{
  "id": 7608,
  "label": "yaws",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006019",
  "properties": {
    "xrefs": [
      "DOID:10371",
      "GARD:0007913",
      "ICD10CM:A66",
      "ICD10WHO:A66",
      "ICD9:102",
      "ICD9:102.7",
      "ICD9:102.9",
      "MEDGEN:12186",
      "MESH:D015001",
      "NCIT:C41353",
      "NORD:1872",
      "SCTID:70647001",
      "UMLS:C0043388",
      "icd11.foundation:840525023"
    ],
    "synonyms": [
      "Bouba",
      "Treponema pallidum subsp. pertenue caused disease or disorder",
      "Treponema pallidum subsp. pertenue disease or disorder",
      "Treponema pallidum subsp. pertenue infectious disease",
      "frambesia",
      "frambesia tropica",
      "Treponema pertenue infection",
      "endemic treponematoses"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "An endemic, infectious, nonvenereal disease in humans that presents mainly in children younger than 15 years. The disease occurs primarily in warm, humid, tropical areas of Africa, Asia, South America, and Oceania, among poor rural populations where conditions of overcrowding and poor sanitation prevail. Infection with Treponema pertenue, a subspecies of Treponema pallidum, causes the disease."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 7568,
      "label": "syphilis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2837,
        8423
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4166",
          "EFO:0007504",
          "GARD:0027732",
          "ICD9:097.9",
          "MEDGEN:21447",
          "MESH:D013587",
          "MedDRA:10062120",
          "NCIT:C35055",
          "SCTID:76272004",
          "UMLS:C0039128",
          "icd11.foundation:455894495"
        ],
        "synonyms": [
          "Treponema pallidum caused disease or disorder",
          "Treponema pallidum disease or disorder",
          "Treponema pallidum infectious disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A contagious bacterial infection caused by the spirochete Treponema pallidum. It is a sexually transmitted disorder, although it can also be transmitted from the mother to the fetus in utero. Typically, it is initially manifested with a single sore which heals without treatment. If the infection is left untreated, the initial stage is followed by skin rash and mucous membrane lesions. A late stage follows, which is characterized by damage of the internal organs, including the nervous system."
      },
      "child_count": 20,
      "reference_id": "MONDO:0005976"
    }
  ],
  "children": [
    {
      "id": 3321,
      "label": "late yaws",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7608,
        8179
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10567",
          "GARD:0022872",
          "ICD10CM:A66.4",
          "ICD9:102.1",
          "ICD9:102.4",
          "MEDGEN:276026",
          "NCIT:C41354",
          "SCTID:186968004",
          "UMLS:C1517744"
        ],
        "synonyms": [
          "gummata and ulcers due to yaws",
          "gummatous frambeside",
          "nodular late yaws"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Late yaws is the tertiary, non-contagious stage of yaws, endemic tropical treponemal nonvenereal infection. Late yaws is characterized by destructive and deforming lesions of the skin, bones, and joints."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001066"
    },
    {
      "id": 3322,
      "label": "early yaws",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7608
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10568",
          "GARD:0022873",
          "ICD9:102.0",
          "ICD9:102.2",
          "ICD9:102.6",
          "MEDGEN:124440",
          "NCIT:C41352",
          "SCTID:23191004",
          "UMLS:C0275998"
        ],
        "synonyms": [
          "bone and joint lesions due to yaws",
          "initial lesions of yaws"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Early yaws includes primary and secondary stages of yaws, endemic tropical treponemal nonvenereal infection: development of initial lesion at inoculation site followed by widespread dissemination of treponemes and generalized secondary granulomatous lesions that may relapse repeatedly."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001067"
    },
    {
      "id": 23018,
      "label": "latent yaws",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7608
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025832",
          "ICD10CM:A66.8",
          "MEDGEN:509217",
          "SCTID:186973005",
          "UMLS:C0153240",
          "icd11.foundation:247169608"
        ],
        "synonyms": [
          "latent yaws"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0040925"
    },
    {
      "id": 23056,
      "label": "tertiary lesion of yaws",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7608
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025845",
          "MEDGEN:575866",
          "SCTID:88037009",
          "UMLS:C0343833"
        ],
        "synonyms": [
          "tertiary lesion of yaws",
          "tertiary stage of yaws",
          "tertiary yaws"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0042452"
    }
  ],
  "roots": [
    {
      "id": 7568,
      "label": "syphilis"
    }
  ]
}