{
  "id": 7830,
  "label": "malignancy in giant cell tumor of bone",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006287",
  "properties": {
    "xrefs": [
      "DOID:4719",
      "EFO:1000347",
      "GARD:0024361",
      "ICDO:9250/3",
      "MEDGEN:87263",
      "NANDO:2200052",
      "NCIT:C4304",
      "UMLS:C0334552"
    ],
    "synonyms": [
      "Dedifferentiated giant cell tumor",
      "Dedifferentiated giant cell tumour",
      "OSTEOCLASTOMA, malignant",
      "bone giant cell sarcoma",
      "giant cell bone sarcoma",
      "giant cell sarcoma of bone",
      "giant cell sarcoma of the bone",
      "giant cell tumor of bone, malignant",
      "giant cell tumor of bone, malignant (morphologic abnormality)",
      "giant cell tumour of bone, malignant",
      "giant cell tumour of bone, malignant (morphologic abnormality)",
      "malignancy in giant cell tumor of bone",
      "malignancy in giant cell tumor of the bone",
      "malignancy in giant cell tumour of the bone",
      "malignant giant cell tumor of bone",
      "malignant giant cell tumour of bone"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A malignant tumor that arises from the bone. It is characterized by the presence of an area of high grade sarcoma in an otherwise typical giant cell tumor (primary malignancy in giant cell tumor), or the presence of sarcoma in which the pre-existing giant cell tumor may or may not be apparent (secondary malignancy in giant cell tumor)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4492,
      "label": "malignant giant cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4297,
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2705",
          "ICDO:8003/3",
          "MEDGEN:90745",
          "NCIT:C4090",
          "UMLS:C0334229"
        ],
        "synonyms": [
          "giant cell tumor, malignant",
          "malignant giant cell neoplasm",
          "malignant giant cell tumor",
          "malignant tumor, giant cell type",
          "malignant tumor, giant cell type (morphologic abnormality)"
        ],
        "definition": "A malignant neoplasm characterized by then presence of atypical giant cells."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002402"
    },
    {
      "id": 20297,
      "label": "bone sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4262,
        6816
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080639",
          "GARD:0020547",
          "ICD9:170.9",
          "MEDGEN:352831",
          "MedDRA:10006007",
          "NCIT:C9312",
          "Orphanet:223727",
          "SCTID:448710000",
          "UMLS:C1704327"
        ],
        "synonyms": [
          "bone sarcoma",
          "osseous sarcoma",
          "sarcoma of bone",
          "sarcoma of the bone",
          "skeletal sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A sarcoma that arises from the bone. Representative examples are osteosarcoma and chondrosarcoma."
      },
      "child_count": 26,
      "reference_id": "MONDO:0021054"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4492,
      "label": "malignant giant cell tumor"
    },
    {
      "id": 20297,
      "label": "bone sarcoma"
    }
  ]
}