{
  "id": 7693,
  "label": "central nervous system anaplastic large cell lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006128",
  "properties": {
    "xrefs": [
      "EFO:1000156",
      "GARD:0024302",
      "MEDGEN:235493",
      "NCIT:C5322",
      "UMLS:C1335476"
    ],
    "synonyms": [
      "anaplastic CNS large cell lymphoma",
      "anaplastic central nervous system large cell lymphoma",
      "anaplastic large cell lymphoma of CNS",
      "anaplastic large cell lymphoma of central nervous system",
      "anaplastic large cell lymphoma of the CNS",
      "anaplastic large cell lymphoma of the central nervous system",
      "central nervous system anaplastic large cell lymphoma",
      "primary CNS anaplastic large cell lymphoma",
      "primary central nervous system anaplastic large cell lymphoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "An anaplastic large cell lymphoma that affects the brain, meninges, or spinal cord."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 19798,
      "label": "anaplastic large cell lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2906
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050744",
          "EFO:0003032",
          "GARD:0003112",
          "HGNC:427",
          "ICD9:200.6",
          "ICD9:200.60",
          "ICDO:9714/3",
          "MEDGEN:61533",
          "MESH:D017728",
          "NANDO:2200021",
          "NCIT:C3720",
          "ONCOTREE:ALCL",
          "Orphanet:98841",
          "SCTID:277637000",
          "UMLS:C0206180"
        ],
        "synonyms": [
          "ALCL",
          "CD30 Positive anaplastic large cell lymphoma",
          "CD30 positive anaplastic large cell lymphoma",
          "Ki-1 lymphoma",
          "Ki-1 positive anaplastic large cell lymphoma",
          "Ki-1+ ALCL",
          "Ki-1+ anaplastic large cell lymphoma",
          "anaplastic large cell lymphoma",
          "primary systemic ALCL",
          "sACL"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Anaplastic large cell lymphoma (ALCL) is a rare and aggressive peripheral T-cell non-Hodgkin lymphoma, belonging to the group of CD30-positive lymphoproliferative disorders, which affects lymph nodes and extranodal sites. It is comprised of two sub-types, based on the expression of a protein called anaplastic lymphoma kinase (ALK): ALK positive and ALK negative ALCL."
      },
      "child_count": 5,
      "reference_id": "MONDO:0020325"
    },
    {
      "id": 20048,
      "label": "anaplastic cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:231373",
          "NCIT:C36025",
          "UMLS:C1332287"
        ],
        "synonyms": [
          "anaplastic malignant neoplasm"
        ]
      },
      "child_count": 8,
      "reference_id": "MONDO:0020633"
    },
    {
      "id": 23470,
      "label": "central nervous system non-hodgkin lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4634,
        16516
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025918",
          "MEDGEN:745669",
          "NCIT:C114779",
          "SCTID:448254007",
          "UMLS:C2213246"
        ],
        "synonyms": [
          "Central nervous system non-Hodgkin lymphoma",
          "Primary Central nervous system non-Hodgkin lymphoma",
          "central nervous system non-Hodgkin lymphoma",
          "non-Hodgkin lymphoma of central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A non-Hodgkin lymphoma that arises from the central nervous system."
      },
      "child_count": 4,
      "reference_id": "MONDO:0044887"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 19798,
      "label": "anaplastic large cell lymphoma"
    },
    {
      "id": 20048,
      "label": "anaplastic cancer"
    },
    {
      "id": 23470,
      "label": "central nervous system non-hodgkin lymphoma"
    }
  ]
}