{
  "id": 7815,
  "label": "low grade fibromyxoid sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006272",
  "properties": {
    "xrefs": [
      "GARD:0024355",
      "ICD9:171.9",
      "MEDGEN:224814",
      "NCIT:C45202",
      "ONCOTREE:LGFMS",
      "SCTID:404088004",
      "UMLS:C1275282"
    ],
    "synonyms": [
      "low grade fibromyxoid sarcoma",
      "low-grade fibromyxoid sarcoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A low grade, late-metastasizing variant of fibrosarcoma characterized by alternating fibrous and myxoid areas and a whorling growth pattern. The neoplastic cells have a spindle morphology, and lack hyperchromasia or significant nuclear atypia. Approximately 40% of cases show the focal presence of collagen rosettes. A t(7;16)(q33;p11) translocation has been identified in the majority of cases, associated with the presence of FUS-CREB3L2 fusion protein. Rare cases carry the t(11;16)(p11;p11) translocation which is associated with the presence of the FUS-CREB3L1 fusion protein."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6886,
      "label": "fibrosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7762,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3355",
          "EFO:0002087",
          "GARD:0002327",
          "HP:0100244",
          "ICD9:171.9",
          "ICDO:8810/3",
          "MEDGEN:5178",
          "MESH:D005354",
          "MedDRA:10016632",
          "NANDO:2200060",
          "NCIT:C3043",
          "ONCOTREE:FIBS",
          "Orphanet:2030",
          "SCTID:443250000",
          "UMLS:C0016057"
        ],
        "synonyms": [
          "fibrocytic tumor",
          "fibrocytic tumour",
          "fibrosarcoma",
          "fibrosarcoma (disease)",
          "fibrosarcoma (excluding infantile fibrosarcoma)",
          "fibrosarcoma - not infantile",
          "fibrosarcoma, malignant",
          "malignant fibromatous neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A malignant mesenchymal fibroblastic neoplasm affecting the soft tissue and bone."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005164"
    }
  ],
  "children": [
    {
      "id": 7816,
      "label": "low grade fibromyxoid sarcoma with giant collagen rosettes",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7815
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000329",
          "GARD:0024356",
          "MEDGEN:310942",
          "NCIT:C45203",
          "UMLS:C1708749"
        ],
        "synonyms": [
          "hyalinizing spindle cell tumor with giant Rosettes",
          "hyalinizing spindle cell tumour with giant Rosettes"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A low grade fibromyxoid sarcoma characterized by the presence of prominent collagen rosettes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006273"
    }
  ],
  "roots": [
    {
      "id": 6886,
      "label": "fibrosarcoma"
    }
  ]
}