{
  "id": 7674,
  "label": "benign adrenal gland pheochromocytoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006103",
  "properties": {
    "xrefs": [
      "EFO:1000106",
      "GARD:0024293",
      "MEDGEN:317403",
      "NCIT:C48305",
      "UMLS:C1706920"
    ],
    "synonyms": [
      "adrenal gland pheochromocytoma, benign",
      "benign adrenal gland pheochromocytoma",
      "pheochromocytoma, benign"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A sporadic or familial pheochromocytoma that is confined to the adrenal gland and does not have any metastatic potential. The majority of cases are sporadic, and usually unilateral. Familial cases are usually bilateral."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6716,
      "label": "adrenal gland pheochromocytoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20313,
        20446
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050892",
          "EFO:0000239",
          "GARD:0024140",
          "ICDO:8700/0",
          "MEDGEN:1636437",
          "NANDO:2200078",
          "NCIT:C3326",
          "UMLS:C4551683"
        ],
        "synonyms": [
          "pheochromocytoma",
          "Intraadrenal paraganglioma",
          "PCC",
          "adrenal gland Chromaffinoma",
          "adrenal gland chromaffin paraganglioma",
          "adrenal gland paraganglioma",
          "adrenal gland pheochromocytoma",
          "adrenal medullary paraganglioma",
          "adrenal medullary pheochromocytoma",
          "adrenal pheochromocytoma",
          "chromaffin paraganglioma of the adrenal gland",
          "pheochromocytoma (adrenal)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neuroendocrine neoplasm of the sympathetic nervous system that secretes catecholamines. It arises from the chromaffin cells of the adrenal medulla. Clinical presentation includes headaches, palpitations, chest and abdominal pain, hypertension, fever, and tremor. Microscopically, a characteristic nesting (zellballen) growth pattern is usually seen. Other growth patterns including trabecular pattern may also be present."
      },
      "child_count": 6,
      "reference_id": "MONDO:0004974"
    },
    {
      "id": 20589,
      "label": "benign neoplasm of adrenal medulla",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20446,
        20630
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025321",
          "MEDGEN:151941",
          "NCIT:C4895",
          "SCTID:91968002",
          "UMLS:C0686512",
          "icd11.foundation:1573786673"
        ],
        "synonyms": [
          "adrenal medulla benign neoplasm",
          "benign adrenal medulla neoplasm",
          "benign adrenal medulla tumor",
          "benign adrenal medulla tumour",
          "benign neoplasm of the adrenal medulla",
          "benign tumor of adrenal medulla",
          "benign tumor of the adrenal medulla",
          "benign tumour of adrenal medulla",
          "benign tumour of the adrenal medulla"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the adrenal medulla."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021468"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6887,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8010/0",
          "ICDO:8011/0",
          "MEDGEN:90747",
          "NCIT:C4092",
          "UMLS:C0334232"
        ],
        "synonyms": [
          "benign epithelial neoplasm",
          "benign epithelial tumor",
          "benign epithelial tumour",
          "benign epithelioma",
          "benign neoplasm of epithelium",
          "benign neoplasm of the epithelium",
          "benign tumor of epithelium",
          "benign tumor of the epithelium",
          "benign tumour of epithelium",
          "benign tumour of the epithelium",
          "epithelial neoplasm, benign",
          "epithelioma, benign"
        ],
        "definition": "A neoplasm arising from the epithelial cells. It is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign epithelial neoplasms remain confined to the original site of growth and only rarely metastasize to other anatomic sites."
      },
      "child_count": 50,
      "reference_id": "MONDO:0036976"
    },
    {
      "id": 23665,
      "label": "benign neoplasm of peripheral nervous system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3033,
        3627
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080320",
          "MEDGEN:199653",
          "UMLS:C0751427"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 16,
      "reference_id": "MONDO:0056804"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6716,
      "label": "adrenal gland pheochromocytoma"
    },
    {
      "id": 20589,
      "label": "benign neoplasm of adrenal medulla"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm"
    },
    {
      "id": 23665,
      "label": "benign neoplasm of peripheral nervous system"
    }
  ]
}