{
  "id": 7855,
  "label": "non-neoplastic bile duct disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006322",
  "properties": {
    "xrefs": [
      "EFO:1000400",
      "MEDGEN:476793",
      "NCIT:C35774",
      "UMLS:C3275160"
    ],
    "synonyms": [
      "non-neoplastic bile duct disorder"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A non-neoplastic disorder that affects the intrahepatic or extrahepatic bile ducts. Representative examples include cholangitis and biliary atresia."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 4900,
      "label": "bile duct disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6624
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4138",
          "MEDGEN:2240",
          "MESH:D001649",
          "NCIT:C96716",
          "SCTID:118926004",
          "UMLS:C0005395"
        ],
        "synonyms": [
          "bile duct disease",
          "bile duct disease or disorder",
          "bile duct disorder",
          "disease of bile duct",
          "disease or disorder of bile duct",
          "disorder of bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A disease involving the bile duct."
      },
      "child_count": 7,
      "reference_id": "MONDO:0002887"
    },
    {
      "id": 6875,
      "label": "endocrine system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:28",
          "EFO:0001379",
          "ICD9:259.8",
          "ICD9:259.9",
          "MEDGEN:4043",
          "MESH:D004700",
          "NANDO:1100009",
          "NANDO:2100109",
          "NCIT:C3009",
          "SCTID:362969004",
          "UMLS:C0014130"
        ],
        "synonyms": [
          "disease of endocrine system",
          "disease or disorder of endocrine system",
          "disorder of endocrine system",
          "endocrine disease",
          "endocrine disorder",
          "endocrine system disease",
          "endocrine system disease or disorder",
          "endocrine system disorder",
          "endocrinopathy",
          "thyroid or other glandular disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease involving the endocrine system."
      },
      "child_count": 48,
      "reference_id": "MONDO:0005151"
    }
  ],
  "children": [
    {
      "id": 6556,
      "label": "cholangitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7855,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9446",
          "ICD10CM:K83.0",
          "ICD9:576.1",
          "MEDGEN:40258",
          "MESH:D002761",
          "NCIT:C26718",
          "SCTID:82403002",
          "UMLS:C0008311",
          "icd11.foundation:1712178777"
        ],
        "synonyms": [
          "biliary tract infection",
          "biliary tree inflammation",
          "cholangitis",
          "inflammation of biliary tree"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An acute or chronic inflammatory process affecting the biliary tract."
      },
      "child_count": 18,
      "reference_id": "MONDO:0004789"
    },
    {
      "id": 8211,
      "label": "extrahepatic cholestasis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3937,
        7855
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13619",
          "EFO:1000933",
          "MEDGEN:2241",
          "MESH:D001651",
          "MedDRA:10008637",
          "SCTID:8262006",
          "UMLS:C0005398"
        ],
        "synonyms": [
          "cholestasis of extrahepatic bile duct",
          "extrahepatic bile duct cholestasis",
          "extrahepatic cholestasis (finding)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Impairment of the bile flow caused by an obstruction in the portion of the bile duct system located outside of the liver."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006757"
    },
    {
      "id": 8313,
      "label": "obstructive jaundice",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3937,
        7855
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13603",
          "EFO:1001068",
          "MEDGEN:43988",
          "MESH:D041781",
          "MedDRA:10029982",
          "SCTID:44018007",
          "UMLS:C0022354"
        ],
        "synonyms": [
          "obstructive hyperbilirubinemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A finding indicating increased bilirubin levels in the blood and urine, due to intrahepatic or extrahepatic obstruction of the biliary system."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006874"
    },
    {
      "id": 10132,
      "label": "biliary atresia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3937,
        7855
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13608",
          "GARD:0012010",
          "ICD10CM:Q44.2",
          "ICD9:751.61",
          "MEDGEN:14117",
          "MESH:D001656",
          "MedDRA:10003650",
          "NANDO:1200913",
          "NANDO:2200930",
          "NCIT:C34421",
          "NORD:1114",
          "Orphanet:30391",
          "SCTID:77480004",
          "UMLS:C0005411",
          "icd11.foundation:645741117"
        ],
        "synonyms": [
          "atresia of bile ducts",
          "biliary atresia, congenital",
          "congenital biliary atresia",
          "isolated atresia of bile ducts",
          "non-syndromic biliary atresia",
          "isolated biliary atresia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare, biliary tract disease characterized by progressive obliterative cholangiopathy of the intra- and extrahepatic bile ducts, occurring in the embryonic/ perinatal period, leading to severe and persistent neonatal jaundice and acholic stool."
      },
      "child_count": 6,
      "reference_id": "MONDO:0008867"
    },
    {
      "id": 12046,
      "label": "Caroli disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7855
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050876",
          "EFO:1001286",
          "GARD:0006002",
          "MEDGEN:57924",
          "MESH:D016767",
          "MedDRA:10013003",
          "NANDO:2200934",
          "NCIT:C84619",
          "NORD:896",
          "OMIM:600643",
          "Orphanet:53035",
          "SCTID:717232005",
          "UMLS:C0162510",
          "icd11.foundation:1757434239"
        ],
        "synonyms": [
          "CAROLI disease, isolated",
          "Caroli disease isolated",
          "congenital polycystic dilatation of intrahepatic bile ducts",
          "cystic dilatation of the intrahepatic biliary tree"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Caroli disease (CD) is a rare congenital liver disease characterized by non-obstructive cystic dilatations of the intra-hepatic and rarely extra-hepatic bile ducts."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010913"
    }
  ],
  "roots": [
    {
      "id": 4900,
      "label": "bile duct disorder"
    },
    {
      "id": 6875,
      "label": "endocrine system disorder"
    }
  ]
}