{
  "id": 7463,
  "label": "mitral valve stenosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005852",
  "properties": {
    "xrefs": [
      "DOID:1754",
      "EFO:0007372",
      "MEDGEN:44466",
      "MESH:D008946",
      "NANDO:1200963",
      "NANDO:2200302",
      "NCIT:C50654",
      "SCTID:79619009",
      "UMLS:C0026269",
      "icd11.foundation:2115139779"
    ],
    "synonyms": [
      "mitral stenosis",
      "mitral stenoses",
      "mitral valve stenoses",
      "stenoses, mitral",
      "stenoses, mitral valve",
      "stenosis, mitral",
      "stenosis, mitral valve",
      "valve stenoses, mitral",
      "valve stenosis, mitral"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Narrowing of the left atrioventricular mitral orifice."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5647,
      "label": "mitral valve disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4883
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:61",
          "EFO:0009557",
          "ICD9:394",
          "ICD9:394.1",
          "ICD9:394.9",
          "ICD9:424.0",
          "MEDGEN:7669",
          "NCIT:C78446",
          "SCTID:11851006",
          "UMLS:C0026265",
          "icd11.foundation:1997348476"
        ],
        "synonyms": [
          "disease of mitral valve",
          "disease or disorder of mitral valve",
          "disorder of mitral valve",
          "mitral valve disease",
          "mitral valve disease or disorder",
          "mitral valve disorder",
          "rheumatic disease of mitral valve",
          "rheumatic mitral insufficiency",
          "rheumatic mitral valve changes",
          "rheumatic mitral valve incompetence",
          "rheumatic mitral valve regurgitation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the mitral valve."
      },
      "child_count": 7,
      "reference_id": "MONDO:0003767"
    }
  ],
  "children": [
    {
      "id": 19857,
      "label": "congenital mitral stenosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7463,
        19556,
        23092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0001496",
          "HP:0011570",
          "ICD10CM:Q23.2",
          "ICD9:746.5",
          "MEDGEN:57857",
          "NANDO:1200963",
          "Orphanet:99057",
          "SCTID:82458004",
          "UMLS:C0158618",
          "icd11.foundation:2102952411"
        ],
        "synonyms": [
          "congenital mitral stenosis",
          "congenital mitral stenosis (disease)",
          "congenital mitral valve stenosis",
          "hereditary mitral valve stenosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Congenital mitral stenosis is a congenital heart malformation comprising a spectrum of morphologically heterogeneous developmental anomalies that result in functional and anatomic obstruction of inflow into the left ventricle. The structure of the mitral valve is affected at the level of the supravalvular ring, annulus, leaflets or subvalvar copmponents and include supra-valvular ring, leaflet fusion (intra-leaflet ring), mitral parachute deformity and papillary muscle abnormalities. It may be isolated or associated with other heart malformations. The clinical presentation depends on the degree of obstruction, the presence of regurgitation, the presence and severity of associated pulmonary hypertension, and the presence of associated heart malformations. It may present with symptoms and signs of low cardiac output and right ventricular failure such as pulmonary infections, failure to thrive, exertional dyspnea, cough, cyanosis and congestive heart failure."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020398"
    }
  ],
  "roots": [
    {
      "id": 5647,
      "label": "mitral valve disorder"
    }
  ]
}