{
  "id": 7701,
  "label": "cervical large cell neuroendocrine carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006138",
  "properties": {
    "xrefs": [
      "DOID:6659",
      "EFO:1000167",
      "GARD:0024306",
      "MEDGEN:275711",
      "NCIT:C40214",
      "ONCOTREE:CENE",
      "UMLS:C1516417"
    ],
    "synonyms": [
      "cervical large cell neuroendocrine carcinoma",
      "cervical neuroendocrine tumor",
      "cervical neuroendocrine tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A rare, aggressive neuroendocrine carcinoma that arises from the cervix and is characterized by the presence of malignant cells with abundant cytoplasm, large nuclei, and prominent nucleoli."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6787,
      "label": "large cell neuroendocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255,
        6943
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050872",
          "EFO:0000563",
          "GARD:0024145",
          "ICDO:8013/3",
          "MEDGEN:220402",
          "NCIT:C6875",
          "ONCOTREE:LUNE",
          "UMLS:C1265996",
          "icd11.foundation:1278312485"
        ],
        "synonyms": [
          "LCNEC",
          "large cell NEC",
          "large cell neuroendocrine carcinoma",
          "large-cell neuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005057"
    },
    {
      "id": 6855,
      "label": "cervical carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4978,
        6929
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2893",
          "EFO:0001061",
          "MEDGEN:86222",
          "NCIT:C9039",
          "SCTID:285432005",
          "UMLS:C0302592",
          "icd11.foundation:1743710977"
        ],
        "synonyms": [
          "cancer of cervix",
          "cancer of the cervix",
          "cancer of the uterine cervix",
          "cancer of uterine cervix",
          "cervical cancer",
          "cervical cancer, NOS",
          "cervix cancer",
          "uterine cervix cancer",
          "carcinoma of cervix",
          "carcinoma of cervix uteri",
          "carcinoma of the cervix",
          "carcinoma of the cervix uteri",
          "carcinoma of the uterine cervix",
          "carcinoma of uterine cervix",
          "cervical carcinoma",
          "cervix carcinoma",
          "cervix uteri carcinoma",
          "uterine cervix carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma."
      },
      "child_count": 18,
      "reference_id": "MONDO:0005131"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6787,
      "label": "large cell neuroendocrine carcinoma"
    },
    {
      "id": 6855,
      "label": "cervical carcinoma"
    }
  ]
}