{
  "id": 7571,
  "label": "thoracic outlet syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0005979",
  "properties": {
    "xrefs": [
      "DOID:3103",
      "EFO:0007507",
      "MEDGEN:21158",
      "MESH:D013901",
      "MedDRA:10048627",
      "NCIT:C85188",
      "NORD:1766",
      "Orphanet:97330",
      "SCTID:128210009",
      "UMLS:C0039984",
      "icd11.foundation:909280105"
    ],
    "synonyms": [
      "TOS",
      "thoracic outlet compression syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A syndrome resulting from the compression of the blood vessels or nerves in the space between the clavicle and first rib (thoracic outlet). It is caused by car accident injuries or repetitive job or sport-related injuries. Signs and symptoms include pain in the shoulders and neck, numbness in the fingers, and weakening grip."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 7065,
      "label": "vascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:178",
          "EFO:0004264",
          "ICD10CM:I00-I99",
          "ICD10CM:I70-I79",
          "ICD9:442.9",
          "MEDGEN:22621",
          "MESH:D014652",
          "NANDO:2100294",
          "NCIT:C35117",
          "SCTID:27550009",
          "UMLS:C0042373"
        ],
        "synonyms": [
          "disease of vasculature",
          "disease or disorder of vasculature",
          "disorder of vasculature",
          "vascular disorder",
          "vasculature disease",
          "vasculature disease or disorder",
          "vasculopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A general term used to describe any disease affecting blood vessels]. It includes vascular abnormalities caused by degenerative, metabolic and inflammatory conditions, embolic diseases, coagulative disorders, and functional disorders such as posteri or reversible encephalopathy syndrome."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005385"
    }
  ],
  "children": [
    {
      "id": 16035,
      "label": "neurogenic thoracic outlet syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7571
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019749",
          "MEDGEN:155880",
          "Orphanet:100073",
          "SCTID:2040007",
          "UMLS:C0751549"
        ],
        "synonyms": [
          "NTOS",
          "neurogenic TOS",
          "neurogenic cervical rib syndrome",
          "neurogenic costoclavicular syndrome",
          "neurogenic thoracic outlet compression syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Neurogenic thoracic outlet syndrome (NTOS) is a form of thoracic outlet syndrome (TOS) that presents with pain, paresthesias and weakness in an upper extremity and is divided into true NTOS and disputed NTOS."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015061"
    },
    {
      "id": 18308,
      "label": "arterial thoracic outlet syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7571
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021535",
          "MEDGEN:365116",
          "Orphanet:357107",
          "SCTID:8051000119105",
          "UMLS:C1956395"
        ],
        "synonyms": [
          "ATOS",
          "arterial TOS",
          "arterial cervical rib syndrome",
          "arterial costoclavicular syndrome",
          "arterial hyperabduction syndrome",
          "arterial scalenus anticus syndrome",
          "arterial thoracic outlet compression syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Arterial thoracic outlet syndrome (ATOS) is a form of thoracic outlet syndrome (TOS) that presents as unilateral upper extremity ischemia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018164"
    },
    {
      "id": 18309,
      "label": "venous thoracic outlet syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7571
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021536",
          "MEDGEN:408326",
          "Orphanet:357131",
          "SCTID:25981000119102",
          "UMLS:C1956396"
        ],
        "synonyms": [
          "Paget-Schrotter disease",
          "VTOS",
          "Venous TOS",
          "Venous cervical rib syndrome",
          "Venous costoclavicular syndrome",
          "Venous hyperabduction syndrome",
          "Venous scalenus anticus syndrome",
          "Venous thoracic outlet compression syndrome",
          "effort subclavian vein thrombosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Venous thoracic outlet syndrome (VTOS) is a form of thoracic outlet syndrome (TOS) that manifests as unilateral (rarely bilateral) arm pain and cyanosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018165"
    }
  ],
  "roots": [
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 7065,
      "label": "vascular disorder"
    }
  ]
}