{
  "id": 7428,
  "label": "influenza",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005812",
  "properties": {
    "xrefs": [
      "DOID:8469",
      "EFO:0007328",
      "ICD9:487",
      "ICD9:487.8",
      "MEDGEN:9466",
      "MESH:D007251",
      "MESH:D009976",
      "NCIT:C53482",
      "SCTID:61700007",
      "UMLS:C0021400",
      "icd11.foundation:145723401"
    ],
    "synonyms": [
      "Influenza with other manifestations",
      "flu",
      "influenza infection",
      "orthomyxoviridae caused disease or disorder",
      "orthomyxoviridae disease or disorder",
      "orthomyxoviridae infectious disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 21376,
      "label": "viral respiratory tract infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6834,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:519.8",
          "MEDGEN:163755",
          "NCIT:C27219",
          "SCTID:312133006",
          "UMLS:C0877203"
        ],
        "synonyms": [
          "viral respiratory tract infection"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A respiratory tract infection caused by a virus. Viruses represent the most common causes of upper and lower respiratory tract infections and include rhinoviruses, influenza viruses, parainfluenza viruses, and respiratory syncytial virus."
      },
      "child_count": 12,
      "reference_id": "MONDO:0024352"
    },
    {
      "id": 24062,
      "label": "primary viral infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6834
      ],
      "type_id": 0,
      "properties": {
        "definition": "The initial viral infectious disase that causes illness."
      },
      "child_count": 32,
      "reference_id": "MONDO:0100329"
    }
  ],
  "children": [
    {
      "id": 7119,
      "label": "swine influenza",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7428
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050211",
          "EFO:0005226",
          "MEDGEN:1385137",
          "NCIT:C80444",
          "SCTID:442696006",
          "UMLS:C0276357"
        ],
        "synonyms": [
          "H1N1 Influenza",
          "H1N1 Virus infection",
          "H1N1 flu",
          "Influenza A (H1N1)",
          "Influenza A (H1N1) Virus infection",
          "Swine influenza virus caused influenza",
          "Swine influenza virus influenza",
          "swine flu"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An acute viral respiratory infection caused by a strain of influenza virus which is endemic in swine (pigs). Rarely reported in humans prior to 2009, the disease is caused by a mutated strain of swine influenza A (H1N1) virus. It is highly contagious and spreads mainly through coughing and sneezing. Signs and symptoms include fever, chills, coughing, sore throat headache, muscle ache, and generalized weakness. Antiviral medications are most effective in the first two days of the illness."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005460"
    },
    {
      "id": 18684,
      "label": "avian influenza",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7428
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4492",
          "EFO:0005222",
          "GARD:0021897",
          "MEDGEN:42091",
          "MESH:D005585",
          "Orphanet:454836",
          "SCTID:55604004",
          "UMLS:C0016627"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Infection of domestic and wild fowl and other birds with influenza A virus. Avian influenza usually does not sicken birds, but can be highly pathogenic and fatal in domestic poultry."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018695"
    }
  ],
  "roots": [
    {
      "id": 21376,
      "label": "viral respiratory tract infection"
    },
    {
      "id": 24062,
      "label": "primary viral infectious disease"
    }
  ]
}