{
  "id": 7762,
  "label": "fibroblastic neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006209",
  "properties": {
    "xrefs": [
      "EFO:1000255",
      "MEDGEN:60198",
      "NCIT:C7075",
      "UMLS:C0206643"
    ],
    "synonyms": [
      "fibroblastic neoplasm",
      "fibroblastic tumor",
      "fibroblastic tumour",
      "fibrocytic neoplasm",
      "fibrocytic tumor",
      "fibrocytic tumour",
      "fibrogenic neoplasm",
      "fibrogenicTumor",
      "fibrous neoplasm",
      "fibrous tumor",
      "fibrous tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A benign, intermediate, or malignant mesenchymal neoplasm characterized by the presence of neoplastic fibroblasts."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 4667,
      "label": "mesenchymal cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3350",
          "MEDGEN:277359",
          "NCIT:C7059",
          "UMLS:C1334699"
        ],
        "synonyms": [
          "benign miscellaneous mesenchymal tumour",
          "mesenchymal cell neoplasm",
          "mesenchymal cell tumor",
          "mesenchymal cell tumour",
          "mesenchymal neoplasm",
          "mesenchymal tumor",
          "mesenchymal tumour"
        ],
        "definition": "A benign, intermediate, or malignant neoplasm that arises from the mesenchyma-derived cells of the soft tissue or bone. Representative examples include lipoma, leiomyoma, leiomyosarcoma and osteosarcoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002616"
    },
    {
      "id": 20678,
      "label": "connective tissue neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5762,
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:239.2",
          "MEDGEN:45035",
          "MESH:D009372",
          "SCTID:126598008",
          "UMLS:C0027656"
        ],
        "synonyms": [
          "connective tissue neoplasm",
          "connective tissue neoplasm (disease)",
          "connective tissue tumor",
          "connective tissue tumour",
          "neoplasm of connective tissue",
          "neoplasm of connective tissues",
          "tumor of connective tissue",
          "tumour of connective tissue",
          "connective tissue neoplasms",
          "neoplasm, connective tissue"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Neoplasms composed of connective tissue, including elastic, mucous, reticular, osseous, and cartilaginous tissue. The concept does not refer to neoplasms located in connective tissue."
      },
      "child_count": 26,
      "reference_id": "MONDO:0021581"
    }
  ],
  "children": [
    {
      "id": 6009,
      "label": "nodular fasciitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6588,
        7762,
        7941,
        19144
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7327",
          "GARD:0021959",
          "ICD10CM:M72.4",
          "ICD9:728.79",
          "MEDGEN:96076",
          "NCIT:C3827",
          "Orphanet:477742",
          "SCTID:400138001",
          "UMLS:C0410005",
          "icd11.foundation:789101380"
        ],
        "synonyms": [
          "nodular fasciitis",
          "pseudosarcomatous fasciitis",
          "pseudosarcomatous fibromatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A self-limiting, rapidly growing, non-encapsulated benign neoplasm that arises from the soft tissues. It is characterized by the presence of plump spindle-shaped fibroblasts, multinucleated osteoclast-like giant cells, chronic inflammatory infiltrate, red blood cell extravasation, and high mitotic activity."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004187"
    },
    {
      "id": 6765,
      "label": "fibromatosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000497",
          "MEDGEN:8836",
          "NCIT:C3042",
          "SCTID:723976005",
          "UMLS:C0016048"
        ],
        "synonyms": [
          "fibromatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A poorly circumscribed neoplasm arising from the soft tissues. It is characterized by the presence of spindle-shaped fibroblasts and an infiltrative growth pattern."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005031"
    },
    {
      "id": 6886,
      "label": "fibrosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7762,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3355",
          "EFO:0002087",
          "GARD:0002327",
          "HP:0100244",
          "ICD9:171.9",
          "ICDO:8810/3",
          "MEDGEN:5178",
          "MESH:D005354",
          "MedDRA:10016632",
          "NANDO:2200060",
          "NCIT:C3043",
          "ONCOTREE:FIBS",
          "Orphanet:2030",
          "SCTID:443250000",
          "UMLS:C0016057"
        ],
        "synonyms": [
          "fibrocytic tumor",
          "fibrocytic tumour",
          "fibrosarcoma",
          "fibrosarcoma (disease)",
          "fibrosarcoma (excluding infantile fibrosarcoma)",
          "fibrosarcoma - not infantile",
          "fibrosarcoma, malignant",
          "malignant fibromatous neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A malignant mesenchymal fibroblastic neoplasm affecting the soft tissue and bone."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005164"
    },
    {
      "id": 6889,
      "label": "fibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050871",
          "EFO:0002424",
          "ICD9:215.9",
          "ICDO:8810/0",
          "MEDGEN:42016",
          "MESH:D005350",
          "NCIT:C3041",
          "SCTID:424568000",
          "UMLS:C0016045"
        ],
        "synonyms": [
          "fibroma",
          "fibroma, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts."
      },
      "child_count": 11,
      "reference_id": "MONDO:0005167"
    },
    {
      "id": 16812,
      "label": "solitary fibrous tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015014",
          "ICD9:238.1",
          "ICDO:8815/0",
          "ICDO:8815/1",
          "ICDO:9051/0",
          "MEDGEN:224764",
          "MESH:D054364",
          "MedDRA:10018825",
          "NCIT:C7634",
          "ONCOTREE:SFT",
          "Orphanet:2126",
          "UMLS:C1266119"
        ],
        "synonyms": [
          "SFT",
          "localised fibrous mesothelioma",
          "localised fibrous tumour",
          "localized fibrous mesothelioma",
          "localized fibrous tumor",
          "solitary fibrous tumor",
          "submesothelial fibroma",
          "hemangiopericytoma",
          "solitary fibrous tumor/hemangiopericytoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Solitary fibrous tumor (SFT) represents a diverse group of ubiquitous rare spindle cell neoplasms that may be benign or malignant and that most frequently arises from the pleura and peritoneum and rarely from other sites such as head and neck, liver and skeletal muscle. SFT may be clinically asymptomatic or may present with enlarging mass, compressive effects depending on the site involved and rarely with paraneoplastic manifestations (osteoarthropathy or hypoglycemia)."
      },
      "child_count": 5,
      "reference_id": "MONDO:0016238"
    },
    {
      "id": 16951,
      "label": "elastofibroma dorsi",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020580",
          "ICDO:8820/0",
          "MEDGEN:87247",
          "NCIT:C4245",
          "Orphanet:228243",
          "UMLS:C0334460"
        ],
        "synonyms": [
          "Elastofibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign, slow-growing tumor arising from the soft tissues usually in the mid-thoracic region of the elderly. It is characterized by the presence of paucicellular collagenous tissue, adipocytes and a predominance of large coarse elastic fibers arranged in globules."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016440"
    },
    {
      "id": 23002,
      "label": "myofibroblastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8825/0",
          "MEDGEN:66894",
          "NCIT:C49012",
          "UMLS:C0242404"
        ],
        "synonyms": [
          "myofibroblastoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign, well circumscribed soft tissue neoplasm characterized by the presence of spindle shaped myofibroblasts and mast cells in a collagenous stroma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0040675"
    }
  ],
  "roots": [
    {
      "id": 4667,
      "label": "mesenchymal cell neoplasm"
    },
    {
      "id": 20678,
      "label": "connective tissue neoplasm"
    }
  ]
}