{
  "id": 7685,
  "label": "breast diffuse large B-cell lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006117",
  "properties": {
    "xrefs": [
      "EFO:1000144",
      "GARD:0024299",
      "MEDGEN:267764",
      "NCIT:C40375",
      "UMLS:C1511306"
    ],
    "synonyms": [
      "breast DLBCL",
      "breast diffuse large B-cell lymphoma",
      "diffuse large B-cell lymphoma of breast"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A diffuse large B-cell lymphoma that arises from the breast. It is the most common type of primary breast lymphoma."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3028,
      "label": "immune system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        6778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060083"
        ],
        "synonyms": [
          "cancer of immune system",
          "immune system cancer",
          "malignant immune system neoplasm",
          "malignant neoplasm of immune system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the immune system"
      },
      "child_count": 50,
      "reference_id": "MONDO:0000621"
    },
    {
      "id": 3053,
      "label": "integumentary system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4198,
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060122"
        ],
        "synonyms": [
          "cancer of integumental system",
          "integumental system cancer",
          "malignant integumental system neoplasm",
          "malignant neoplasm of integumental system"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the integumental system"
      },
      "child_count": 14,
      "reference_id": "MONDO:0000653"
    },
    {
      "id": 5548,
      "label": "breast lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        8659
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5826",
          "GARD:0023608",
          "MEDGEN:309939",
          "NCIT:C4671",
          "SCTID:278052009",
          "UMLS:C1704251"
        ],
        "synonyms": [
          "breast lymphoma",
          "lymphoma of breast",
          "lymphoma of the breast",
          "primary breast lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that arises from the breast. There is no history of extramammary breast lymphoma and ipsilateral axillary lymph node involvement does not exclude the diagnosis of primary breast lymphoma. Most patients present with a painless breast lump. The vast majority of cases are B-cell non-Hodgkin lymphomas. Diffuse large B-cell lymphoma, follicular lymphoma, and extranodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue are the most common types of primary non-Hodgkin lymphoma of the breast. Primary Hodgkin lymphoma of the breast is rare."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003661"
    },
    {
      "id": 18833,
      "label": "diffuse large B-cell lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6694,
        17875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050745",
          "EFO:0000403",
          "GARD:0003178",
          "ICD10CM:C83.3",
          "ICD9:200.7",
          "ICDO:9680/3",
          "MEDGEN:86954",
          "MESH:D016403",
          "MedDRA:10012818",
          "NCIT:C8851",
          "Orphanet:544",
          "UMLS:C0079744",
          "icd11.foundation:1946973604"
        ],
        "synonyms": [
          "DLBCL",
          "diffuse large B-cell lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL) in adults characterized by a median age of presentation in the sixth decade of life (but also rarely occurring in adolescents and children) with the initial presentation being single or multiple rapidly growing masses (that may or may not be painful) in nodal or extranodal sites (such as thyroid, skin, breast, gastrointestinal tract, testes, bone, or brain) and that can be accompanied by symptoms of fever, night sweats and weight loss. DLBCL has an aggressive disease course, with the elderly having a poorer prognosis than younger patients, and with relapses being common."
      },
      "child_count": 60,
      "reference_id": "MONDO:0018905"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3028,
      "label": "immune system cancer"
    },
    {
      "id": 3053,
      "label": "integumentary system cancer"
    },
    {
      "id": 5548,
      "label": "breast lymphoma"
    },
    {
      "id": 18833,
      "label": "diffuse large B-cell lymphoma"
    }
  ]
}