
      "reference_id": "MONDO:0700007"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5659,
      "label": "T-cell immunodeficiency"
    },
    {
      "id": 5662,
      "label": "lymphopenia"
    },
    {
      "id": 24405,
      "label": "idiopathic disease"
    }
  ]
}