{
  "id": 7809,
  "label": "laryngeal small cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006265",
  "properties": {
    "xrefs": [
      "DOID:7144",
      "EFO:1000320",
      "GARD:0024352",
      "MEDGEN:233611",
      "NCIT:C6025",
      "UMLS:C1334378"
    ],
    "synonyms": [
      "laryngeal small cell carcinoma",
      "laryngeal throat small cell cancer",
      "larynx small cell carcinoma",
      "small cell carcinoma of larynx",
      "small cell carcinoma of the larynx"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0024623",
        "name": "otorhinolaryngologic disease"
      }
    ],
    "definition": "A rare carcinoma that arises from the larynx. It is characterized by the presence of small neuroendocrine cells. It metastasizes early and has an aggressive clinical course."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2894,
      "label": "small cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4255
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050685",
          "EFO:0008524",
          "GARD:0022765",
          "ICDO:8041/3",
          "ICDO:8042/3",
          "MEDGEN:90748",
          "MESH:D018288",
          "NCIT:C3915",
          "NCIT:C4099",
          "SCTID:11010461000119101",
          "UMLS:C0334239"
        ],
        "synonyms": [
          "oat cell cancer",
          "oat cell carcinoma",
          "small cell NEC",
          "small cell cancer",
          "small cell car. (extrapulmonary)",
          "small cell carcinoma",
          "small cell carcinoma (extrapulmonary)",
          "small cell neuroendocrine carcinoma",
          "intermediate cell small cell carcinoma",
          "small cell carcinoma - intermediate cell",
          "small cell carcinoma, intermediate cell",
          "small cell carcinoma, intermediate cell (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neuroendocrine carcinoma composed of small malignant cells which are often said to resemble \"oat cells\" under the microscope. Small cell carcinoma most often affects the lungs. Clinically, this is often a rapidly growing cancer that spreads to distant sites early."
      },
      "child_count": 18,
      "reference_id": "MONDO:0000402"
    },
    {
      "id": 4185,
      "label": "head and neck carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        7266
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1542",
          "MEDGEN:854345",
          "NCIT:C35850",
          "UMLS:C3887461"
        ],
        "synonyms": [
          "carcinoma of craniocervical region",
          "carcinoma of head and neck",
          "carcinoma of neck",
          "carcinoma of the head and neck",
          "craniocervical region carcinoma",
          "head and neck carcinoma",
          "neck carcinoma",
          "carcinoma of the neck",
          "head and neck cancer"
        ],
        "definition": "A carcinoma that arises from the head and neck region. Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma."
      },
      "child_count": 32,
      "reference_id": "MONDO:0002038"
    },
    {
      "id": 4457,
      "label": "laryngeal carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4451,
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2600",
          "GARD:0006862",
          "MEDGEN:108889",
          "NCIT:C4855",
          "SCTID:276975007",
          "UMLS:C0595989"
        ],
        "synonyms": [
          "cancer of larynx",
          "cancer of the larynx",
          "laryngeal cancer",
          "laryngeal throat cancer",
          "carcinoma of larynx",
          "carcinoma of the larynx",
          "laryngeal carcinoma",
          "larynx carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Carcinoma that arises from the laryngeal epithelium. More than 90% of laryngeal carcinomas are squamous cell carcinomas. The remainder are adenoid cystic carcinomas, mucoepidermoid carcinomas and carcinomas with neuroendocrine differentiation."
      },
      "child_count": 16,
      "reference_id": "MONDO:0002358"
    },
    {
      "id": 16044,
      "label": "laryngeal neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7231,
        19314,
        20312,
        21538
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5457",
          "GARD:0019758",
          "MEDGEN:232692",
          "NCIT:C6023",
          "Orphanet:100083",
          "SCTID:707625001",
          "UMLS:C1334374",
          "icd11.foundation:1502591214"
        ],
        "synonyms": [
          "laryngeal neuroendocrine neoplasm",
          "larynx NET",
          "larynx neuroendocrine neoplasm",
          "larynx neuroendocrine tumor",
          "larynx neuroendocrine tumor, well differentiated, low or intermediate grade",
          "larynx neuroendocrine tumour",
          "neuroendocrine neoplasm of larynx",
          "neuroendocrine neoplasm of the larynx",
          "laryngeal neuroendocrine tumor",
          "laryngeal neuroendocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A benign or malignant neoplasm with neuroendocrine differentiation that arises from the larynx. This category includes paraganglioma, carcinoid tumor, small cell carcinoma, and large cell neuroendocrine carcinoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0015070"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2894,
      "label": "small cell carcinoma"
    },
    {
      "id": 4185,
      "label": "head and neck carcinoma"
    },
    {
      "id": 4457,
      "label": "laryngeal carcinoma"
    },
    {
      "id": 16044,
      "label": "laryngeal neuroendocrine neoplasm"
    }
  ]
}