{
  "id": 7619,
  "label": "diffuse intrinsic pontine glioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006033",
  "properties": {
    "xrefs": [
      "EFO:1000026",
      "GARD:0013075",
      "MEDGEN:458884",
      "MESH:D000080443",
      "NCIT:C94764",
      "ONCOTREE:DIPG",
      "Orphanet:497188",
      "UMLS:C2986658"
    ],
    "synonyms": [
      "DIPG",
      "diffuse midline glioma",
      "infiltrative brainstem glioma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A neuroglial tumor that arises from the middle portion of the brain stem. It usually affects children and has a poor prognosis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5734,
      "label": "childhood brain stem glioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4918,
        4921
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6383",
          "GARD:0009306",
          "MEDGEN:124481",
          "NCIT:C9042",
          "UMLS:C0278600"
        ],
        "synonyms": [
          "brain stem glioma",
          "brain stem glioma of childhood",
          "childhood brain stem glioma",
          "childhood brainstem glioma",
          "childhood glioma of brain stem",
          "childhood glioma of brainstem",
          "childhood glioma of the brain stem",
          "childhood glioma of the brainstem",
          "paediatric brain stem glioma",
          "paediatric brainstem glioma",
          "paediatric glioma of brain stem",
          "paediatric glioma of brainstem",
          "paediatric glioma of the brain stem",
          "paediatric glioma of the brainstem",
          "pediatric brain stem glioma",
          "pediatric brainstem glioma",
          "pediatric glioma of brain stem",
          "pediatric glioma of brainstem",
          "pediatric glioma of the brain stem",
          "pediatric glioma of the brainstem"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An abnormal growth of the cells that comprise the tissues of the brainstem. While the tumor may be histologically benign, it can produce great morbidity due to its location. It presents most commonly in the first two decades of life."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003869"
    }
  ],
  "children": [
    {
      "id": 29334,
      "label": "diffuse midline glioma, H3 K27-altered",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7619
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0028173",
          "MEDGEN:1811313",
          "NCIT:C185368",
          "UMLS:C5669877"
        ],
        "synonyms": [
          "DMG, H3 K27-altered"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A diffuse midline glioma characterized by H3 K27 alteration and usually either a histone H3 K27M mutation, an EGFR mutation, or aberrant overexpression of EZHIP. The prognosis is poor."
      },
      "child_count": 1,
      "reference_id": "MONDO:1060171"
    }
  ],
  "roots": [
    {
      "id": 5734,
      "label": "childhood brain stem glioma"
    }
  ]
}