{
  "id": 7780,
  "label": "gastric neuroendocrine tumor G1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006227",
  "properties": {
    "xrefs": [
      "EFO:1000275",
      "GARD:0024341",
      "MEDGEN:83885",
      "NCIT:C4635",
      "UMLS:C0349529"
    ],
    "synonyms": [
      "gastric ECL cell NET",
      "gastric ECL cell NET G1",
      "gastric ECL cell, histamine-producing NET",
      "gastric ECL-cell carcinoid tumor",
      "gastric ECL-cell carcinoid tumour",
      "gastric NET G1",
      "gastric carcinoid tumor",
      "gastric carcinoid tumour",
      "gastric enterochromaffin-like cell carcinoid tumor",
      "gastric enterochromaffin-like cell carcinoid tumour",
      "gastric enterochromaffin-like cell neuroendocrine tumor",
      "gastric enterochromaffin-like cell neuroendocrine tumour",
      "grade 1 neuroendocrine neoplasm of stomach",
      "stomach NET G1",
      "stomach carcinoid tumor",
      "stomach carcinoid tumour",
      "stomach neuroendocrine neoplasm G1",
      "stomach neuroendocrine tumor, well differentiated, low grade"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A well differentiated, low grade neuroendocrine tumor (carcinoid tumor) that arises from the stomach. The vast majority of cases arise from the corpus-fundus region. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent. It may be associated with autoimmune chronic atrophic gastritis, multiple endocrine neoplasia type 1, or it may be sporadic."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7051,
      "label": "carcinoid tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19314
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0004243",
          "GARD:0024176",
          "HP:0100570",
          "ICD9:209.60",
          "ICDO:8240/3",
          "ICDO:8241/3",
          "MEDGEN:2838",
          "MESH:D002276",
          "NANDO:2200396",
          "NCIT:C2915",
          "SCTID:443492008",
          "UMLS:C0007095"
        ],
        "synonyms": [
          "NET G1",
          "carcinoid",
          "carcinoid tumor",
          "carcinoid tumor (disease)",
          "carcinoid tumour (disease)",
          "neuroendocrine neoplasm G1",
          "neuroendocrine tumor G1",
          "neuroendocrine tumour G1"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement."
      },
      "child_count": 7,
      "reference_id": "MONDO:0005369"
    },
    {
      "id": 16036,
      "label": "gastric neuroendocrine tumor, well differentiated, low or intermediate grade",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2885,
        5092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025056",
          "MEDGEN:474032",
          "NCIT:C95871",
          "ONCOTREE:SWDNET",
          "UMLS:C3272399"
        ],
        "synonyms": [
          "GNET",
          "gastric NET",
          "gastric NET G1/2",
          "gastric neuroendocrine tumor",
          "gastric neuroendocrine tumour",
          "gastric well differentiated endocrine tumor",
          "gastric well differentiated endocrine tumor/carcinoma",
          "gastric well differentiated endocrine tumour",
          "well-differentiated neuroendocrine tumors of the stomach",
          "well-differentiated neuroendocrine tumours of the stomach"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the stomach."
      },
      "child_count": 10,
      "reference_id": "MONDO:0015062"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7051,
      "label": "carcinoid tumor"
    },
    {
      "id": 16036,
      "label": "gastric neuroendocrine tumor, well differentiated, low or intermediate grade"
    }
  ]
}