{
  "id": 7745,
  "label": "eccrine porocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006189",
  "properties": {
    "xrefs": [
      "DOID:7566",
      "EFO:1000229",
      "GARD:0007431",
      "ICDO:8409/3",
      "MEDGEN:266098",
      "MESH:D057090",
      "NCIT:C5560",
      "ONCOTREE:POCA",
      "SCTID:254708001",
      "UMLS:C1266065"
    ],
    "synonyms": [
      "eccrine porocarcinoma",
      "epidermotropic eccrine carcinoma",
      "malignant eccrine poroma",
      "porocarcinoma",
      "eccrine porocarcinoma of skin",
      "porocarcinoma/spiroadenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A carcinoma with eccrine differentiation arising from the sweat glands. It may arise de novo or as a malignant transformation of a pre-existing poroma. It usually grows in the legs, buttocks, feet, and trunk and usually presents as an ulcerative plaque. It is characterized by the presence of intraepidermal and dermal nests of malignant epithelial cells. It may recur after excision and metastasize to the lymph nodes and less frequently to distal anatomic sites."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 21295,
      "label": "eccrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7162,
        7178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4920",
          "ICDO:8413/3",
          "MEDGEN:690083",
          "NCIT:C27255",
          "SCTID:400173004",
          "UMLS:C1266066"
        ],
        "synonyms": [
          "carcinoma of eccrine sweat gland",
          "carcinoma, eccrine gland, malignant",
          "eccrine adenocarcinoma",
          "eccrine adenocarcinoma (morphologic abnormality)",
          "eccrine carcinoma",
          "eccrine carcinoma of skin",
          "eccrine sweat gland adenocarcinoma",
          "eccrine sweat gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An adenocarcinoma with eccrine differentiation arising from the sweat glands. It includes the following subtypes: ductal eccrine adenocarcinoma, papillary eccrine carcinoma, and eccrine porocarcinoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0024240"
    }
  ],
  "children": [
    {
      "id": 6100,
      "label": "vulvar eccrine porocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5726,
        7745
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7565",
          "GARD:0023910",
          "MEDGEN:275616",
          "NCIT:C40306",
          "UMLS:C1520081"
        ],
        "synonyms": [
          "eccrine porocarcinoma of mammalian vulva",
          "mammalian vulva eccrine porocarcinoma",
          "vulvar eccrine porocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An eccrine porocarcinoma that arises from the sweat glands in the vulva."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004281"
    }
  ],
  "roots": [
    {
      "id": 21295,
      "label": "eccrine carcinoma"
    }
  ]
}