{
  "id": 7481,
  "label": "neuroschistosomiasis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005874",
  "properties": {
    "xrefs": [
      "DOID:13722",
      "EFO:0007394",
      "GARD:0024249",
      "MEDGEN:155718",
      "MESH:D020818",
      "UMLS:C0752191",
      "icd11.foundation:446216876"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Schistosomiasis of the brain, spinal cord, or meninges caused by infections with trematodes of the genus schistosoma (primarily schistosoma japonicum; schistosoma mansoni; and schistosoma haematobium in humans). S. japonicum infections of the nervous system may cause an acute meningoencephalitis or a chronic encephalopathy. S. mansoni and S. haematobium nervous system infections are associated with acute transverse myelitis involving the lower portions of the spinal cord. (From Joynt, Clinical Neurology, 1998, Ch27, pp61-2)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16140,
      "label": "schistosomiasis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6448,
        23869
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1395",
          "EFO:1001475",
          "GARD:0009687",
          "ICD10CM:B65",
          "ICD9:120.8",
          "ICD9:120.9",
          "MEDGEN:48573",
          "MESH:D012552",
          "MedDRA:10039603",
          "NCIT:C35000",
          "Orphanet:1247",
          "SCTID:10087007",
          "UMLS:C0036323",
          "icd11.foundation:1194562592"
        ],
        "synonyms": [
          "Bilharzia",
          "bilharziasis",
          "schistosomiasis",
          "snail fever"
        ],
        "definition": "An infectious disease caused by parasitic trematodes of the genus Schistosoma that colonize human blood vessels and release eggs that can cause granulomatous reactions leading to acute (swimmer's itch or acute schistosomiasis syndrome) or chronic disease. Depending on where the eggs lodge, manifestations of chronic schistosomiasis can include diarrhea, abdominal pain, loss of appetite, anemia (intestines), hepatosplenism, periportal fibrosis with portal hypertension (liver), urogenital inflammation and scarring, hematuria and dysuria (genitourinary system). Other patients may be asymptomatic."
      },
      "child_count": 14,
      "reference_id": "MONDO:0015254"
    },
    {
      "id": 21534,
      "label": "central nervous system infectious disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001456",
          "GARD:0025438",
          "ICD9:349.89",
          "MEDGEN:1684837",
          "MESH:D002494",
          "NCIT:C27582",
          "SCTID:128117002",
          "UMLS:C4759823"
        ],
        "synonyms": [
          "central nervous system infectious disease",
          "central nervous system infectious disorder",
          "infectious disease of central nervous system",
          "central nervous system infection",
          "infections, central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An infectious process that affects the brain and/or spinal cord. Representative examples include encephalitis, poliomyelitis, arachnoiditis, and meningitis."
      },
      "child_count": 24,
      "reference_id": "MONDO:0024619"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16140,
      "label": "schistosomiasis"
    },
    {
      "id": 21534,
      "label": "central nervous system infectious disorder"
    }
  ]
}