{
  "id": 7558,
  "label": "spleen cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005966",
  "properties": {
    "xrefs": [
      "DOID:672",
      "EFO:0007491",
      "GARD:0024265",
      "ICD10CM:C26.1",
      "MEDGEN:102271",
      "MESH:D013160",
      "NCIT:C3539",
      "SCTID:127230005",
      "UMLS:C0153470",
      "icd11.foundation:347078862"
    ],
    "synonyms": [
      "spleen neoplasm",
      "splenic neoplasm",
      "cancer of spleen",
      "cancer of the spleen",
      "malignant neoplasm of spleen",
      "malignant neoplasm of the spleen",
      "malignant spleen neoplasm",
      "malignant splenic neoplasm",
      "malignant splenic tumor",
      "malignant splenic tumour",
      "malignant tumor of spleen",
      "malignant tumor of the spleen",
      "malignant tumour of the spleen",
      "spleen cancer",
      "splenic cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A malignant neoplasm involving the spleen"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 3023,
      "label": "lymphatic system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3028,
        7447
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060073"
        ],
        "synonyms": [
          "cancer of lymphatic part of lymphoid system",
          "lymphatic part of lymphoid system cancer",
          "malignant lymphatic part of lymphoid system neoplasm",
          "malignant neoplasm of lymphatic part of lymphoid system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the lymphatic part of lymphoid system"
      },
      "child_count": 8,
      "reference_id": "MONDO:0000612"
    },
    {
      "id": 4587,
      "label": "digestive system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6151,
        6733,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3119",
          "ICD10CM:C15-C26",
          "ICD9:239.0",
          "MEDGEN:148231",
          "NCIT:C4890",
          "UMLS:C0751075"
        ],
        "synonyms": [
          "GI tumor",
          "GI tumour",
          "cancer of digestive system",
          "digestive system cancer",
          "gastrointestinal system cancer",
          "malignant digestive system neoplasm",
          "malignant gastrointestinal neoplasm",
          "malignant gastrointestinal system neoplasm",
          "malignant neoplasm of digestive system"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm involving any part of the digestive system."
      },
      "child_count": 45,
      "reference_id": "MONDO:0002516"
    },
    {
      "id": 22946,
      "label": "spleen neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4438,
        4440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007683",
          "MEDGEN:21292",
          "NCIT:C3383",
          "UMLS:C0037999"
        ],
        "synonyms": [
          "neoplasm of spleen",
          "spleen tumor",
          "spleen tumour",
          "splenic neoplasm",
          "tumor of spleen",
          "tumour of spleen"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the spleen. Representative examples include hemangioma, lymphoma, splenic involvement by leukemia, and angiosarcoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0036696"
    }
  ],
  "children": [
    {
      "id": 4473,
      "label": "spleen angiosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7558,
        17394
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:265",
          "GARD:0023126",
          "ICD9:159.1",
          "MEDGEN:83426",
          "NCIT:C4564",
          "SCTID:187821001",
          "UMLS:C0346424"
        ],
        "synonyms": [
          "angiosarcoma (disease) of spleen",
          "angiosarcoma of spleen",
          "angiosarcoma of the spleen",
          "hemangiosarcoma of spleen",
          "hemangiosarcoma of the spleen",
          "spleen angiosarcoma (disease)",
          "splenic angiosarcoma",
          "splenic hemangiosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant vascular neoplasm arising from the spleen."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002376"
    },
    {
      "id": 5941,
      "label": "splenic manifestation of leukemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6789,
        7558
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:710",
          "GARD:0023828",
          "MEDGEN:234813",
          "NCIT:C7296",
          "UMLS:C1336065"
        ],
        "synonyms": [
          "leukaemia (disease) of spleen",
          "leukemia (disease) of spleen",
          "spleen leukaemia (disease)",
          "spleen leukemia (disease)",
          "splenic manifestation of leukemia",
          "splenic leukaemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A leukemia (disease) that involves the spleen."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004107"
    },
    {
      "id": 7779,
      "label": "gastric mucosa-associated lymphoid tissue lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7558,
        9011,
        18536,
        23066
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000274",
          "GARD:0024340",
          "MEDGEN:232547",
          "NCIT:C5266",
          "UMLS:C1333782"
        ],
        "synonyms": [
          "MALT lymphoma of stomach",
          "MALT lymphoma of the stomach",
          "MALToma of stomach",
          "MALToma of the stomach",
          "gastric MALT lymphoma",
          "gastric MALToma",
          "gastric mucosa-associated lymphoid tissue lymphoma",
          "primary MALT lymphoma of stomach",
          "primary MALT lymphoma of the stomach",
          "primary gastric B-cell MALT lymphoma",
          "primary gastric MALT lymphoma",
          "stomach MALT lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A low grade, indolent B-cell lymphoma, usually associated with Helicobacter pylori infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic (centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006226"
    },
    {
      "id": 7937,
      "label": "small intestinal mucosa-associated lymphoid tissue lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4030,
        7558,
        9011
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024407",
          "MEDGEN:233452",
          "NCIT:C5635",
          "UMLS:C1336004"
        ],
        "synonyms": [
          "MALT lymphoma of small bowel",
          "MALT lymphoma of small intestine",
          "MALT lymphoma of the small bowel",
          "MALT lymphoma of the small intestine",
          "MALToma of small bowel",
          "MALToma of small intestine",
          "MALToma of the small bowel",
          "MALToma of the small intestine",
          "mucosa-associated lymphoid tissue lymphoma of small bowel",
          "mucosa-associated lymphoid tissue lymphoma of small intestine",
          "mucosa-associated lymphoid tissue lymphoma of the small bowel",
          "mucosa-associated lymphoid tissue lymphoma of the small intestine",
          "small bowel MALT lymphoma",
          "small bowel MALToma",
          "small bowel mucosa-associated lymphoid tissue lymphoma",
          "small intestinal mucosa-associated lymphoid tissue lymphoma",
          "small intestine MALT lymphoma",
          "small intestine MALToma",
          "small intestine mucosa-associated lymphoid tissue lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A mucosa-associated lymphoid tissue lymphoma (MALT) that arises from the small intestine. The morphologic characteristics are similar to those seen in gastric MALT lymphomas, with the exception of the lymphoepithelial lesions that are less prominent in the small intestine."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006420"
    },
    {
      "id": 23468,
      "label": "tonsillar lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6479,
        7558,
        8421,
        9011,
        18718
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025917",
          "MEDGEN:234432",
          "NCIT:C5918",
          "UMLS:C1336765"
        ],
        "synonyms": [
          "Primary tonsillar lymphoma",
          "lymphoma of the tonsil",
          "lymphoma of tonsil",
          "tonsil lymphoma",
          "tonsillar lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A primary lymphoma that affects the tonsil and the bulk of the tumor is in this anatomic area. The majority of cases are B-cell non-Hodgkin lymphomas."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044884"
    }
  ],
  "roots": [
    {
      "id": 3023,
      "label": "lymphatic system cancer"
    },
    {
      "id": 4587,
      "label": "digestive system cancer"
    },
    {
      "id": 22946,
      "label": "spleen neoplasm"
    }
  ]
}