{
  "id": 7739,
  "label": "digestive system mixed adenoneuroendocrine carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006182",
  "properties": {
    "xrefs": [
      "EFO:1000219",
      "ICDO:8244/3",
      "MEDGEN:459355",
      "NCIT:C95406",
      "UMLS:C2987129"
    ],
    "synonyms": [
      "MANEC",
      "digestive system Mixed Adenoneuroendocrine cancer",
      "digestive system mixed adenoneuroendocrine carcinoma",
      "gastrointestinal MANEC",
      "gastrointestinal mixed Adenoneuroendocrine carcinoma",
      "mixed Adenoneuroendocrine carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A carcinoma that arises from the digestive system and is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component. At least 30% of either component should be present for the diagnosis to be made."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 7738,
      "label": "digestive system carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4587,
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050922",
          "EFO:1000218",
          "HP:0002672",
          "MEDGEN:57467",
          "NCIT:C96963",
          "UMLS:C0151544"
        ],
        "synonyms": [
          "carcinoma of digestive system",
          "carcinoma of the gastrointestinal system",
          "digestive system carcinoma",
          "gastrointestinal carcinoma",
          "gastrointestinal carcinoma (disease)",
          "gastrointestinal system carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant neoplasm that arises from the epithelium of any part of the digestive system. Representative examples include colorectal carcinoma, esophageal carcinoma, and pancreatic carcinoma."
      },
      "child_count": 32,
      "reference_id": "MONDO:0006181"
    }
  ],
  "children": [
    {
      "id": 23412,
      "label": "pancreatic carcinoma with mixed differentiation",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6912,
        7739
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022057",
          "MEDGEN:353935",
          "NCIT:C45843",
          "Orphanet:506112",
          "UMLS:C1709050"
        ],
        "synonyms": [
          "MiNEN of pancreas",
          "mixed exocrine-endocrine carcinoma of the pancreas",
          "pancreatic MiNEN",
          "pancreatic carcinoma with mixed differentiation",
          "pancreatic mixed neuroendocrine-nonneuroendocrine neoplasm",
          "mixed neuroendocrine-nonneuroendocrine neoplasm of pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare carcinoma with a poor prognosis, characterized by the presence of a mixture of exocrine and neuroendocrine malignant epithelial cells in both the pancreas and metastatic sites. Symptoms include jaundice, abdominal pain, and weight loss."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044727"
    }
  ],
  "roots": [
    {
      "id": 7738,
      "label": "digestive system carcinoma"
    }
  ]
}