{
  "id": 7820,
  "label": "lung lymphangioleiomyomatosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006277",
  "properties": {
    "xrefs": [
      "DOID:3319",
      "EFO:1000334",
      "GARD:0003319",
      "ICD9:518.89",
      "MEDGEN:91161",
      "MedDRA:10049459",
      "NCIT:C38153",
      "ONCOTREE:LAM",
      "Orphanet:538",
      "SCTID:277844007",
      "UMLS:C0349649"
    ],
    "synonyms": [
      "Lymphangioleiomyomatosis",
      "lymphangioleiomyomatosis",
      "lung lymphangioleiomyomatosis",
      "lung lymphangiomyomatosis",
      "pulmonary lymphangiomyomatosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "Lymphangiomyomatosis involving the lungs and local lymph nodes. Patients usually present with chylous pleural effusion. The clinical course is variable. Patients with resectable lesions usually have a favorable clinical outcome. Patients with diffuse lesions usually have a progressive clinical course."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 12793,
      "label": "lymphangioleiomyomatosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7885
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024820",
          "ICD10CM:J84.81",
          "ICDO:9174/1",
          "MEDGEN:148366",
          "MESH:D018192",
          "NANDO:1200430",
          "NCIT:C3725",
          "OMIM:606690",
          "UMLS:C0751674",
          "icd11.foundation:902628446"
        ],
        "synonyms": [
          "lymphangioleiomyomatosis",
          "lymphangioleiomyomatosis, somatic",
          "lymphangiomyomatosis",
          "lung lymphangioleiomyomatosis",
          "pulmonary lymphangioleiomyomatosis",
          "LAM",
          "lymphangio-myomatosis"
        ],
        "definition": "A multifocal neoplasm with perivascular epithelioid cell differentiation affecting almost exclusively females of child-bearing age. It is characterized by the presence of smooth muscle and epithelioid cells and by the proliferation of lymphatic vessels. Sites of involvement include the lungs, mediastinum, and the retroperitoneum. It usually presents with chylous pleural effusion or ascites."
      },
      "child_count": 1,
      "reference_id": "MONDO:0011705"
    },
    {
      "id": 20025,
      "label": "lung PEComa",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7885,
        20356
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025181",
          "MEDGEN:1639012",
          "NCIT:C142783",
          "UMLS:C4684821"
        ],
        "synonyms": [
          "lung PEComa",
          "lung pecomatous tumor",
          "lung pecomatous tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A lung tumor that arises from perivascular epithelioid cells (PECs)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0020588"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 12793,
      "label": "lymphangioleiomyomatosis"
    },
    {
      "id": 20025,
      "label": "lung PEComa"
    }
  ]
}