{
  "id": 7798,
  "label": "hydatidiform mole",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006248",
  "properties": {
    "xrefs": [
      "EFO:1000298",
      "GARD:0010263",
      "ICD10WHO:O01",
      "ICD9:631",
      "ICDO:9100/0",
      "MEDGEN:9329",
      "MESH:D006828",
      "MedDRA:10020481",
      "NCIT:C3110",
      "OMIMPS:231090",
      "ONCOTREE:MP",
      "Orphanet:99927",
      "SCTID:44782008",
      "UMLS:C0020217",
      "icd11.foundation:946166369"
    ],
    "synonyms": [
      "hydatid mole",
      "hydatidiform mole",
      "molar pregnancy",
      "HYDM",
      "hydatidiform mole, recurrent"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A gestational trophoblastic disorder characterized by marked enlargement of the chorionic villi, hyperplasia of the villous trophoblastic cells and hydropic changes."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 4886,
      "label": "trophoblastic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4085",
          "MEDGEN:21708",
          "MESH:D014328",
          "NCIT:C3422",
          "UMLS:C0041182"
        ],
        "synonyms": [
          "neoplasm of trophoblast",
          "trophoblast neoplasm",
          "trophoblast neoplasm (disease)",
          "trophoblast tumor",
          "trophoblast tumour",
          "trophoblastic neoplasm",
          "trophoblastic neoplasm (morphologic abnormality)",
          "trophoblastic neoplasm NOS (morphologic abnormality)",
          "trophoblastic neoplasms",
          "trophoblastic tumor",
          "trophoblastic tumor (qualifier value)",
          "trophoblastic tumour",
          "trophoblastic tumour (qualifier value)",
          "tumor of trophoblast",
          "tumour of trophoblast"
        ],
        "definition": "A gestational or non-gestational neoplasm composed of neoplastic trophoblastic cells. Representative examples include hydatidiform mole and choriocarcinoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002872"
    },
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    },
    {
      "id": 20430,
      "label": "placenta neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7519,
        20520
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:105551",
          "NCIT:C4858",
          "UMLS:C0524541"
        ],
        "synonyms": [
          "neoplasm of placenta",
          "neoplasm of the placenta",
          "placenta neoplasm (disease)",
          "placenta neoplasms",
          "placenta tumor",
          "placenta tumors",
          "placenta tumour",
          "placenta tumours",
          "placental neoplasm",
          "placental tumor",
          "placental tumors",
          "placental tumour",
          "placental tumours",
          "tumor of placenta",
          "tumor of the placenta",
          "tumour of placenta",
          "tumour of the placenta",
          "trophoblastic tumor placental site",
          "trophoblastic tumour placental site"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the placenta."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021218"
    }
  ],
  "children": [
    {
      "id": 17226,
      "label": "complete hydatidiform mole",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017224",
          "MEDGEN:195706",
          "NCIT:C4871",
          "ONCOTREE:CHM",
          "Orphanet:254688",
          "SCTID:237249000",
          "UMLS:C0678213",
          "icd11.foundation:1338299833"
        ],
        "synonyms": [
          "classical hydatidiform Mole",
          "complete Mole",
          "complete hydatid Mole",
          "complete molar pregnancy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Complete hydatidiform mole is a type of hydatiform mole characterized by abnormal hyperplastic trophoblasts and hydropic villi due to fertilization of an enucleated ovocyte by one or two haploid spermatozoa that can manifest with vaginal bleeding accompanied by nausea and frequent vomiting, hyperemesis gravidarum, risk of spontaneous miscarriage, hyperthyroidism, and has the potential of developing into choriocarcinoma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0016785"
    },
    {
      "id": 17227,
      "label": "partial hydatidiform mole",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020749",
          "ICDO:9103/0",
          "MEDGEN:87258",
          "NCIT:C4293",
          "ONCOTREE:PHM",
          "Orphanet:254693",
          "SCTID:237250000",
          "UMLS:C0334529",
          "icd11.foundation:714020909"
        ],
        "synonyms": [
          "incomplete hydatid Mole",
          "incomplete hydatidiform mole",
          "incomplete molar pregnancy",
          "partial Mole",
          "partial hydatid Mole",
          "partial molar pregnancy",
          "PHM"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Partial hydatiform mole is a type of hydatiform mole characterized by abnormal hyperplastic trophoblasts and hydropic villi due to fertilization of a normal ovocyte by two spermatozoa or one abnormal spermatozoon (allowing for some fetal development), and that manifests with vaginal bleeding accompanied by nausea and frequent vomiting, hyperemesis gravidarum, hyperthyroidism and risk of spontaneous miscarriage."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016786"
    },
    {
      "id": 19992,
      "label": "invasive hydatidiform mole",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7798,
        18866
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019711",
          "ICDO:9100/1",
          "MEDGEN:3055",
          "MESH:D002820",
          "NCIT:C6985",
          "ONCOTREE:IHM",
          "Orphanet:99925",
          "SCTID:416669000",
          "UMLS:C0008493"
        ],
        "synonyms": [
          "chorioadenoma",
          "chorioadenoma Destruens",
          "chorioadenoma destruens",
          "invasive Mole",
          "invasive gestational trophoblastic neoplasm",
          "invasive hydatidiform Mole",
          "invasive hydatidiform mole",
          "IHM"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A complete hydatidiform mole or very rarely a partial mole that invades the myometrium."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020549"
    },
    {
      "id": 22405,
      "label": "hydatidiform mole, recurrent, 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018367",
          "MEDGEN:1677775",
          "OMIM:618431",
          "UMLS:C5193093"
        ],
        "synonyms": [
          "HYDATIDIFORM MOLE, RECURRENT, 3",
          "HYDM3"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0032746"
    },
    {
      "id": 22406,
      "label": "hydatidiform mole, recurrent, 4",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018368",
          "MEDGEN:1677210",
          "OMIM:618432",
          "UMLS:C5193094"
        ],
        "synonyms": [
          "HYDATIDIFORM MOLE, RECURRENT, 4",
          "HYDM4"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0032747"
    }
  ],
  "roots": [
    {
      "id": 4886,
      "label": "trophoblastic neoplasm"
    },
    {
      "id": 5714,
      "label": "hereditary disease"
    },
    {
      "id": 20430,
      "label": "placenta neoplasm"
    }
  ]
}