{
  "id": 7635,
  "label": "pleomorphic breast carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006050",
  "properties": {
    "xrefs": [
      "EFO:1000047",
      "MEDGEN:307976",
      "NCIT:C5161",
      "UMLS:C1514169"
    ],
    "synonyms": [
      "anaplastic breast carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "A rare, aggressive, high grade invasive ductal carcinoma, not otherwise specified. It is characterized by the presence of pleomorphic and bizarre malignant cells that constitute more than 50 percent of the malignant cellular infiltrate."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6698,
      "label": "invasive ductal breast carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7234,
        7803
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3008",
          "EFO:0000186",
          "ICD9:174.8",
          "ICDO:8500/3",
          "ICDO:8521/3",
          "MEDGEN:730612",
          "NCIT:C4194",
          "ONCOTREE:IDC",
          "SCTID:408643008",
          "UMLS:C1412014"
        ],
        "synonyms": [
          "infiltrating ductal adenocarcinoma",
          "infiltrating ductal breast carcinoma",
          "infiltrating ductal carcinoma",
          "infiltrating ductal carcinoma of breast",
          "infiltrating ductal carcinoma of the breast",
          "invasive ductal adenocarcinoma",
          "invasive ductal breast carcinoma",
          "invasive ductal carcinoma",
          "invasive ductal carcinoma of breast",
          "invasive ductal carcinoma of the breast",
          "invasive ductal carcinoma, NST",
          "invasive ductal carcinoma, No specific type",
          "breast invasive ductal carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "The most common type of invasive breast carcinoma, accounting for approximately 70% of breast carcinomas. The gross appearance is usually typical with an irregular stellate outline. Microscopically, randomly arranged epithelial elements are seen. When large sheets of malignant cells are present, necrosis may be seen. With adequate tissue sampling, in situ carcinoma can be demonstrated in association with the infiltrating carcinoma. The in situ component is nearly always ductal but occasionally may be lobular or both."
      },
      "child_count": 20,
      "reference_id": "MONDO:0004953"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6698,
      "label": "invasive ductal breast carcinoma"
    }
  ]
}