{
  "id": 7479,
  "label": "nervous system cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005872",
  "properties": {
    "xrefs": [
      "DOID:3093",
      "EFO:0007392",
      "ICD9:192",
      "ICD9:192.8",
      "ICD9:192.9",
      "MEDGEN:99231",
      "MESH:D009423",
      "NCIT:C4788",
      "SCTID:372063002",
      "UMLS:C0497549"
    ],
    "synonyms": [
      "nervous system neoplasm",
      "neural neoplasm",
      "neural tumor",
      "neural tumour",
      "tumor of the nervous system",
      "tumour of the nervous system",
      "cancer of nervous system",
      "malignant neoplasm of nervous system",
      "malignant neoplasm of the nervous system",
      "malignant nervous system neoplasm",
      "malignant nervous system tumor",
      "malignant nervous system tumour",
      "malignant tumor of nervous system",
      "malignant tumor of the nervous system",
      "malignant tumour of nervous system",
      "malignant tumour of the nervous system",
      "nervous system cancer",
      "nervous system neoplasms, malignant"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A primary or metastatic malignant neoplasm involving the nervous system."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 6733,
      "label": "cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050686",
          "DOID:0050687",
          "DOID:162",
          "ICD9:195.8",
          "ICD9:199",
          "ICD9:199.1",
          "ICDO:8000/3",
          "MEDGEN:14297",
          "NCIT:C9305",
          "ONCOTREE:MT",
          "SCTID:363346000",
          "UMLS:C0006826",
          "birnlex:406"
        ],
        "synonyms": [
          "CA",
          "cancer",
          "cell type cancer",
          "malignancy",
          "malignant growth",
          "malignant neoplasm",
          "malignant neoplasm (disease)",
          "malignant neoplastic disease",
          "malignant tumor",
          "malignant tumour",
          "neoplasm (disease), malignant",
          "neoplasm, malignant",
          "MT"
        ],
        "definition": "A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas."
      },
      "child_count": 33,
      "reference_id": "MONDO:0004992"
    },
    {
      "id": 20456,
      "label": "nervous system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        6799
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:45046",
          "NCIT:C3268",
          "UMLS:C0027766"
        ],
        "synonyms": [
          "neoplasm of nervous system",
          "neoplasm of the nervous system",
          "nervous system neoplasm (disease)",
          "nervous system neoplasms",
          "nervous system tumor",
          "nervous system tumour",
          "tumor of nervous system",
          "tumor of the nervous system",
          "tumour of nervous system",
          "tumour of the nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the nervous system."
      },
      "child_count": 14,
      "reference_id": "MONDO:0021248"
    }
  ],
  "children": [
    {
      "id": 3050,
      "label": "sensory system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060116"
        ],
        "synonyms": [
          "cancer of sensory system",
          "malignant neoplasm of sensory system",
          "malignant sensory system neoplasm",
          "sensory system cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the sensory system"
      },
      "child_count": 7,
      "reference_id": "MONDO:0000649"
    },
    {
      "id": 4753,
      "label": "central nervous system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7479,
        7694
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3620",
          "EFO:0000326",
          "GARD:0027614",
          "ICD9:239.7",
          "MEDGEN:87593",
          "MESH:D016543",
          "NANDO:2100007",
          "NCIT:C4627",
          "SCTID:126951006",
          "UMLS:C0348374"
        ],
        "synonyms": [
          "CNS neoplasm",
          "central nervous system tumor",
          "central nervous system tumour",
          "CNS cancer",
          "CNS malignant neoplasms",
          "CNS neoplasms, malignant",
          "cancer of CNS",
          "cancer of central nervous system",
          "cancer of the CNS",
          "cancer of the central nervous system",
          "central nervous system cancer",
          "central nervous system neoplasms, malignant",
          "central nervous system tumours",
          "malignant CNS neoplasm",
          "malignant CNS neoplasms",
          "malignant CNS tumor",
          "malignant CNS tumour",
          "malignant central nervous system neoplasm",
          "malignant central nervous system tumor",
          "malignant central nervous system tumour",
          "malignant neoplasm of CNS",
          "malignant neoplasm of central nervous system",
          "malignant neoplasm of the CNS",
          "malignant neoplasm of the central nervous system",
          "malignant tumor of CNS",
          "malignant tumor of central nervous system",
          "malignant tumor of the CNS",
          "malignant tumor of the central nervous system",
          "malignant tumour of CNS",
          "malignant tumour of central nervous system",
          "malignant tumour of the CNS",
          "malignant tumour of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the central nervous system"
      },
      "child_count": 40,
      "reference_id": "MONDO:0002714"
    },
    {
      "id": 4869,
      "label": "ectomesenchymoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6816,
        7479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4055",
          "GARD:0012279",
          "ICDO:8921/3",
          "MEDGEN:98123",
          "NCIT:C4716",
          "UMLS:C0431111"
        ],
        "synonyms": [
          "ectomesenchymoma",
          "malignant ectomesenchymoma",
          "rhabdomyosarcoma with ganglionic differentiation (morphologic abnormality)",
          "sarcoma with ganglionic or neuroectodermal differentiation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An aggressive malignant mesenchymal neoplasm of the nervous system or soft tissues. It is characterized by the presence of a sarcomatous component (most often rhabdomyosarcoma) and a ganglionic or a neuroectodermal component."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002855"
    },
    {
      "id": 7654,
      "label": "adrenal gland neuroblastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2990,
        5499,
        7479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5718",
          "EFO:1000075",
          "GARD:0024283",
          "MEDGEN:154328",
          "NCIT:C4827",
          "SCTID:281562007",
          "UMLS:C0559460"
        ],
        "synonyms": [
          "adrenal gland neuroblastoma",
          "adrenal neuroblastoma",
          "neuroblastoma of adrenal",
          "neuroblastoma of adrenal gland",
          "neuroblastoma of the adrenal",
          "neuroblastoma of the adrenal gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neuroblastoma arising from the adrenal gland."
      },
      "child_count": 3,
      "reference_id": "MONDO:0006076"
    },
    {
      "id": 19079,
      "label": "cutaneous neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4255,
        4707,
        5298,
        7479,
        17658,
        20691
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009266",
          "ICD10CM:C4A",
          "ICD9:209.36",
          "ICDO:8247/3",
          "MEDGEN:2843",
          "MESH:D015266",
          "NCIT:C9231",
          "NORD:1947",
          "ONCOTREE:MCC",
          "Orphanet:79140",
          "SCTID:253001006",
          "UMLS:C0007129",
          "icd11.foundation:680322043"
        ],
        "synonyms": [
          "MCC",
          "Merkel Cell Carcinoma",
          "Merkel cell cancer",
          "Merkel cell carcinoma",
          "Merkel cell tumor",
          "Merkel cell tumour",
          "carcinoma of Merkel cell",
          "cutaneous APUDoma",
          "cutaneous neuroendocrine carcinoma",
          "neuroendocrine carcinoma of skin",
          "neuroendocrine carcinoma of the skin",
          "neuroendocrine skin carcinoma",
          "trabecular cancer",
          "trabecular skin carcinoma",
          "Merkle tumors",
          "Merkle tumours",
          "carcinoma, Merkel cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Cutaneous neuroendocrine carcinoma is a primary cutaneous cancer arising from a subset of skin neuroendocrine cells (Merkel cells, giving the name Merkel cell carcinoma (MCC))."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019210"
    },
    {
      "id": 20329,
      "label": "peripheral nervous system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3627,
        7479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:171.9",
          "MEDGEN:155556",
          "NCIT:C4961",
          "SCTID:254986007",
          "UMLS:C0751428"
        ],
        "synonyms": [
          "cancer of peripheral nervous system",
          "malignant PNS neoplasm",
          "malignant PNS tumor",
          "malignant PNS tumour",
          "malignant neoplasm of PNS",
          "malignant neoplasm of peripheral nerve",
          "malignant neoplasm of peripheral nervous system",
          "malignant neoplasm of the PNS",
          "malignant neoplasm of the peripheral nerve",
          "malignant neoplasm of the peripheral nervous system",
          "malignant neoplasms, peripheral nerve",
          "malignant peripheral nerve neoplasm",
          "malignant peripheral nerve tumor",
          "malignant peripheral nerve tumour",
          "malignant peripheral nervous system neoplasm",
          "malignant peripheral nervous system tumor",
          "malignant peripheral nervous system tumour",
          "malignant tumor of PNS",
          "malignant tumor of peripheral nerve",
          "malignant tumor of peripheral nervous system",
          "malignant tumor of the PNS",
          "malignant tumor of the peripheral nerve",
          "malignant tumor of the peripheral nervous system",
          "malignant tumour of PNS",
          "malignant tumour of peripheral nerve",
          "malignant tumour of peripheral nervous system",
          "malignant tumour of the PNS",
          "malignant tumour of the peripheral nerve",
          "malignant tumour of the peripheral nervous system",
          "peripheral nervous system cancer",
          "peripheral nervous system neoplasms, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Malignant growth of cells in the peripheral nervous system (PNS)or Autonomic Nervous System (ANS), without specification as to location"
      },
      "child_count": 36,
      "reference_id": "MONDO:0021089"
    }
  ],
  "roots": [
    {
      "id": 6733,
      "label": "cancer"
    },
    {
      "id": 20456,
      "label": "nervous system neoplasm"
    }
  ]
}