{
  "id": 7650,
  "label": "adenofibroma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006071",
  "properties": {
    "xrefs": [
      "DOID:2683",
      "EFO:1000070",
      "ICDO:9013/0",
      "MEDGEN:1325",
      "MESH:D000232",
      "NCIT:C8984",
      "UMLS:C0001422"
    ],
    "synonyms": [
      "adenofibroma, benign",
      "adenofibroma, no ICD-O subtype",
      "adenofibroma, no ICD-O subtype (morphologic abnormality)",
      "benign mixed Muellerian tumor",
      "benign mixed Muellerian tumour",
      "female reproductive system adenofibroma"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A benign neoplasm characterized by the presence of connective tissue stroma and epithelial structures. It occurs in the ovary, fallopian tube, uterine corpus, and cervix. Cases of adenofibroma of the ovary with low grade malignant potential have also been reported."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 3029,
      "label": "benign female reproductive system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2882,
        20384
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060086",
          "MEDGEN:152872",
          "NCIT:C4934",
          "UMLS:C0744514"
        ],
        "synonyms": [
          "benign female reproductive system neoplasm",
          "benign female reproductive system tumor",
          "benign female reproductive system tumour",
          "benign gynecologic neoplasm",
          "benign gynecologic tumor",
          "benign gynecologic tumour",
          "female reproductive organ benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm that arises from the female reproductive system. Representative examples include uterine corpus leiomyoma, endocervical polyp, and benign ovarian germ cell tumor."
      },
      "child_count": 14,
      "reference_id": "MONDO:0000624"
    },
    {
      "id": 6889,
      "label": "fibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050871",
          "EFO:0002424",
          "ICD9:215.9",
          "ICDO:8810/0",
          "MEDGEN:42016",
          "MESH:D005350",
          "NCIT:C3041",
          "SCTID:424568000",
          "UMLS:C0016045"
        ],
        "synonyms": [
          "fibroma",
          "fibroma, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts."
      },
      "child_count": 11,
      "reference_id": "MONDO:0005167"
    }
  ],
  "children": [
    {
      "id": 4488,
      "label": "mucinous adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7650,
        21367,
        22952
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2700",
          "ICDO:9015/0",
          "MEDGEN:83158",
          "NCIT:C8978",
          "UMLS:C0334499"
        ],
        "synonyms": [
          "mucinous adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign adenofibroma characterized by the presence of epithelial cells which contain intracytoplasmic mucin and a fibrotic stroma. A representative example is the ovarian mucinous adenofibroma. Cases with epithelial atypia described in the ovary lacking stromal invasion are designated as borderline mucinous adenofibromas and have a low grade malignant potential."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002398"
    },
    {
      "id": 5380,
      "label": "uterine corpus adenofibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7650,
        20643
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5475",
          "MEDGEN:277849",
          "NCIT:C6337",
          "UMLS:C1336901"
        ],
        "synonyms": [
          "adenofibroma of body of uterus",
          "adenofibroma of corpus uteri",
          "adenofibroma of the body of uterus",
          "adenofibroma of the corpus uteri",
          "adenofibroma of the uterine body",
          "adenofibroma of the uterine corpus",
          "adenofibroma of uterine body",
          "body of uterus adenofibroma",
          "corpus uteri adenofibroma",
          "uterine body adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A usually polypoid, benign neoplasm that arises from the endometrial cavity. It is characterized by the presence of a mesenchymal core component and an epithelial component that forms a lining on the mesenchymal core."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003458"
    },
    {
      "id": 5382,
      "label": "clear cell adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7650
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5477",
          "ICDO:8313/0",
          "MEDGEN:90762",
          "NCIT:C8987",
          "UMLS:C0334317"
        ],
        "synonyms": [
          "clear cell adenofibroma",
          "clear cell adenofibroma (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign neoplasm characterized by the presence of glandular structures which contain clear cells and a fibrotic stroma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003460"
    },
    {
      "id": 5384,
      "label": "papillary adenofibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7650
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5479",
          "MEDGEN:237177",
          "NCIT:C8986",
          "UMLS:C1377850"
        ],
        "synonyms": [
          "papillary adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A biphasic polypoid neoplasm characterized by the presence of papillary projections that are lined by epithelial cells and fibrotic stroma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003462"
    },
    {
      "id": 5386,
      "label": "cystadenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7650
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5482",
          "MESH:D062625",
          "NCIT:C8985"
        ],
        "synonyms": [
          "cystadenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign or borderline neoplasm that arises from the ovaries and the fallopian tubes. It is characterized by the presence of cystic glandular structures and fibrous tissue."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003464"
    },
    {
      "id": 21610,
      "label": "serous adenofibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7650
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:9014/0",
          "MEDGEN:87253",
          "NCIT:C67090",
          "UMLS:C0334498"
        ],
        "synonyms": [
          "serous adenofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign adenofibroma characterized by the presence of serous secretory cells and minute cystic spaces filled with watery fluid. A representative example is the ovarian serous adenofibroma. Cases with epithelial atypia described in the ovary lacking stromal invasion are designated as borderline serous adenofibromas and have a low grade malignant potential."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024886"
    }
  ],
  "roots": [
    {
      "id": 3029,
      "label": "benign female reproductive system neoplasm"
    },
    {
      "id": 6889,
      "label": "fibroma"
    }
  ]
}