{
  "id": 7755,
  "label": "epithelioid cell uveal melanoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006200",
  "properties": {
    "xrefs": [
      "DOID:7040",
      "EFO:1000244",
      "GARD:0024325",
      "MEDGEN:234223",
      "NCIT:C35780",
      "UMLS:C1333422"
    ],
    "synonyms": [
      "epithelioid cell melanoma of uvea",
      "epithelioid cell uveal melanoma",
      "uvea epithelioid cell melanoma",
      "uveal epithelioid cell melanoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "A uveal melanoma characterized by the presence of malignant large epithelioid melanocytes."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4977,
      "label": "epithelioid cell melanoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6832
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4360",
          "ICDO:8771/3",
          "MEDGEN:137763",
          "NCIT:C4236",
          "UMLS:C0334443"
        ],
        "synonyms": [
          "epithelioid cell malignant melanoma",
          "epithelioid cell melanoma",
          "epithelioid cell melanoma (morphologic abnormality)",
          "epithelioid melanoma"
        ],
        "definition": "A melanoma characterized by the presence of malignant large epithelioid melanocytes."
      },
      "child_count": 1,
      "reference_id": "MONDO:0002973"
    },
    {
      "id": 7983,
      "label": "uveal melanoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4710,
        7858
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6039",
          "EFO:1000616",
          "GARD:0008621",
          "MEDGEN:65077",
          "MESH:C536494",
          "MedDRA:10061252",
          "NCIT:C7712",
          "OMIM:155720",
          "ONCOTREE:UM",
          "Orphanet:39044",
          "UMLS:C0220633"
        ],
        "synonyms": [
          "intraocular melanoma",
          "melanoma (disease) of uvea",
          "melanoma of the uvea",
          "melanoma of uvea",
          "melanoma, uveal, malignant",
          "uvea melanoma",
          "uvea melanoma (disease)",
          "uveal melanoma",
          "iris melanoma",
          "choroidal melanoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A melanoma derived from melanocytes of the uveal tract. It is the most common primary intraocular tumor in the United States and Western Europe. Similar to melanoma of the skin, it is rare in Africa and Asia. Diagnostic procedures include ophthalmoscopic exam, fluorescein angiography and ultrasound. Treatment includes: surgical excision of the eye, iridocyclectomy and tumor resection. Recent treatments also include radiotherapy or photo coagulation. Classification of uveal melanomas recognizes four cell types within these tumors: epithelioid, intermediate, mixed cell, and spindle cell types. The spindle cell type uveal melanomas are further sub-classified as spindle cell type A and spindle cell type B."
      },
      "child_count": 16,
      "reference_id": "MONDO:0006486"
    }
  ],
  "children": [
    {
      "id": 5920,
      "label": "choroid epithelioid cell melanoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5741,
        7755
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7041",
          "GARD:0023810",
          "MEDGEN:232360",
          "NCIT:C6102",
          "UMLS:C1333024"
        ],
        "synonyms": [
          "choroid epithelioid cell melanoma",
          "choroidal epithelioid cell melanoma",
          "epithelioid cell melanoma of choroid",
          "epithelioid cell melanoma of optic choroid",
          "epithelioid cell melanoma of the choroid",
          "optic choroid epithelioid cell melanoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A epithelioid cell melanoma that involves the optic choroid."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004085"
    },
    {
      "id": 5921,
      "label": "ciliary body epithelioid cell melanoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5774,
        7755
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7042",
          "GARD:0023811",
          "MEDGEN:272484",
          "NCIT:C6119",
          "UMLS:C1333050"
        ],
        "synonyms": [
          "ciliary body epithelioid cell melanoma",
          "epithelioid cell melanoma of ciliary body",
          "epithelioid cell melanoma of the ciliary body"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A epithelioid cell melanoma that involves the ciliary body."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004086"
    }
  ],
  "roots": [
    {
      "id": 4977,
      "label": "epithelioid cell melanoma"
    },
    {
      "id": 7983,
      "label": "uveal melanoma"
    }
  ]
}