{
  "id": 7772,
  "label": "gallbladder small cell neuroendocrine carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006219",
  "properties": {
    "xrefs": [
      "DOID:7133",
      "EFO:1000266",
      "GARD:0024335",
      "MEDGEN:232229",
      "NCIT:C6763",
      "UMLS:C1333759"
    ],
    "synonyms": [
      "Oat cell carcinoma of gallbladder",
      "Oat cell carcinoma of the gallbladder",
      "gall bladder small cell carcinoma",
      "gallbladder Oat cell carcinoma",
      "gallbladder small cell NEC",
      "gallbladder small cell carcinoma",
      "gallbladder small cell neuroendocrine carcinoma",
      "small cell carcinoma of gall bladder",
      "small cell carcinoma of gallbladder",
      "small cell carcinoma of the gallbladder"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the gallbladder. It is characterized by the presence of malignant small cells."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2894,
      "label": "small cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050685",
          "EFO:0008524",
          "GARD:0022765",
          "ICDO:8041/3",
          "ICDO:8042/3",
          "MEDGEN:90748",
          "MESH:D018288",
          "NCIT:C3915",
          "NCIT:C4099",
          "SCTID:11010461000119101",
          "UMLS:C0334239"
        ],
        "synonyms": [
          "oat cell cancer",
          "oat cell carcinoma",
          "small cell NEC",
          "small cell cancer",
          "small cell car. (extrapulmonary)",
          "small cell carcinoma",
          "small cell carcinoma (extrapulmonary)",
          "small cell neuroendocrine carcinoma",
          "intermediate cell small cell carcinoma",
          "small cell carcinoma - intermediate cell",
          "small cell carcinoma, intermediate cell",
          "small cell carcinoma, intermediate cell (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neuroendocrine carcinoma composed of small malignant cells which are often said to resemble \"oat cells\" under the microscope. Small cell carcinoma most often affects the lungs. Clinically, this is often a rapidly growing cancer that spreads to distant sites early."
      },
      "child_count": 18,
      "reference_id": "MONDO:0000402"
    },
    {
      "id": 5174,
      "label": "gallbladder carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7085,
        7738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4948",
          "EFO:1001956",
          "GARD:0023412",
          "MEDGEN:116001",
          "NCIT:C3844",
          "SCTID:372140005",
          "UMLS:C0235782"
        ],
        "synonyms": [
          "gallbladder cancer",
          "Gall bladder carcinoma (adeno)",
          "Gall bladder carcinoma (adenocarcinoma)",
          "cancer of gallbladder",
          "cancer of the gallbladder",
          "carcinoma of gall bladder",
          "carcinoma of gallbladder",
          "carcinoma of the gallbladder",
          "gall bladder carcinoma",
          "gallbladder carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the gall bladder"
      },
      "child_count": 10,
      "reference_id": "MONDO:0003220"
    },
    {
      "id": 21455,
      "label": "gallbladder neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20460,
        21456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025405",
          "MEDGEN:474748",
          "NCIT:C96917",
          "UMLS:C3273115"
        ],
        "synonyms": [
          "gall bladder NET",
          "gall bladder neuroendocrine neoplasm",
          "gall bladder neuroendocrine tumor",
          "gall bladder neuroendocrine tumor, well differentiated, low or intermediate grade",
          "gall bladder neuroendocrine tumour",
          "gallbladder neuroendocrine neoplasm",
          "neuroendocrine neoplasm of gall bladder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the gallbladder. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024502"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2894,
      "label": "small cell carcinoma"
    },
    {
      "id": 5174,
      "label": "gallbladder carcinoma"
    },
    {
      "id": 21455,
      "label": "gallbladder neuroendocrine neoplasm"
    }
  ]
}