{
  "id": 7681,
  "label": "bladder flat intraepithelial lesion",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006111",
  "properties": {
    "xrefs": [
      "DOID:5429",
      "EFO:1000126",
      "MEDGEN:231947",
      "NCIT:C37266",
      "UMLS:C1332559"
    ],
    "synonyms": [
      "bladder flat intraepithelial lesion",
      "flat intraepithelial lesion of the bladder",
      "flat intraepithelial lesion of the urinary bladder",
      "urinary bladder flat intraepithelial lesion"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A non-papillary neoplasm of the urinary bladder, whose classification categories include low-grade intraurothelial neoplasia and urothelial carcinoma in situ."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6728,
      "label": "urinary bladder neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7612,
        20307
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000294",
          "ICD9:239.4",
          "MEDGEN:594",
          "NCIT:C2901",
          "SCTID:126885006",
          "UMLS:C0005695"
        ],
        "synonyms": [
          "bladder neoplasm",
          "bladder tumor",
          "bladder tumors",
          "bladder tumour",
          "bladder tumours",
          "neoplasm of bladder",
          "neoplasm of the bladder",
          "neoplasm of the urinary bladder",
          "neoplasm of urinary bladder",
          "tumor of bladder",
          "tumor of the bladder",
          "tumor of the urinary bladder",
          "tumor of urinary bladder",
          "tumour of bladder",
          "tumour of the bladder",
          "tumour of the urinary bladder",
          "tumour of urinary bladder",
          "urinary bladder neoplasm",
          "urinary bladder neoplasm (disease)",
          "urinary bladder neoplasms",
          "urinary bladder tumor",
          "urinary bladder tumors",
          "urinary bladder tumour",
          "urinary bladder tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A benign or malignant, primary or metastatic neoplasm of the bladder. - 2003"
      },
      "child_count": 12,
      "reference_id": "MONDO:0004987"
    }
  ],
  "children": [
    {
      "id": 6483,
      "label": "bladder carcinoma in situ",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5789,
        6433,
        7681
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9053",
          "GARD:0024091",
          "ICD10CM:D09.0",
          "ICD9:233.7",
          "MEDGEN:57584",
          "NCIT:C3644",
          "SCTID:92546004",
          "UMLS:C0154091"
        ],
        "synonyms": [
          "cancer in situ of urinary bladder",
          "bladder flat CIS",
          "bladder flat carcinoma in situ",
          "carcinoma in situ of bladder",
          "carcinoma in situ of the urinary bladder",
          "carcinoma in situ of urinary bladder",
          "flat CIS of the bladder",
          "flat CIS of the urinary bladder",
          "flat carcinoma in situ of the bladder",
          "flat carcinoma in situ of the urinary bladder",
          "high grade bladder Intraurothelial neoplasia",
          "stage 0 urinary bladder carcinoma",
          "stage 0is bladder cancer",
          "stage 0is bladder carcinoma",
          "stage 0is bladder urothelial cancer",
          "stage 0is bladder urothelial carcinoma",
          "stage 0is bladder urothelial carcinoma aJCC v6",
          "stage 0is bladder urothelial carcinoma aJCC v6 and v7",
          "stage 0is bladder urothelial carcinoma aJCC v7",
          "stage 0is carcinoma of bladder",
          "stage 0is carcinoma of the bladder",
          "stage 0is carcinoma of the urinary bladder",
          "stage 0is carcinoma of urinary bladder",
          "stage 0is urinary bladder carcinoma",
          "urinary bladder carcinoma in situ",
          "urinary bladder flat CIS",
          "urinary bladder flat carcinoma in situ",
          "urinary bladder in situ carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Also known as carcinoma in situ of the urinary bladder or high grade intraurothelial neoplasia, this is a flat lesion of the transitional cell epithelium characterized by severe cytologic atypia. This lesion is confined to the urothelium, and is a precursor of invasive transitional cell carcinoma of the bladder. Stage 0is includes: Tis, N0, M0. Tis: Carcinoma in situ: \"flat tumor\". N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0004703"
    }
  ],
  "roots": [
    {
      "id": 6728,
      "label": "urinary bladder neoplasm"
    }
  ]
}