{
  "id": 7824,
  "label": "lung signet ring cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006281",
  "properties": {
    "xrefs": [
      "DOID:0080305",
      "EFO:1000338",
      "GARD:0024359",
      "ICD9:162.9",
      "MEDGEN:310950",
      "NCIT:C45514",
      "SCTID:707407001",
      "UMLS:C1708782"
    ],
    "synonyms": [
      "lung signet ring cell carcinoma",
      "signet ring lung adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A morphologic variant of lung adenocarcinoma characterized by the presence of signet ring cells."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6791,
      "label": "lung adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        6944
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3910",
          "EFO:0000571",
          "MEDGEN:57744",
          "MESH:C538231",
          "NCIT:C3512",
          "ONCOTREE:LUAD",
          "Orphanet:415268",
          "SCTID:254626006",
          "UMLS:C0152013"
        ],
        "synonyms": [
          "adenocarcinoma of lung",
          "adenocarcinoma of the lung",
          "lung adenocarcinoma",
          "non-small cell lung adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the lung and is characterized by the presence of malignant glandular epithelial cells. There is a male predilection with a male to female ratio of 2:1. Usually lung adenocarcinoma is asymptomatic and is identified through screening studies or as an incidental radiologic finding. If clinical symptoms are present they include shortness of breath, cough, hemoptysis, chest pain, and fever. Tobacco smoke is a known risk factor."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005061"
    },
    {
      "id": 6819,
      "label": "signet ring cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3493",
          "EFO:0000698",
          "ICDO:8490/3",
          "MEDGEN:61663",
          "MESH:D018279",
          "NCIT:C3774",
          "UMLS:C0206696"
        ],
        "synonyms": [
          "signet ring carcinoma NOS (morphologic abnormality)",
          "signet ring cell adenocarcinoma",
          "signet ring cell carcinoma",
          "signet ring cell carcinoma (morphologic abnormality)"
        ],
        "definition": "A usually aggressive, poorly differentiated invasive adenocarcinoma characterized by the presence of malignant glandular cells in which the nucleus is pressed to one side by the presence of intracytoplasmic mucus. It may arise from the stomach, small and large intestine, ampulla of Vater, appendix, gallbladder, pancreas, lung, bladder, breast, and prostate gland."
      },
      "child_count": 11,
      "reference_id": "MONDO:0005092"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6791,
      "label": "lung adenocarcinoma"
    },
    {
      "id": 6819,
      "label": "signet ring cell carcinoma"
    }
  ]
}